Pefloxacin
Uses of Pefloxacin
Pefloxacin is used to manage various bacterial infections and belongs to the group of fluoroquinolone antibiotics.
Side effects of Pefloxacin
Nausea and vomiting
Diarrhoea
Headache and dizziness
Skin rash and itching
How Pefloxacin works
Pefloxacin is a broad-spectrum fluoroquinolone antibiotic.
It works by inhibiting two important enzymes in bacteria, DNA gyrase and topoisomerase IV. These enzymes are essential for the bacteria to replicate their DNA, repair it, and recombine it. When Pefloxacin blocks these enzymes, the bacteria cannot multiply or spread. This leads to the death of the bacterial cells, thus managing the bacterial infection.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Pefloxacin is available via oral route (tablets). It can also be administered intravenously (injection).
Age and Dose Restrictions
Pefloxacin is meant for adults above 18 years of age.
Contraindications
This medicine is contraindicated in patients with known allergies to Pefloxacin or other quinolones. It is also contraindicated in patients taking tizanidine.
Other Medications to Avoid
Pefloxacin may interact with antacids (such as aluminium hydroxide, sucralfate, ferrous sulfate, and zinc sulfate), anticoagulants (such as warfarin), and NSAIDs (like ibuprofen and naproxen).
Overdose and Missed Dose
An overdose of Pefloxacin may cause severe abdominal discomfort, nausea, and seizures. If you suspect an overdose, seek immediate medical attention.
If you forget to take your dose of Pefloxacin, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one. Never double the dose to catch up.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If you experience nausea or vomiting, taking your medicine with food might help.
If you become dizzy or lightheaded, sit or lie down until the symptoms pass.
Use in Driving and Operating Machinery
Pefloxacin may make you feel dizzy or lightheaded. Avoid driving or operating heavy machinery if you experience these symptoms.
Use in Pregnancy and Lactation
Pefloxacin is not recommended during pregnancy and breastfeeding unless your doctor advises it. Always consult your doctor before using this medicine if you are pregnant or breastfeeding.
Caution in Other Conditions
Patients with kidney disease should use Pefloxacin cautiously, as dosage adjustments may be required.
Individuals with a history of seizures should also exercise caution while taking this medicine due to the risk of seizure exacerbation.
Special Dietary and Lifestyle Recommendations
To avoid photosensitivity reactions, limit exposure to sunlight and UV light, such as tanning beds. Wear protective clothing and use sunscreen with a high SPF when outdoors.
Regular hand washing and avoiding close contact with people with infections can help prevent catching or spreading infections.
Frequently asked questions
Can Pefloxacin affect my mood?
While it is not common, some people taking Pefloxacin have reported experiencing mood changes or disturbances such as agitation, anxiety, depression, and even hallucinations. If you notice any changes in your mood or if you start to feel anxious or depressed while taking this medicine, consult your doctor immediately.
Are there natural alternatives to taking Pefloxacin?
There are no natural alternatives that can replace the antibacterial action of Pefloxacin in managing bacterial infections. If you prefer a more holistic approach to healthcare, discuss this with your doctor who can guide you accordingly while ensuring you receive effective treatment for your infection.
Is there a specific time of day I should take Pefloxacin?
Pefloxacin can be taken at any time of the day but should ideally be taken at the same time each day to maintain a constant level in the body. Always follow your doctor's instructions regarding the timing and frequency of doses.
Is Pefloxacin a steroid?
No, Pefloxacin is not a steroid. Pefloxacin is a broad-spectrum fluoroquinolone antibiotic.
Can Pefloxacin cause sun sensitivity?
Yes, Pefloxacin can make your skin more sensitive to sunlight leading to sunburn more easily. You should avoid excessive exposure to sunlight or UV light and use sunscreen while taking this medicine.
Is it safe to use Pefloxacin daily?
Yes, Pefloxacin is generally safe for daily use as per your doctor's prescription. It is important to follow the prescribed dosage and duration meticulously.
Does Pefloxacin affect sleep patterns?
Generally, Pefloxacin does not directly affect sleep patterns. However, side effects such as insomnia or dizziness may impact your sleep. If you experience these symptoms persistently, it is recommended to consult your doctor for advice.
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