Sodium Carboxymethyl Cellulose
Uses of Sodium Carboxymethyl Cellulose
Sodium Carboxymethyl Cellulose is primarily used as a viscosity-enhancing agent and lubricant in eye drops for treating dry eyes, helping to soothe irritation and prevent further discomfort by keeping the eyes moist.
It is used as a stabilizer, emulsifier, and thickening agent in various pharmaceutical formulations, especially in topical and oral products. It belongs to the group of medicines known as cellulose derivatives.
Side effects of Sodium Carboxymethyl Cellulose
Eye irritation and redness with ophthalmic use
Stinging and tearing with ophthalmic use
Temporary minor burning, stinging or irritation
How Sodium Carboxymethyl Cellulose works
Sodium Carboxymethyl Cellulose is a lubricant, pharmaceutical excipient, and thickener.
It acts by increasing the viscosity of formulations, such as eye drops, to improve comfort and effectiveness. The higher consistency helps to lubricate and protect the surface of the eye, rendering the formulation more efficacious.
Also, as a solubility enhancer in oral medications, it boosts the bioavailability of certain medicines. This means it helps the body to absorb more of the medicine, making it more effective.
In topical products like creams and ointments, it acts as an emulsifier and stabiliser. It keeps the different ingredients in these formulations evenly distributed, ensuring their uniform application and effect on your skin.
Certified content
Written By
BDS, MDS
Reviewed By
Bachelor of Dental Surgery
Expert Advice
Dosage Forms Available
Sodium Carboxymethyl Cellulose is available for use via the ophthalmic route in the form of eye drops and topically as an ointment.
It is also available for topical use in creams and lotions.
Age and Dose Restrictions
This medicine is meant for use by adults and children. Specific age restrictions may depend on the formulation and concentration of Sodium Carboxymethyl Cellulose used in the product.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to Sodium Carboxymethyl Cellulose or other cellulose derivatives.
Other Medications to Avoid
This combination may interact with other eye medications (such as antihistamine eye drops including ketotifen and olopatadine), and oral medications that alter tear production (such as anticholinergics like atropine).
Overdose and Missed Dose
An overdose of Sodium Carboxymethyl Cellulose, especially in eye drop form, is generally not harmful. In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
Overdose of Sodium Carboxymethyl Cellulose in topical form is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.
If a dose is missed, apply the medicine when you remember but skip it if it is almost time for your next scheduled application. Do not double the amount to be applied.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If eye irritation occurs due to eye drops, blinking several times can help spread the eye drop evenly across the eye surface.
For topical forms, if irritation occurs, reducing the frequency of application may help alleviate discomfort.
Use in Driving and Operating Machinery
The ophthalmic form of Sodium Carboxymethyl Cellulose may cause temporary blurred vision after application. Avoid driving or operating heavy machinery until your vision is clear.
Use in Pregnancy and Lactation
It is advisable to consult a doctor before using Sodium Carboxymethyl Cellulose during pregnancy or while breastfeeding. The safety profile has not been fully established under these conditions.
Caution in Other Conditions
Patients with severe allergic conditions should exercise caution when using products containing Sodium Carboxymethyl Cellulose due to potential hypersensitivity reactions.
Special Dietary and Lifestyle Recommendations
For individuals using Sodium Carboxymethyl Cellulose for dry eyes, increasing hydration by drinking plenty of water can be beneficial.
Incorporating omega-3 fatty acids into your diet, found in fish like salmon and nuts like walnuts, can help improve overall eye health.
For skin conditions managed by topical forms of Sodium Carboxymethyl Cellulose, maintaining a clean and moisturised skin regimen can enhance the effectiveness of the treatment.
Frequently asked questions
What is Sodium Carboxymethyl Cellulose used for?
Sodium Carboxymethyl Cellulose is widely used in the pharmaceutical, food, and cosmetic industries. In pharmaceuticals, it is used as an excipient in oral solid dosage forms to enhance medicine bioavailability, as a thickening agent in ophthalmic preparations like eye drops to increase comfort and effectiveness, and as an emulsifier and stabilizer in topical preparations like creams and ointments.
Can Sodium Carboxymethyl Cellulose cause allergic reactions?
In rare cases, Sodium Carboxymethyl Cellulose might cause allergic reactions such as hives, itching, and rashes. If you experience any sudden or severe symptoms, please consult your doctor immediately.
Is Sodium Carboxymethyl Cellulose safe for use in food?
Yes, Sodium Carboxymethyl Cellulose is generally recognized as safe (GRAS) for use in food manufacturing as a thickener, emulsifier, and stabilizer.
Can Sodium Carboxymethyl Cellulose be used in cosmetics?
Yes, Sodium Carboxymethyl Cellulose is used as a thickening agent and stabilizer in personal care products including cosmetics.
Does Sodium Carboxymethyl Cellulose have any impact on eyesight?
When used in ophthalmic preparations like eye drops, Sodium Carboxymethyl Cellulose may temporarily cause blurred vision. Therefore, it is advisable to avoid driving or operating machinery until your vision clears.
How does Sodium Carboxymethyl Cellulose work in eye drops?
Sodium Carboxymethyl Cellulose works in eye drops by acting as a lubricant, which helps relieve dryness and irritation in the eyes. It binds to the surface of the eye forming a protective layer that mimics natural tears. This layer increases the moisture retention on the ocular surface, reducing evaporation and maintaining hydration.
Can I take other medicines while using Sodium Carboxymethyl Cellulose?
Sodium Carboxymethyl Cellulose may affect the absorption or efficacy of concurrently administered medications. It is recommended to keep a list of all products used and consult a doctor before combining medications.
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