Ofloxacin + Ornidazole + Racecadotril
Uses of Ofloxacin + Ornidazole + Racecadotril
Ofloxacin + Ornidazole + Racecadotril is primarily used for managing acute diarrhoea and gastrointestinal infections. This combination belongs to the group of antibiotics and anti-secretory medications.
It is also used to manage conditions such as travellers' diarrhoea, infectious diarrhoea, acute diarrhoeal episodes in irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD), and acute diarrhoea of unspecified aetiology.
Side effects of Ofloxacin + Ornidazole + Racecadotril
Nausea
Vomiting
Abdominal pain
Headache
Dizziness
How Ofloxacin + Ornidazole + Racecadotril works
Ofloxacin, an antibiotic, works by stopping the action of certain enzymes called DNA gyrase and topoisomerase IV that bacteria need to divide and multiply. By doing so, it prevents the bacteria from growing, thereby helping to eliminate the infection.
Ornidazole, another type of antibiotic, interacts with the DNA inside bacteria and protozoa (single-celled organisms), causing damage to their proteins and genetic material. This damage stops these microorganisms from surviving and multiplying, clearing the infection.
Racecadotril lowers the secretion of fluids into the intestine. It achieves this by blocking an enzyme called enkephalinase which is involved in water and electrolyte secretion in the body. This helps reduce diarrhoea symptoms without affecting normal gut movement. Together, these three components work in synergy to manage acute diarrhoea and gastrointestinal infections effectively.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Ofloxacin + Ornidazole + Racecadotril is available for use via the oral route (tablet).
Age and Dose Restrictions
This combination is intended for use in adults, particularly in those experiencing acute episodes of diarrhoea and gastrointestinal infections.
Contraindications
Ofloxacin + Ornidazole + Racecadotril is not recommended for patients with known allergies to any of the three components. This medication should also be avoided by individuals with a history of tendon disorders, epilepsy or seizure disorders, conditions causing prolonged QT intervals or arrhythmias, and glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Other Medications to Avoid
Ofloxacin + Ornidazole + Racecadotril may interact with antiarrhythmics (such as amiodarone and sotalol), antipsychotics (haloperidol and pimozide), anticonvulsants (phenytoin), anticoagulants (warfarin), and antivirals (ritonavir).
Overdose and Missed Dose
In case of an overdose of this medication, symptoms may include severe dizziness, nausea, or vomiting. If you suspect an overdose, contact your doctor immediately.
If you miss a dose of this medication, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular medication schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage symptoms of dehydration that may result from diarrhoea.
Resting and avoiding strenuous physical activity can minimise feelings of weakness or tiredness that may occur.
Use in Driving and Operating Machinery
This combination may cause dizziness or sleepiness. Therefore, it is not advisable to drive or operate heavy machinery until you know how this medicine affects you.
Use in Pregnancy and Lactation
It is advised to consult your doctor before using Ofloxacin + Ornidazole + Racecadotril during pregnancy or while breastfeeding.
Caution in Other Conditions
Patients with liver impairment should use Ofloxacin + Ornidazole + Racecadotril with caution, as it could potentially worsen their condition.
Special Dietary and Lifestyle Recommendations
Adopting a diet low in fats and high in fibre may help manage gastrointestinal conditions.
It is crucial to maintain adequate hydration, especially during episodes of diarrhoea.
Reducing stress levels through relaxation techniques such as yoga or meditation may help improve gastrointestinal health.
Regular hand hygiene practices may help prevent the spread of infectious agents causing diarrhoea.
Frequently asked questions
Does Ofloxacin + Ornidazole + Racecadotril combination have any effect on sleep?
Ofloxacin + Ornidazole + Racecadotril is not directly associated with affecting sleep. However, some side effects, like dizziness, may indirectly influence sleep patterns.
Will Ofloxacin + Ornidazole + Racecadotril affect fertility?
Ofloxacin + Ornidazole + Racecadotril is not directly associated with affecting fertility. Consult your doctor for specific details.
Is it safe to take Ofloxacin + Ornidazole + Racecadotril daily?
The medicine should be taken as per the doctor's recommendation.
How much time does Ofloxacin + Ornidazole + Racecadotril take to work?
This combination medicine starts working soon after oral administration; however, the time taken to see symptomatic relief can vary based on the severity of the condition.
What is the best time to take Ofloxacin + Ornidazole + Racecadotril?
This medicine should be taken as directed by the doctor. Generally, it is recommended to be taken with food to reduce possible gastric side effects.
Can I take Ofloxacin + Ornidazole + Racecadotril without a prescription?
No, Ofloxacin + Ornidazole + Racecadotril is a prescription medication and should only be taken under the supervision of a doctor.
Can I take Ofloxacin + Ornidazole + Racecadotril with other medicines?
Ofloxacin, a component of the combination, interacts with many medications like antiarrhythmics, and antipsychotics. It is important to inform your doctor about all the medicines you are currently taking to avoid potential medicine interactions.
Ofloxacin + Ornidazole + Racecadotril in other salts
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