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Vonoprazan

Uses of Vonoprazan

  • Vonoprazan is primarily used to treat acid-related disorders of the upper gastrointestinal tract and is a potassium-competitive acid blocker (P-CAB). 
  • It is effective in managing conditions such as erosive esophagitis (EE), gastroesophageal reflux disease (GERD), duodenal and gastric ulcers, and Zollinger-Ellison syndrome.
  • Additionally, Vonoprazan is used in combination with antibiotics to eradicate Helicobacter pylori and treat drug-induced peptic ulcers and reflux esophagitis.

Side effects of Vonoprazan

  • Diarrhoea

  • Nausea

  • Abdominal pain

  • Headache

  • Nasopharyngitis

How Vonoprazan works

  • Vonoprazan is categorised as a potassium-competitive acid blocker.

  • It works by inhibiting the proton pumps in the stomach lining, reducing the production of stomach acid. Unlike traditional proton pump inhibitors (PPIs), it blocks acid secretion more rapidly and consistently, making it useful in treating conditions like gastroesophageal reflux disease (GERD) and peptic ulcers.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Vonoprazan is available for use as oral tablets.

  • This medicine is administered orally.

Age and Dose Restrictions

  • This medicine is meant for use in adults. Specific guidance for children's use has not been provided, suggesting it is primarily intended for adult patients.

Contraindications

  • Vonoprazan is contraindicated in patients with a known hypersensitivity to the medicine or any of its ingredients.

Other Medications to Avoid

  • This medicine may interact with antibiotics (such as clarithromycin), chemotherapy agents (like methotrexate), cardiac glycosides (including digoxin), anticoagulants (such as warfarin), and antiretrovirals (like atazanavir).

Overdose and Missed Dose

  • An overdose of Vonoprazan may lead to an increased incidence of its side effects such as diarrhoea and headache. If you suspect an overdose, it is important to seek medical attention promptly.

  • If you miss a dose of Vonoprazan, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing mild diarrhoea, consider taking the medication with food or increasing fluid intake.

  • For headaches, adjusting the timing of the medication might help mitigate this side effect.

Use in Driving and Operating Machinery

  • Vonoprazan does not specifically impair your ability to drive or operate machinery. However, if you experience side effects like headaches or dizziness, it may be wise to avoid such activities until these effects subside.

Use in Pregnancy and Lactation

  • Vonoprazan should only be used during pregnancy or lactation if the potential benefits justify the potential risks. It is important to consult a doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with severe liver problems should exercise caution when taking Vonoprazan due to the metabolism of the medicine being potentially affected by liver functionality.

  • It is also advisable for individuals with serious kidney issues to consult a doctor before using Vonoprazan as dosage adjustments may be necessary.

Special Dietary and Lifestyle Recommendations

  • To manage conditions like gastroesophageal reflux disease (GERD) which Vonoprazan is used for, consider eating smaller, more frequent meals instead of three large ones.

  • Avoid foods that trigger reflux such as spicy foods, chocolate, caffeine, and acidic fruits.

  • If you are dealing with GERD or erosive esophagitis, elevating the head of your bed by a few inches can help reduce symptoms at night.

  • Reducing alcohol intake can also decrease stomach acid production which complements the action of Vonoprazan.

  • Smoking cessation is advised as smoking can increase stomach acidity and delay healing of the stomach lining.

Frequently asked questions

No, Vonoprazan is not a steroid. It is a potassium-competitive acid blocker (P-CAB) medication, which is a class of medicines used to manage acid-related disorders of the upper gastrointestinal tract.

No evidence suggests Vonoprazan directly affects sleep patterns. However, every individual may react differently to medication. If you observe any changes in your sleep after starting this medication, you should consult your doctor.

There is no evidence that suggests that Vonoprazan has any significant effect on fertility. If you are planning to conceive and are concerned about the effects of this medication on fertility, it would be best to discuss this with your doctor.

No specific dietary restrictions are requied for patients taking Vonoprazan. It is always a good idea to maintain a balanced diet while on any medication unless directed otherwise by your doctor.

Vonoprazan is usually taken as per the doctor's prescription and the severity of the condition being managed. It is crucial to follow the prescribed dosage and frequency to ensure its effectiveness and safety.

The onset of action for Vonoprazan can vary depending on the individual and the condition being managed. Usually, some improvement in symptoms may be noticed within a few days, but for full benefit, it may take up to several weeks.

Yes, you do need a prescription from your doctor to buy Vonoprazan. It is not an over-the-counter medication.

Terms & Conditions

Available medicines for VONOPRAZAN
Vono 20 Tablet 10
Vono 20 Tablet 10
Dr. Reddys Laboratories Ltd
Pack of 10 Units
₹123.00
MRP ₹150.00
18.00% OFF
Lupivon 20 Tablet 10
Lupivon 20 Tablet 10
Lupin Ltd
Pack of 10 Units
₹138.58
MRP ₹169.00
18.00% OFF
Vozan 20 Tablet 10
Vozan 20 Tablet 10
Eris Lifesciences Ltd
Pack of 10 Units
₹139.40
MRP ₹170.00
18.00% OFF
Kabvie 20 Tablet 10
Kabvie 20 Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹138.58
MRP ₹169.00
18.00% OFF
Vonefi 20 Tablet 10
Vonefi 20 Tablet 10
Abbott India Ltd.
Pack of 10 Units
₹129.56
MRP ₹158.00
18.00% OFF
Vonomac 20 Tablet 10
Vonomac 20 Tablet 10
Macleods Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹142.27
MRP ₹173.50
18.00% OFF
Vono 10 Tablet 10
Vono 10 Tablet 10
Dr. Reddys Laboratories Ltd
Pack of 10 Units
₹73.80
MRP ₹90.00
18.00% OFF
Vonogress 20 Tablet 10
Vonogress 20 Tablet 10
La Renon
Pack of 10 Units
₹155.80
MRP ₹190.00
18.00% OFF

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