Tibolone

Expert Advice

Dosage Forms Available

• Tibolone is available for use as oral tablets.

Age and Dose Restrictions

• This medicine is meant for adult women, specifically postmenopausal women.

Contraindications

• This medicine is contraindicated in women with unexplained vaginal bleeding, active history of venous thromboembolism, active or recent thromboembolic disease (e.g., angina, myocardial infarction), liver disease or liver function test abnormalities, known or suspected oestrogen-dependent malignant tumours, and porphyria.

Other Medications to Avoid

• Tibolone can interact with anticonvulsants (such as phenytoin and carbamazepine), antimicrobials (like rifampicin and griseofulvin), antiretrovirals (including ritonavir and nelfinavir), and herbal supplements containing St. John's wort.

Overdose and Missed Dose

• An overdose of Tibolone may lead to symptoms such as nausea, dizziness, and vaginal bleeding. If these symptoms occur, it is important to seek medical advice immediately.

• If you miss a dose of Tibolone, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten tablet.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

• If experiencing nausea, try taking the medicine with food or a glass of milk.

• For headaches or dizziness, it may help to take the medicine at bedtime.

Use in Driving and Operating Machinery

• Tibolone may cause dizziness or blurred vision. It is advised to avoid driving or operating heavy machinery until you know how Tibolone affects you.

Use in Pregnancy and Lactation

• Tibolone is contraindicated during pregnancy and while breastfeeding. It can harm the developing baby.

• If you are planning to become pregnant or are breastfeeding, consult your doctor before starting Tibolone.

Caution in Other Conditions

• Women with liver disease should exercise caution when using Tibolone due to its extensive metabolism in the liver.

• Caution should also be exercised in women with a history of thromboembolic disorders due to an increased risk of blood clots.

Special Dietary and Lifestyle Recommendations

• A diet rich in calcium and vitamin D is recommended to help manage bone health in menopause. Foods such as dairy products, green leafy vegetables, and fish can be beneficial.

• Regular weight-bearing exercise like walking or jogging can help maintain bone density.

• Smoking cessation is strongly advised as smoking can accelerate bone loss.

• Limiting alcohol intake can also reduce the risk of osteoporosis.

• Ensure adequate hydration by drinking plenty of water throughout the day.

Frequently asked questions

Terms & Conditions