5 Mono 60 Mg Tablet Sr 10

5 Mono 60 MG Tablet Sr 10

Zydus Healthcare Ltd

Strip of 10 Units

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MRP ~~₹47.98~~

₹39.34

₹4.80/Units

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Composition

Isosorbide-5-mononitrate / Isosorbide Mononitrate (60 Mg)

5 Mono 60 MG Tablet Sr 10 is primarily used to prevent angina pectoris, a type of chest pain related to heart disease. This medicine belongs to the class of organic compounds known as isosorbide and is well known for its ability to relax and widen blood vessels.

While the main use of this medicine is to prevent angina in people with coronary artery disease, it also improves the supply of blood and oxygen to the heart while reducing its workload. This makes it easier for the heart to pump blood throughout your body.

Before starting this medicine, you must consult your doctor regarding the appropriate dosage and frequency for your condition. You should also inform your doctor about any pre-existing medical conditions or current medications you might be taking. If you notice any side effects while using this medicine, immediately notify your doctor. For the best results, it's important to continue taking the medicine for the duration recommended by your doctor.

5 Mono 60 MG Tablet Sr 10 is used for the following:

Prevention and treatment of angina pectoris
Follow-up care after a heart attack to prevent further heart damage
Management of pulmonary hypertension, a type of high blood pressure that affects the arteries in the lungs and the right side of your heart

Directions for Use of 5 Mono 60 MG Tablet Sr 10

While taking 5 Mono 60 MG Tablet Sr 10, adhere to the following instructions:

Swallow the tablet whole with a glass of water.
The medicine should not be crushed or chewed.
It's crucial that you take the medicine at the same time every day.
Avoid making any changes to your dosing schedule without consulting your doctor.

5 Mono 60 MG Tablet Sr 10 is taken orally.

Side Effects of 5 Mono 60 MG Tablet Sr 10

When you take 5 Mono 60 MG Tablet Sr 10, you may experience the following side effects:

Headache
Dizziness
Nausea
Increased sweating
Flushing: This refers to a warm feeling and redness on the face and neck.
Blurred vision: You might have difficulty focusing your eyes on objects.
Increased or Decreased heartbeat
Coughing and nasal congestion
Tinnitus: Perception of noise or ringing in the ears when there is no external sound present.
Edema
Fatigue
Flu-like symptoms
Malaise

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of 5 Mono 60 MG Tablet Sr 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing common side effects:

Dizziness: Sit or lie down as soon as you feel dizzy to prevent falls.
Nausea: Taking the medicine with meals can help reduce feelings of sickness.

5 Mono 60 MG Tablet Sr 10 contains Isosorbide Mononitrate (60 Mg) sustained-release, which has a specific mechanism of action on the body:

Conversion to Nitric Oxide (NO): The active ingredient in this medicine gets converted into nitric oxide within your body
Activation of Guanylate Cyclase: Nitric oxide activates an enzyme called guanylate cyclase in the smooth muscle cells lining your blood vessels
Increase in cGMP Synthesis: The activated enzyme increases the synthesis of cyclic guanosine monophosphate (cGMP)
Vasodilation: The increased levels of cGMP cause dephosphorylation of the myosin light chain in smooth muscles. This process results in relaxation and increased blood flow in arteries, veins, and cardiac tissue (vasodilation), thus reducing strain on the heart muscle
Improved Blood Flow: This dilation makes it easier for blood to flow through the coronary arteries, providing more oxygen to the heart muscle and reducing its workload and angina

Pregnancy

Caution is advised while taking 5 Mono 60 MG Tablet Sr 10 if you are pregnant. It is recommended to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised when administering this medication to breastfeeding women. It is recommended to consult your doctor before taking this medicine.

Alcohol

Avoid consuming alcohol while on this medication, as it can potentiate the side effects of 5 Mono 60 MG Tablet Sr 10, especially dizziness and lightheadedness.

Liver

If you have any liver problems or conditions, it's advisable to discuss them with your doctor before starting on 5 Mono 60 MG Tablet Sr 10 as this medicine may affect liver function.

Kidney

If you have a history of kidney problems, caution is advised before using 5 Mono 60 MG Tablet Sr 10. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Dizziness, a common side effect of 5 Mono 60 MG Tablet Sr 10, can affect your ability to drive or operate machinery. Use caution while performing activities that require alertness.

Allergy

If you have known hypersensitivity to nitrates or any other components of 5 Mono 60 MG Tablet Sr 10, avoid taking this medicine. Always inform your doctor about your allergies.

Children

This medication is not intended for use in children under the age of 18 years. Always consult a doctor before giving any medicine to a child.

Older Patients

Older patients should take 5 Mono 60 MG Tablet Sr 10 under medical supervision due to their increased susceptibility to its side effects. It is recommended that you consult your doctor before taking this medicine.

Interactions of 5 Mono 60 MG Tablet Sr 10

Drug-Drug Interactions

5 Mono 60 MG Tablet Sr 10 interacts with the following medicines:

Antihypertensives: When combined with amlodipine, 5 Mono 60 MG Tablet Sr 10 may increase the risk of low blood pressure.
Diuretics: Furosemide taken with 5 Mono 60 MG Tablet Sr 10 can intensify blood pressure-lowering effects.
Erectile Dysfunction Medicines: Concomitant use of medicines like sildenafil or tadalafil with 5 Mono 60 MG Tablet Sr 10 can amplify the blood pressure-lowering effects.

Drug-Food Interactions

Drug-Disease Interactions

5 Mono 60 MG Tablet Sr 10 interacts with the following diseases:

Low blood pressure or shock: Angicor 20 Tablet has a vasodilatory effect which can further decrease blood pressure in patients suffering from low blood pressure or shock.
Thyroid disorders, anemia, or increased intracranial pressure: This medication should be used cautiously in patients with these conditions as it may exacerbate symptoms.
Kidney or liver disorders: Caution is advised when using Angicor 20 Tablet in patients with impaired kidney or liver function due to the potential impact on metabolism and excretion of the medication.

Daily Dose

You should take the daily dose of 5 Mono 60 MG Tablet Sr 10 as advised by your doctor. The dosage could vary depending on individual factors, like the severity of your condition and your response to the medicine. It's crucial to follow the prescribed dosage without exceeding it unless your doctor tells you otherwise.

Over Dose

If you accidentally take more than the prescribed dose of 5 Mono 60 MG Tablet Sr 10, you may experience symptoms such as severe headache, dizziness, or an unusually fast heartbeat. However, if symptoms persist or worsen, consult your doctor.

Missed Dose

If you forget to take a dose of 5 Mono 60 MG Tablet Sr 10, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store your 5 Mono 60 MG Tablet Sr 10 at room temperature away from light and moisture.
Always keep this medicine out of the reach of children.

Maintain a low-sodium diet and engage in regular, moderate-intensity physical activity after consulting your doctor.

Fact Box

Drug Category	Nitrate Compound
Therapeutic Category	Anti-Anginal
Available Dosage Types	Tablet SR
Habit Forming	No
Ailment	Angina, Coronary Artery Disease

What is 5 Mono 60 MG Tablet Sr 10 used for?

It is used for managing heart-related chest pain or angina in adults with coronary artery disease.

How does 5 Mono 60 MG Tablet Sr 10 work?

It relaxes the blood vessels, making it easier for the heart to pump blood, thus reducing its workload.

Can 5 Mono 60 MG Tablet Sr 10 be used to treat an acute angina attack?

No, this medicine is not for treating acute angina attacks; it's only meant to prevent them.

How should I take 5 Mono 60 MG Tablet Sr 10?

Swallow it whole with water on an empty stomach. As advised by your doctor, take it at the same time each day.

What are some side effects of 5 Mono 60 MG Tablet Sr 10?

Common side effects include headache, dizziness, nausea, and flushing. If symptoms persist or worsen, consult your doctor immediately.

Can I drink alcohol while taking 5 Mono 60 MG Tablet Sr 10?

No, consuming alcohol while taking this medicine can increase the risk of adverse effects like dizziness and lightheadedness.

Are there any medications that interact with 5 Mono 60 MG Tablet Sr 10?

Yes, certain medications, such as PDE-5 inhibitors and other nitrates, can interact with this medicine. Always inform your doctor about all the medicines you're taking.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Zydus Tower, Satellite Cross Roads, Sarkhej - Gandhinagar Highway, Ahmedabad Ahmedabad GJ 380015 IN

Country of origin: INDIA

References

monoket®. (2003). monoket® tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020215s024lbl.pdf
DailyMed - ISOSORBIDE MONONITRATE tablet, extended release. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cd439861-2e23-4e0e-bcdc-48e2ebdc4943
Isosorbide - StatPearls - NCBI bookshelf. (2023, May 16). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK557839/
Isosorbide mononitrate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01020

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