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Varenicline

Uses of Varenicline

  • The primary use of Varenicline is to assist individuals in quitting smoking. It belongs to the class of nicotine receptor partial agonists.

  • There are no secondary uses for this medicine as it strictly focuses on assisting people in reducing their dependence on nicotine.

Side effects of Varenicline

  • Nausea

  • Insomnia and abnormal dreams

  • Constipation

  • Vomiting

  • Drowsiness

How Varenicline works

  • Varenicline is a nicotinic receptor partial agonist.

  • It works by partially stimulating nicotine receptors in the brain, which reduces withdrawal symptoms and cravings, while also blocking nicotine from attaching to these receptors. This helps to reduce the pleasure derived from smoking and makes quitting easier.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Varenicline is available in the form of tablets taken via the oral route.

Age and Dose Restrictions

  • This medicine is intended for use in adults. Specifically, it is not approved for use in children due to the lack of established safety and efficacy.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to any component of Varenicline.

  • Patients with severe renal impairment need to avoid this medication.

  • It should also be avoided by individuals with a history of seizures.

Other Medications to Avoid

  • This medicine may interact with nicotine replacement therapies (such as nicotine patches and gums), which are also used for smoking cessation but are not recommended for combined use.

  • It may affect how blood thinners like warfarin (such as Coumadin) work, particularly as smoking cessation can alter blood levels.

Overdose and Missed Dose

  • An overdose of Varenicline may intensify its side effects such as nausea, sleep disturbances, and unusual dreams. If suspected, it is crucial to seek immediate medical attention.

  • If you miss a dose of Varenicline, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea, try taking the medicine with food or a large glass of water.

  • For dry mouth, sipping water regularly or using sugar-free candies can help stimulate saliva production.

Use in Driving and Operating Machinery

  • Varenicline may impair your ability to drive or operate machinery. Caution should be exercised, and activities requiring alertness should be avoided if you experience drowsiness or dizziness after taking this medication.

Use in Pregnancy and Lactation

  • The safety of Varenicline during pregnancy and lactation has not been established. Therefore, its use is not recommended unless specifically advised by a doctor after assessing the potential benefits against risks.

Caution in Other Conditions

  • Caution is advised when using Varenicline in patients with moderate to severe renal impairment as dosage adjustment may be necessary.

  • Patients with a history of psychiatric illness should also be closely monitored due to the risk of exacerbation of their condition.

Special Dietary and Lifestyle Recommendations

  • To support smoking cessation efforts while taking Varenicline, engage in regular physical activity as exercise can help reduce stress and manage withdrawal symptoms.

  • Adopt a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to improve overall health and cope with changes after quitting smoking.

  • Avoid caffeine and alcohol as they can trigger smoking cravings and affect sleep patterns.

  • Consider joining support groups or counselling services that provide encouragement and practical advice on living smoke-free.

Frequently asked questions

No, Varenicline is not a steroid. It is a medication used to help people quit smoking by reducing their cravings and the pleasurable effects of tobacco.

Yes, one of the common side effects of Varenicline can be insomnia and abnormal dreams. If you experience these side effects, it is important to consult your doctor.

There is no specific effect of Varenicline on fertility. However, as with any medication, if you are planning to conceive, you should discuss this with your doctor before starting any new medication.

There are no specific diet restrictions when taking Varenicline. However, it is recommended that the medication should be taken after eating with a full glass of water.

Yes, it is safe to take Varenicline daily as per the prescription and direction of your doctor.

Varenicline reaches steady state levels in 4-5 days but the quit date is usually set for 1-2 weeks after starting therapy. Noticeable effects build over several weeks.

It is typically recommended to take Varenicline after eating with a full glass of water.

Terms & Conditions

Available medicines for VARENICLINE
Varenismart 0.5mg Tablet 10
Varenismart 0.5mg Tablet 10
Healing Pharma
Pack of 10 Units
₹300.70
MRP ₹599.00
49.80% OFF
Champix 1 MG Tablet 25
Champix 1 MG Tablet 25
Pfizer Ltd
Pack of 25 Units
₹1394.00
MRP ₹1700.00
18.00% OFF
Varenismart 1mg Tablet 10
Varenismart 1mg Tablet 10
Healing Pharma
Pack of 10 Units
₹519.90
MRP ₹999.00
47.96% OFF

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