Pomalidomide
Uses of Pomalidomide
Pomalidomide is primarily used for the management of multiple myeloma, a type of blood cancer affecting plasma cells. It belongs to the class of medications known as immunomodulatory agents.
Side effects of Pomalidomide
Fatigue
Anaemia
Constipation
Nausea
How Pomalidomide works
Pomalidomide is an immunomodulatory agent.
It works by enhancing the body's immune system to attack and kill the abnormal plasma cells in the bone marrow causing multiple myeloma. Additionally, Pomalidomide possesses anti-angiogenic properties, meaning it can block the formation of new blood vessels which tumours need to grow and spread.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Pomalidomide can be taken orally (capsule).
Age and Dose Restrictions
This medicine is meant for adults who have previously undergone at least two prior therapies for the management of multiple myeloma.
Contraindications
Pomalidomide is contraindicated in patients with a history of severe hypersensitivity reactions to the medicine or any of its constituents.
Other Medications to Avoid
Pomalidomide may interact with immunosuppressants (cyclosporine), anticoagulants (warfarin), antifungals (ketoconazole), antibiotics (rifampin) and anticonvulsants (carbamazepine and phenytoin).
Overdose and Missed Dose
An overdose of Pomalidomide can lead to severe health complications, including blood disorders and nerve damage. If you suspect an overdose, seek medical attention immediately.
In case of a missed dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not double the dosage to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage constipation.
Taking Pomalidomide with meals can help manage nausea.
Use in Driving and Operating Machinery
Pomalidomide may cause dizziness and fatigue. Therefore, avoid driving or operating heavy machinery if you experience these symptoms after taking this medicine.
Use in Pregnancy and Lactation
This medicine is contraindicated in pregnant women due to the risk of severe birth defects. Breastfeeding women should consult their doctor before taking this medicine.
Caution in Other Conditions
Pomalidomide should be used with caution in patients with renal impairment, as it is primarily excreted by the kidneys.
Special Dietary and Lifestyle Recommendations
Regular check-ups are recommended to monitor your health during Pomalidomide therapy.
Avoid exposure to infections by maintaining good hygiene practices.
Frequently asked questions
Is Pomalidomide a steroid?
No, Pomalidomide is not a steroid. It belongs to the class of medications known as immunomodulatory medicines.
Does Pomalidomide have any effect on sleep?
Pomalidomide is not typically associated with affecting sleep. Nevertheless, each person may react differently to medications. If you experience severe sleep disturbances, consult your doctor.
Will Pomalidomide affect fertility?
Pomalidomide is not typically associated with affecting fertility in humans, it is recommended for men and women of reproductive potential to use effective contraception during and after treatment due to the risk of harm to the baby.
Is it safe to take Pomalidomide daily?
Yes, it is safe to take Pomalidomide daily if prescribed by your doctor. Always follow your doctor's instructions on how and when to take this medication.
How much time does Pomalidomide take to work?
The time it takes for Pomalidomide to work can vary among individuals. In some clinical trials, patients experienced a response within the first few cycles of treatment.
What is the best time to take Pomalidomide?
Pomalidomide can be taken at any time of the day, with or without food. However, it is usually recommended that the medication is taken at approximately the same time each day for best results.
What is the duration of treatment with Pomalidomide?
The duration of treatment with Pomalidomide will depend on your doctor's instructions and individual response to the medicine.
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