Pentoxifylline

Expert Advice

Dosage Forms Available

• Pentoxifylline is available for oral use in the form of extended-release tablets.
• In addition, It is available in immediate-release tablets, oral liquid, and injectable forms.

Age and Dose Restrictions

• This medicine is intended for use in adults only.

Contraindications

• Pentoxifylline is contraindicated in patients with recent cerebral and/or retinal haemorrhage.
• It should not be used by those who have previously shown intolerance to Pentoxifylline or other methylxanthines such as caffeine, theophylline, and theobromine.

Other Medications to Avoid

• Pentoxifylline may interact with NSAIDs (such as ibuprofen and naproxen), anticoagulants (such as warfarin and heparin), and antiplatelet agents (such as aspirin and clopidogrel).
• Before starting any prescription or over-the-counter medications, it is crucial to consult a doctor, as using these medicines alongside Pentoxifylline may not be recommended.

Overdose and Missed Dose

• An overdose of Pentoxifylline may cause symptoms such as flushing, fever, hypotension, drowsiness, agitation, seizures, arrhythmias, and vomiting. If you observe any of these symptoms, inform your doctor immediately.
• If you forget to take a dose of Pentoxifylline, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not double up on doses.

Management of Side Effects

Most side effects of Pentoxifylline are temporary and generally harmless, resolving upon discontinuation of this medicine. However, if you experience severe side effects or worsening of symptoms, consult your doctor.

• Drinking plenty of fluids can help manage gastrointestinal disturbances like nausea and vomiting.
• Resting in a quiet, dark room may help with dizziness and headache.

Use in Driving and Operating Machinery

• Pentoxifylline may cause dizziness or headaches. Avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

• Pentoxifylline is categorized as pregnancy category C. It should only be used in pregnancy or lactation if clearly needed. Always consult your doctor before using this medicine during these periods.

Caution in Other Conditions

• Patients with renal or hepatic impairment should exercise caution when taking Pentoxifylline as the levels of the medication and its metabolites may be increased in these conditions.

Special Dietary and Lifestyle Recommendations

• Regularly engaging in physical activities, like walking, can improve blood circulation, which is beneficial for those with peripheral artery disease and intermittent claudication.
• Eating a balanced diet rich in fruits, vegetables, lean proteins, whole grains, and healthy fats can contribute to overall cardiovascular health.
• Avoid smoking or use of other tobacco products as they can worsen symptoms of peripheral artery disease.

Frequently asked questions

Terms & Conditions