Topiramate

Expert Advice

Dosage Forms Available

• Topiramate can be taken orally (tablets, sprinkle capsules, extended-release capsules, oral solution).

Age and Dose Restrictions

• Topiramate can be used alone for patients over 6 years old and as an add-on therapy for those over 2 years old, and is suitable for preventing migraines in adults and adolescents aged 12 and older.

Contraindications

• Topiramate should not be taken by patients who have hypersensitivity to any component of this medicine. It is also contraindicated for patients who have metabolic acidosis and are concurrently taking metformin.

Other Medications to Avoid

• Topiramate may interact with CNS depressants (e.g., diazepam, hydrochlorothiazide, pioglitazone, and amitriptyline).

Overdose and Missed Dose

• Overdose symptoms may include agitation, altered consciousness, blurred vision, dizziness, drowsiness, speech problems, double vision, abnormal coordination, and confusion. Seek immediate emergency medical attention if an overdose occurs.

• If you miss a dose of Topiramate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled one. Do not double the dose to make up for a forgotten one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Keep yourself well-hydrated to manage the side effects of dry mouth.

• If you experience drowsiness or dizziness, try to take the medicine at bedtime.

Use in Driving and Operating Machinery

• Topiramate may impair your ability to drive or operate heavy machinery due to its potential side effects such as drowsiness, slow thinking, and difficulty concentrating. Avoid such activities if you experience these effects.

Use in Pregnancy and Lactation

• Topiramate may cause harm to the foetus, therefore, it is not recommended for use in pregnancy unless necessary. Consult your doctor before using this medication during pregnancy and breastfeeding.

Caution in Other Conditions

• Extra caution should be taken when using Topiramate in patients with kidney disease or undergoing hemodialysis, as they may need slower titration and more frequent monitoring. In elderly patients, slower titration might be needed due to greater sensitivity and a higher risk of adverse reactions.

Special Dietary and Lifestyle Recommendations

• Avoid triggers that may lead to seizures or migraines. These can be certain foods, drinks, stress, hormonal changes, or lack of sleep.

• Have regular medical check-ups to monitor kidney function and overall health.

Frequently asked questions

Terms & Conditions