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Nepafenac + Oxychloro Complex

Uses of Nepafenac + Oxychloro Complex

  • The primary use of the ophthalmic preparation of Nepafenac + Oxychloro Complex is the management of pain and inflammation associated with cataract surgery. It belongs to the group of NSAIDs and antimicrobial agents used in ophthalmic preparations.

Side effects of Nepafenac + Oxychloro Complex

  • Increased intraocular pressure

  • Sensation of foreign body in eyes

  • Eye itching

  • Blurred vision

  • Headache

How Nepafenac + Oxychloro Complex works

  • Nepafenac + Oxychloro Complex is a non-steroidal anti-inflammatory and antimicrobial combination.

  • Nepafenac is a prodrug. Upon application, it quickly penetrates the cornea and is converted into its active form, amfenac, by enzymes present in the eye tissues. Amfenac works by blocking cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes that are responsible for producing prostaglandins, which cause inflammation and pain.

  • By inhibiting the production of these prostaglandins, Nepafenac effectively reduces inflammation and pain in the eye, making it useful for managing ocular discomfort associated with certain surgical procedures like cataract surgery.

  • Oxychloro Complex serves as a mild, non-sensitising preservative. It is designed to break down into components that mimic natural tears, such as sodium chloride and water, thereby minimising irritation and enhancing the comfort of the eye drops.

Certified content

Written By

docImg
Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Divya Chauhan
Dr. Divya Chauhan Medical Writer & Reviewer| 6 years

BAMS, APG, PG

Expert Advice

Dosage Forms Available

  • Nepafenac + Oxychloro Complex is available as a sterile ophthalmic suspension designed for topical application to the eye.

Age and Dose Restrictions

  • This combination is intended for use in adults and children above 10 years of age.

Contraindications

  • This combination is contraindicated in patients with known hypersensitivity to any of the components in the formulation.

  • It is also contraindicated in patients who have previously shown hypersensitivity reactions to other non-steroidal anti-inflammatory drugs (NSAIDs).

Other Medications to Avoid

  • This combination may interact with topical corticosteroids (e.g., dexamethasone, prednisolone), anticoagulants (like warfarin), and any medications known to prolong bleeding time (such as aspirin).

Overdose and Missed Dose

  • An overdose may result in increased local side effects like eye redness, burning, or stinging sensation. Do not panic, rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • If you miss a dose of this combination, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and return to your normal dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For those experiencing eye irritation or discomfort, try applying a warm compress to your eyes.

  • If you experience eye dryness, blinking more frequently or using over-the-counter artificial tears might help.

Use in Driving and Operating Machinery

  • This combination may cause temporary blurred vision. Therefore, patients are advised to avoid driving or operating heavy machinery until their vision has cleared.

Use in Pregnancy and Lactation

  • The safety of Nepafenac + Oxychloro Complex during pregnancy and lactation has not been fully established. Therefore, it should be used only when clearly needed and prescribed by a doctor.

Caution in Other Conditions

  • Caution should be taken when using Nepafenac + Oxychloro Complex in patients with pre-existing conditions that affect the eye's normal healing capabilities such as rheumatoid arthritis, diabetes mellitus, or ocular surface diseases.

Special Dietary and Lifestyle Recommendations

  • Limit your exposure to sunlight and always protect your eyes with UV-protective sunglasses when outside.

  • Do not wear contact lenses during the treatment period with this combination unless advised by your doctor.

  • Maintain good eye hygiene to prevent any potential infections.

Frequently asked questions

No, it is not a steroid. It is a combination of an NSAID and an antimicrobial agent used in ophthalmic preparations.

It is not known to directly affect sleep. However, if you experience any changes in your sleep patterns after starting this combination, consult your doctor.

It is not known to have any effect on fertility. If you have concerns regarding fertility issues or are planning to conceive, consult your doctor.

No, it is typically not available as an over-the-counter medication. It is usually prescribed by a doctor.

Yes, but always follow doctor's instructions on how often and how long to use this combination.

Nepafenac + Oxychloro Complex typically starts working within 30 mins to 1 hour. The exact time may vary depending on the individual and the condition being managed.

The best time to take Nepafenac + Oxychloro Complex depends on the specific condition being treated. Follow the prescribed dosage and administration instructions.

Terms & Conditions


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