Sisomycin

Expert Advice

Dosage Forms Available

• Sisomycin is available in various dosage forms, including ointments and creams for topical application to treat localized skin infections, as well as eye and ear drops for ophthalmic and otic use, respectively.

• The primary routes of administration are topical for skin infections and ophthalmic or otic for eye or ear infections.

Age and Dose Restrictions

• Sisomycin is intended for use in adult patients.

• Paediatric safety and efficacy have not been established.

Contraindications

• Sisomycin is contraindicated in patients with known hypersensitivity to sisomicin or other aminoglycosides.

• It is contraindicated in patients with severe renal impairment without close monitoring and dose adjustment.

Other Medications to Avoid

• Sisomycin may interact with other antibiotics (such as gentamicin, tobramycin), diuretics (such as furosemide, bumetanide), and muscle relaxants (such as pancuronium, vecuronium). It may also interact with nephrotoxic agents (such as amphotericin B, cisplatin) and medications used for anaesthesia (such as halothane, isoflurane).

Overdose and Missed Dose

• In case of an overdose of Sisomycin, particularly with topical application, excessive use may lead to skin irritation or an increased risk of systemic absorption, especially if applied over large areas or on broken skin. If you suspect an overdose or experience unusual symptoms, it’s important to contact your doctor for advice.

• For a missed dose of Sisomycin, apply it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply extra to make up for the missed dose, as this could increase the risk of irritation or other side effects.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• If you experience mild skin irritation, reduce the frequency of application or apply a thinner layer of the ointment or cream. If irritation persists, discontinue use and consult your doctor.

• Symptoms like itching, swelling, or rash may indicate an allergic reaction. Stop using Sisomycin immediately and seek medical advice. Your doctor may recommend an alternative treatment.

Use in Driving and Operating Machinery

• Sisomycin has no direct effects on the ability to drive or operate machinery. However, caution is advised if experiencing side effects such as dizziness or hearing changes.

Use in Pregnancy and Lactation

• Sisomycin is not recommended during pregnancy (Category D) or while breastfeeding. It may cause harm to the fetus and can be excreted in breast milk.

• Always consult your doctor if you are pregnant or breastfeeding before starting treatment with Sisomycin.

Caution in Other Conditions

• Caution should be exercised when administering Sisomycin to patients with renal impairment or auditory dysfunction.

• Adequate hydration must be maintained, and renal function monitored closely during the treatment.

Special Dietary and Lifestyle Recommendations

• Keep the affected area clean and dry to promote healing and prevent further infection. Regularly wash your hands before and after applying the medication.

• Avoid exposing the treated area to harsh chemicals, soaps, or cosmetics that could irritate the skin or interfere with the healing process.

• While there are no specific dietary restrictions, maintaining a balanced diet can support your overall immune system, which may aid in faster recovery from infections.

• If you are applying Sisomycin on areas exposed to sunlight, consider using protective clothing or sunscreen to avoid further irritation, as some skin treatments can make the skin more sensitive to sunlight.

Frequently asked questions

Terms & Conditions