Nepafenac
Uses of Nepafenac
The primary use of Nepafenac is to manage pain and inflammation associated with cataract surgery. It belongs to the group of non-steroidal anti-inflammatory medicines specifically designed for ophthalmic use.
Side effects of Nepafenac
Blurry vision
Feeling as if something is in your eye
Elevated pressure inside the eye
Sticky feeling in the eye
How Nepafenac works
Nepafenac is a non-steroidal anti-inflammatory drug (NSAID).
When used as an eye drop, it penetrates the cornea and gets converted into an active metabolite called amfenac by enzymes in the eye.
Amfenac works by inhibiting an enzyme called cyclooxygenase, which plays a crucial role in producing prostaglandins. Prostaglandins are substances that cause inflammation and pain.
By slowing down the production of these prostaglandins, Nepafenac effectively reduces inflammation and pain in the eye.
Certified content
Written By
MD Ayurveda
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Nepafenac is administered as eye drops or ophthalmic suspension.
Age and Dose Restrictions
Nepafenac is meant for adults and children over 10 years of age.
Contraindications
Do not use this medicine if you are allergic to it or any other ingredients in the eye drops, if you are allergic to other NSAIDs, if you have had complicated eye surgeries, have conditions affecting your cornea, or have had multiple eye surgeries in the past. If you also show any sign of damage to the epithelium (the outer layer) of your cornea, you should stop using Nepafenac immediately.
Other Medications to Avoid
Nepafenac can interact with topical corticosteroids (such as prednisolone and dexamethasone).
Overdose and Missed Dose
In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
If you forget to use Nepafenac at the scheduled time, put a drop in your eye as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double up on doses.
Management of Side Effects
Most side effects of Nepafenac are temporary and generally harmless. They usually go away once you stop using this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Use in Driving and Operating Machinery
Nepafenac can cause side effects such as blurred vision. If you experience this, do not drive or operate machinery until your vision is clear again.
Use in Pregnancy and Lactation
If you are pregnant, you should only use Nepafenac if your doctor believes the benefits outweigh the risks. This is because Nepafenac has been found to cross the placenta in animal studies. Furthermore, if you are breastfeeding, use this medication with caution and only if your doctor recommends it.
Caution in Other Conditions
If you have diabetes or rheumatoid arthritis, you should use Nepafenac with caution.
Special Dietary and Lifestyle Recommendations
Practice good hygiene, especially when handling the eye drops, to avoid contamination.
Frequently asked questions
How long does it take for Nepafenac to work?
It usually begins to relieve symptoms soon after you start using it, but the exact time can vary depending on the individual and the condition being managed.
Can I wear contact lenses while using Nepafenac?
No, it is not recommended to wear contact lenses while using this medication.
How long can I use Nepafenac?
The duration of treatment with Nepafenac should be determined by your doctor. It is typically used for 2 weeks following cataract surgery.
Can I use Nepafenac for other eye conditions?
It is not recommended to use Nepafenac for any condition other than what it has been prescribed for by your doctor.
Can I buy Nepafenac over the counter?
No, it is a prescription medication, and it should be used under the guidance of a doctor.
What should I do if Nepafenac gets into my mouth or nose?
If this happens, simply rinse with water. If you experience any adverse symptoms, please consult your doctor.
Can I use Nepafenac if I have dry eyes?
Yes, but you should consult your doctor first, as it may cause further irritation.
Nepafenac in other salts
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