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Nicoumalone

ANTICOAGULANT

Uses of Nicoumalone

  • Nicoumalone (Acenocoumarol) is used to treat and prevent blood clots, helping reduce the risk of stroke or heart attack.

Side effects of Nicoumalone

  • Haemorrhage

How Nicoumalone works

  • Nicoumalone (Acenocoumarol) falls under the novel oral anticoagulant (NOAC) category. It inhibits vitamin K reductase, resulting in the depletion of vitamin K in its reduced form (vitamin KH2). It prevents the production of potentially hazardous blood clots. Although it doesn't dissolve existing blood clots, it prevents them from enlarging and triggering severe complications.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

  • You should notify your doctor if you are pregnant, planning for pregnancy, or already breastfeeding. Taking Nicoumalone / Acenocoumarol at the same time every day will have the most beneficial effect. Doctors recommend a Nicoumalone / Acenocoumarol to reduce your risk of heart attack and stroke. Nicoumalone / Acenocoumarol may increase your risk of bleeding. Always use precaution while shaving, operating with sharp tools, or cutting your fingernails or toenails, or engaging in contact sports (e.g. football, wrestling). Before any surgery, inform your doctor that you are taking Nicoumalone / Acenocoumarol. While using the medication Nicoumalone/Acenocoumarol, avoid making any sudden, significant dietary changes. You should consult your doctor immediately if you notice blood in your stool (black, tarry stools or bright red blood), urine, or vomit. Do not combine alcohol with Nicoumalone / Acenocoumarol because it could enhance adverse effects.

Frequently asked questions

No, using it during pregnancy may not be safe. Although there is a lack of information in human research, there is evidence from animal studies that this is harmful to a fetus. Your doctor will consider the risks and benefits before a prescription is given. Please consult your physician.

Within 2 to 3 hours, you must experience the benefit of Nicoumalone / Acenocoumarol.

Yes, it's likely safe to take Nicoumalone / Acenocoumarol during breastfeeding. According to limited human studies, the medicine may not provide a significant risk to the unborn child.

Yes, it should be used with precaution, specifically if you have a history of liver disorders or problems. Some patients may need a dosage modification of Nicoumalone / Acenocoumarol. If you have any problems, you should consult your doctor.

Yes, it should be used with precaution, specifically if you have a history of kidney disorders or problems. Some patients may need a dosage modification of Nicoumalone / Acenocoumarol. If you have any problems, you should consult your doctor.

It is not recommended to use any anticoagulants (like heparin, dipyridamole, clopidogrel, ticlopidine), anti-arrhythmic medicines (like amiodarone, quinidine), antibiotics (like clindamycin), and painkillers (like acetylsalicylic acid, aminosalicylic acid, diflunisal), antidepressants (like citalopram), HIV protease inhibitors (like ritonavir, nelfinavir), protease inhibitors (like indinavir, nelfinavir, ritonavir, saquinavir), barbiturates (like phenobarbital), antacids (like magnesium hydroxide), and proton pump inhibitors (like omeprazole). Before using any prescription or over-the-counter medications, you must consult your doctor.

Do not use Nicoumalone / Acenocoumarol if you have an allergic reaction (hypersensitivity) to any of its components. Do not take Nicoumalone / Acenocoumarol if you consume St John's wort plant, cranberry juice, or ginkgo biloba. Due to a possible interaction, Nicoumalone / Acenocoumarol may increase the chance of serious adverse effects such as the risk of bleeding. We recommend that you consult a doctor as soon as possible.

No, stopping it suddenly may result in cardiovascular problems such as heart attack and stroke. Therefore, you should consult your physician before discontinuing your Nicoumalone / Acenocoumarol therapy.

Yes, it is a blood thinner, therefore taking it can raise your risk of bleeding. Therefore, please take precautions while shaving, trimming fingernails or toenails, or using other sharp tools to prevent bleeding.

No, it is unlikely to affect fertility in either men or women. However, there is currently insufficient evidence to justify any clear conclusion. Consult your doctor for the most accurate information.

No, the use of Nicoumalone / Acenocoumarol will not lead to the development of any habitual actions. There have been no reports that withdrawal symptoms may appear when it is stopped. If you have any problems, you should consult your doctor.

Yes, it causes the thinning of the blood. It prevents the formation of blood clots by reducing the chances of platelets binding.

Terms & Conditions

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