Home/Drugs By Ailments / Midodrine

Midodrine

Uses of Midodrine

  • Midodrine is primarily used to manage orthostatic hypotension (blood pressure that occurs when standing up from sitting or lying down) and is known as an alpha-1 adrenergic receptor agonist.

  • It is also used in patients with autonomic dysfunction or neurogenic orthostatic hypotension caused by conditions like Parkinson's disease, multiple system atrophy, or pure autonomic failure.

Side effects of Midodrine

  • High blood pressure when lying down

  • Goosebumps

  • Itching

  • Chills

  • Frequent urination

How Midodrine works

  • Midodrine is an alpha-1 adrenergic receptor agonist.

  • Its primary function is to increase blood pressure in patients suffering from orthostatic hypotension, a condition characterised by a significant drop in blood pressure when standing up from sitting or lying down. This is achieved through its active metabolite, desglymidodrine, which acts upon alpha-1 adrenergic receptors.

Certified content

Written By

docImg
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • Midodrine is available for use via the oral route in the form of tablets.

Age and Dose Restrictions

  • Midodrine is meant for adults.

Contraindications

  • Midodrine should not be used in patients with certain medical conditions like high blood pressure when they are lying down, those who have an allergy to Midodrine or any of its components, and those who are already taking some types of vasoconstrictor agents or monoamine oxidase (MAO) inhibitors, substances that can interact with Midodrine and potentially cause harmful effects.

Other Medications to Avoid

  • This medicine may interact with antihistamines (e.g., diphenhydramine), anticonvulsants (e.g., pregabalin), and antipsychotics (e.g., quetiapine).

Overdose and Missed Dose

  • If an overdose of Midodrine occurs, it can lead to symptoms such as a rapid heartbeat, increased blood pressure, and possibly blurred vision. In case of a suspected overdose, contact your doctor immediately for advice.
  • If you miss a dose of Midodrine, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drink plenty of fluids to help manage any problems with urination.
  • Keep your skin moisturised to help alleviate itching.
  • Wear appropriate clothing for the weather to help manage chills.

Use in Driving and Operating Machinery

  • Midodrine can cause side effects such as dizziness or light-headedness. Due to this, it may affect your ability to drive or operate machinery. If you experience these side effects, it is recommended to avoid driving or operating heavy machinery until you feel well enough.

Use in Pregnancy and Lactation

  • It is advised that pregnant women and breastfeeding mothers use Midodrine only if the potential benefits outweigh the potential risks. Please consult your doctor before using Midodrine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Midodrine should be used with caution in patients with severe heart disease, acute kidney injury, urine retention problems, pheochromocytoma (a rare tumour that causes high blood pressure), or thyrotoxicosis (an overactive thyroid gland).
  • Elderly patients and those with liver or kidney problems should use Midodrine with caution. In these cases, dose adjustments may be necessary.

Special Dietary and Lifestyle Recommendations

  • While taking Midodrine, it is important to maintain a hygienic lifestyle to manage your underlying condition effectively.

Frequently asked questions

Midodrine is a prescription medication. It must be used under the guidance of a doctor.

Yes, Midodrine can be taken with or without food. However, it should not be taken within 3-4 hours of bedtime.

After taking Midodrine, its active metabolite, desglymidodrine, reaches its peak levels in your body within an hour. The effects start showing up in this timeframe.

Weight gain is not a known side effect of Midodrine. However, individual responses to medication can vary. If you notice significant weight changes while taking Midodrine, consult your doctor.

Mood changes are not a common side effect of Midodrine. If you experience significant mood changes while using this medication, consult your doctor.

There are no natural substitutes for Midodrine that can provide the same effects. Always consult your doctor before trying any alternative treatments.

Do not stop taking Midodrine without consulting your doctor first, as this may lead to withdrawal symptoms or a return of your previous symptoms.

Terms & Conditions

Available medicines for MIDODRINE
Xidorin Tablet 20
Xidorin Tablet 20
Sun Pharmaceutical Industries Ltd
Pack of 20 Units
₹820.00
MRP ₹1000.00
18.00% OFF
Midgeo Tablet 10
Midgeo Tablet 10
Centaur Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹198.08
MRP ₹241.56
18.00% OFF
Midorise 5 Tablet 10
Midorise 5 Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹627.30
MRP ₹765.00
18.00% OFF
Gutron 2.5mg Tablet 20
Gutron 2.5mg Tablet 20
Cipla Ltd.
Pack of 20 Units
₹1236.75
MRP ₹1455.00
15.00% OFF
Midodrive Tablet 20
Midodrive Tablet 20
Sun Pharma Laboratories Ltd.
Pack of 20 Units
₹899.54
MRP ₹1097.00
18.00% OFF
Cipmido 5mg Tablet 10
Cipmido 5mg Tablet 10
Cipla Ltd.
Pack of 10 Units
₹546.67
MRP ₹666.67
18.00% OFF
Midgeo 5 Tablet 10
Midgeo 5 Tablet 10
Centaur Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹451.00
MRP ₹550.00
18.00% OFF
Xidorin 5 Tablet 10
Xidorin 5 Tablet 10
Sun Pharmaceutical Industries Ltd
Pack of 10 Units
₹680.60
MRP ₹830.00
18.00% OFF

Subscribe

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.

playstoreIcon

Contact Us

Our customer representative team is available 7 days a week from 9 am - 9 pm.


v3.4.16

copyright2024 - Truemeds | All rights reserved

Our Payment Partners

paymentPartnerpaymentPartnerpaymentPartnerpaymentPartnerpaymentPartner
paymentPartnerpaymentPartnerpaymentPartnerpaymentPartner