Paracetamol/acetaminophen + Promethazine
Uses of Paracetamol/acetaminophen + Promethazine
Mainly, Paracetamol/Acetaminophen + Promethazine is used to relieve symptoms of the common cold, flu, and allergies in adults and children 12 years and older. This medicine combination belongs to the group of pain relievers and antihistamines.
The medicine also helps in managing various symptoms associated with these conditions, such as headache, fever, sore throat, runny nose, sneezing, minor aches and pains, itchy watery eyes and itching of the nose or throat.
How Paracetamol/acetaminophen + Promethazine works
The combination of Paracetamol/Acetaminophen + Promethazine falls under the therapeutic category of analgesic and antihistamine/antiemetic combination.
Paracetamol/Acetaminophen is an analgesic and antipyretic that functions by inhibiting the production of certain chemicals in the brain, namely prostaglandins, which are responsible for transmitting pain signals and inducing fever. Thus, it effectively reduces pain and fever.
Promethazine, the antihistamine component, operates by blocking histamine, a substance produced by the body during an allergic reaction. This action helps to relieve allergy symptoms like a runny nose, sneezing, and itchy or watery eyes. When combined, these two active ingredients work hand in hand to effectively alleviate multiple symptoms related to colds, flu, and allergies.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Paracetamol/Acetaminophen + Promethazine can be taken orally (tablets and syrup).
Age and Dose Restrictions
This medication is meant for adults and children above 12 years of age.
Contraindications
Paracetamol/Acetaminophen + Promethazine is contraindicated in patients with known allergies to either paracetamol or promethazine.
It is also contraindicated in patients with severe liver disease, respiratory depressions (conditions like COPD and asthma), narrow-angle glaucoma, CNS depression due to alcohol, sedatives, or other depressants, and benign prostatic hyperplasia (BPH).
Other Medications to Avoid
Paracetamol/Acetaminophen + Promethazine may interact with antidepressants (such as fluoxetine and sertraline), sedatives or sleeping pills (like diazepam and lorazepam), narcotic pain relievers (such as morphine and codeine), muscle relaxants (like baclofen and tizanidine), seizure medications (such as gabapentin and levetiracetam), and antihistamines (such as loratadine and cetirizine).
Overdose and Missed Dose
An overdose of Paracetamol/Acetaminophen + Promethazine can lead to drowsiness, seizures, widened pupils, or trouble breathing. In case of overdose, seek immediate medical attention.
If you forget to take a dose of this medicine, take it as soon as you remember. But avoid repeating the dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking lots of water can help manage dry mouth caused by this medication.
Standing up slowly from a sitting or lying position can help reduce dizziness caused by this medicine.
Use in Driving and Operating Machinery
Paracetamol/Acetaminophen + Promethazine may cause drowsiness or dizziness. Therefore, caution is advised while driving or operating heavy machinery.
Use in Pregnancy and Lactation
Consult your doctor before using Paracetamol/Acetaminophen + Promethazine during pregnancy or breastfeeding.
Caution in Other Conditions
Patients with liver disease, kidney disease, or a seizure disorder should exercise caution when taking Paracetamol/Acetaminophen + Promethazine.
Special Dietary and Lifestyle Recommendations
Ensure adequate hydration to help reduce the severity of cold symptoms.
Regularly clean your hands to prevent catching colds and flu.
Frequently asked questions
Is Paracetamol/Acetaminophen + Promethazine a steroid?
No, Paracetamol/Acetaminophen + Promethazine is not a steroid. Paracetamol/Acetaminophen is a pain reliever and fever reducer, while Promethazine is an antihistamine that relieves allergy symptoms.
Does Paracetamol/Acetaminophen + Promethazine have any effect on sleep?
Yes, one of the common side effects of this combination is drowsiness. Therefore, it may make you feel sleepy after taking it.
Will Paracetamol/Acetaminophen + Promethazine affect fertility?
There is currently no known effect of Paracetamol/Acetaminophen + Promethazine on fertility. However, if you have concerns about fertility, it is best to consult your doctor for advice.
Is it safe to take Paracetamol/Acetaminophen + Promethazine daily?
Paracetamol/Acetaminophen + Promethazine should be taken as directed by your doctor. It is typically used to manage symptoms of the common cold, flu and allergies.
How much time does Paracetamol/Acetaminophen + Promethazine take to work?
This medicine usually starts working within 20-60 minutes of taking a dose, with peak effects occurring within 2-3 hours. Individual results will vary depending on your specific condition.
What is the best time to take Paracetamol/Acetaminophen + Promethazine?
The best time to take this medication is according to your doctor's instructions. It can be taken with or without food. However, taking it with food may help reduce stomach upset.
Is Paracetamol/Acetaminophen + Promethazine available over the counter, or do I need a prescription?
This medicine usually requires a prescription and is not typically available over the counter. It's always best to consult your doctor before starting any new medication.
Paracetamol/acetaminophen + Promethazine in other salts
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