Ofloxacin + Tinidazole
Uses of Ofloxacin + Tinidazole
- Ofloxacin + Tinidazole is a combination antibiotic belonging to the fluoroquinolone and nitroimidazole groups, primarily used to treat specific bacterial and parasitic infections.
- It is effective against bacterial infections in the urinary tract, kidneys, prostate, genital organs, lungs, airways, skin, bones, joints, and soft tissues. Additionally, it helps manage pelvic inflammatory disease, intra-abdominal infections, infectious diarrhea caused by susceptible bacteria, and parasitic infections such as trichomoniasis, giardiasis, and amebiasis.
Side effects of Ofloxacin + Tinidazole
Nausea
Vomiting
Diarrhoea
Abdominal pain
Dizziness
How Ofloxacin + Tinidazole works
Ofloxacin, the first component, belongs to the class of antibiotics called fluoroquinolones. It works by blocking the action of two important bacterial enzymes, DNA gyrase and topoisomerase IV. These enzymes are vital for bacteria to replicate and repair their DNA. By inhibiting these enzymes, Ofloxacin stops the multiplication of bacteria.
Tinidazole, the other active ingredient in this combination, is a nitroimidazole antibiotic. It works by directly damaging the DNA of harmful bacteria and certain protozoa, which leads to their death. It specifically targets anaerobic bacteria and protozoa.
Certified content
Written By
MD Ayurveda
Reviewed By
Bachelor of Dental Surgery
Expert Advice
Dosage Forms Available
Ofloxacin + Tinidazole can be taken orally (tablet).
Age and Dose Restrictions
This combination medicine is meant for adults and children above 12 years of age.
Contraindications
Ofloxacin + Tinidazole is contraindicated in patients with known allergy to ofloxacin, tinidazole, or any other quinolone or nitroimidazole antibiotics. It is also contraindicated in patients taking tizanidine.
Other Medications to Avoid
Ofloxacin + Tinidazole may interact with antacids, iron, calcium and other metal cation containing products (such as multivitamin tablets), blood thinners (such as warfarin), antidiabetic agents (like metformin and insulin), nonsteroidal anti-inflammatory medicines (like ibuprofen and naproxen), respiratory medications (like theophylline), and immunosuppressants (like cyclosporine).
Overdose and Missed Dose
Overdose of Ofloxacin + Tinidazole may lead to severe adverse reactions such as confusion, drowsiness, dizziness, nausea, vomiting, tremors and seizures. In such cases, immediate medical attention is required.
If you miss a dose of Ofloxacin + Tinidazole, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and take your next dose at the scheduled time.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage nausea or vomiting, try taking this medicine with or after a meal.
To manage headache or dizziness, avoid sudden changes in posture and stay hydrated.
In case of genital itching or discharge, maintain good personal hygiene.
Use in Driving and Operating Machinery
Ofloxacin + Tinidazole may cause side effects like dizziness, confusion or hallucinations that can affect your ability to drive or operate machinery. Avoid such activities if you experience these side effects.
Use in Pregnancy and Lactation
Ofloxacin + Tinidazole is not recommended for use during pregnancy or while breastfeeding unless recommended by your doctor. Always consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding.
Caution in Other Conditions
Patients with a history of tendinitis, tendon rupture, myasthenia gravis, peripheral neuropathy or central nervous system disorders should exercise caution when taking Ofloxacin + Tinidazole.
Caution is also advised in patients with a history of serious allergic reactions or liver damage.
Special Dietary and Lifestyle Recommendations
Regular hand washing and practising good personal hygiene can help prevent the spread of bacterial infections.
Avoiding close contact with people who are sick can also help prevent infections.
If you have been prescribed Ofloxacin + Tinidazole for a digestive tract infection, it may be beneficial to include probiotics in your diet to restore the balance of healthy bacteria in your gut.
Frequently asked questions
Can Ofloxacin + Tinidazole influence my mood or emotions?
Some central nervous system side effects like anxiety and confusion have been reported. If you notice any unusual emotional effects, it is wise to consult your doctor.
Are there any natural alternatives to Ofloxacin + Tinidazole for managing infections?
While some natural remedies may offer certain health benefits, they should not be used as a substitute for prescribed antibiotics like Ofloxacin + Tinidazole. Antibiotics are necessary to effectively manage bacterial and parasitic infections. Always consult your doctor before trying any alternative remedies.
How long does Ofloxacin + Tinidazole stay in the body after I stop taking the medicine?
The half-lives of ofloxacin and tinidazole are approximately 5-8 hours and 12-14 hours, respectively. Thus, both these substances should be mostly eliminated from your body within 2-3 days after the last dose. However, individual factors like age, health status, and metabolism can affect this time frame.
Does Ofloxacin + Tinidazole have any effect on menstruation?
No! However, if you experience any irregular menstruation or other unusual symptoms while taking this medicine, consult your doctor.
Will Ofloxacin + Tinidazole affect my appetite?
Though appetite changes are not listed as common side effects of Ofloxacin + Tinidazole, individual reactions can vary. If you notice a significant change in your appetite while taking this medicine, consult your doctor.
Is there a vegetarian or vegan version of Ofloxacin + Tinidazole available?
The active ingredients in Ofloxacin + Tinidazole itself are not derived from animal sources. However, the capsule or tablet form might contain components derived from animals. If you are vegetarian or vegan, check with your pharmacist about the constituents of the specific brand of medicine.
Can I develop an addiction or dependency on Ofloxacin + Tinidazole?
No, Ofloxacin + Tinidazole is an antibiotic combination and does not have addictive properties. However, it is essential to take this medication only as prescribed by the doctor to avoid misuse or unnecessary exposure to possible side effects.
Ofloxacin + Tinidazole in other salts
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