Oxybutynin
Uses of Oxybutynin
The primary use of Oxybutynin is for the management of overactive bladder syndrome, and it falls under the category of anticholinergic and antispasmodic medications.
In some cases, Oxybutynin may be used off-label to manage symptoms of bedwetting in children aged 6 years and above when other treatments have not been successful.
Side effects of Oxybutynin
Dry mouth
Constipation
Drowsiness and dizziness
Blurred vision
Nausea and vomiting
How Oxybutynin works
Oxybutynin is used to treat overactive bladder.
It is an anticholinergic and antispasmodic medicine.
It works by blocking the action of a neurotransmitter called acetylcholine on certain receptors in the detrusor muscle of the bladder, known as muscarinic receptors. This hinders the transmission of signals that cause involuntary contractions in the bladder muscle, thus relaxing it. As a result, it helps delay the initial urge to urinate, increases bladder capacity, and reduces urinary frequency and urgency, which are common symptoms of overactive bladder syndrome.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Oxybutynin can be taken orally (immediate-release tablet, extended-release tablet or syrup) and applied topically (transdermal patch).
Age and Dose Restrictions
This medicine is primarily meant for adults and children above 6 years of age.
Contraindications
Oxybutynin is contraindicated in individuals with known hypersensitivity to Oxybutynin or any inactive ingredients. The medication should not be used in patients with urinary or gastric retention, uncontrolled narrow-angle glaucoma, or severe ulcerative colitis.
Other Medications to Avoid
Oxybutynin may interact with other anticholinergic medications (such as atropine and scopolamine), CYP3A4 inhibitors (such as ketoconazole and erythromycin), and central nervous system (CNS) depressants (like clonazepam, alprazolam).
Overdose and Missed Dose
An overdose of Oxybutynin may cause symptoms such as restlessness, tachycardia (fast heart rate), flushing, fever, hallucinations, and fainting. If you observe these symptoms, inform your doctor immediately.
If you forget to take a dose of Oxybutynin, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose. Do not take a double dose to compensate for the missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For dry mouth, try chewing sugar-free gum or sucking on sugar-free hard candy. You can also frequently sip water or use a saliva substitute.
For constipation, eat dietary fiber, drink enough water, and exercise regularly.
If you experience dizziness or light-headedness, rise slowly when getting up from a sitting or lying position.
For dry eyes, you can use eye lubricants.
Use in Driving and Operating Machinery
Oxybutynin may cause drowsiness, dizziness, or blurred vision which may affect your ability to drive or operate machinery. It is advised to avoid driving or using heavy machinery until you know how the medicine affects you.
Use in Pregnancy and Lactation
Always consult your doctor before using this medicine during pregnancy and caution is advised when breastfeeding. Consult your doctor for more advice.
Caution in Other Conditions
Patients with pre-existing conditions such as narrow-angle glaucoma, gastrointestinal disorders like gastroesophageal reflux disease (GERD) or delayed gastric emptying, urinary retention or bladder outlet obstruction, myasthenia gravis, and cognitive impairment should exercise caution when taking this medicine.
Special Dietary and Lifestyle Recommendations
Drink plenty of fluids (unless your doctor advises otherwise) to avoid becoming dehydrated.
Avoid drinks that can irritate your bladder such as coffee, tea and citrus juices.
Frequently asked questions
Can Oxybutynin cause weight gain?
No. Oxybutynin, which is an anticholinergic and antispasmodic medication, does not directly cause weight gain. However, if you notice any significant changes in your weight while using this medicine, it may be best to consult your doctor.
Will Oxybutynin impact my menstrual cycle?
Oxybutynin is not directly associated with affecting the menstrual cycle. However, all bodies are different and can react differently to medicines. If you have any concerns or notice any changes in your menstrual cycle while using this medicine, please consult your doctor.
What is the best time to take Oxybutynin?
The best time to take Oxybutynin depends on your individual treatment plan and the specific formulation of the medication prescribed by your doctor.
Is there a natural alternative to Oxybutynin?
While there are certain lifestyle changes and exercises that may help manage overactive bladder symptoms, there are no known natural alternatives that have the same effect as Oxybutynin. Always consult your doctor before starting any new treatment or stopping prescribed medication.
Is Oxybutynin suitable for vegans and vegetarians?
The suitability of Oxybutynin for vegans and vegetarians depends on the specific formulation and manufacturer of the medicine. Some may contain non-vegan or non-vegetarian ingredients. It is best to consult your pharmacist or physician for more information.
How much time does Oxybutynin take to work?
The time it takes for Oxybutynin to work can vary among individuals, but most people begin noticing improvement in their symptoms within a few weeks of starting the medication.
Is it safe to take Oxybutynin daily?
Yes, it is safe to take Oxybutynin daily when prescribed by your doctor. This medication is often used long-term to manage symptoms of overactive bladder.
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