Micronised Purified Flavonoid Fraction
Uses of Micronised Purified Flavonoid Fraction
The primary use of Micronised Purified Flavonoid Fraction is the management of venous diseases such as chronic venous insufficiency, lymphedema, and haemorrhoids. It belongs to the group of medicines known as phlebotropics.
Secondary uses of MPFF include the management of conditions such as venous ulcers, superficial vein thrombosis, diabetic retinopathy, melasma, and rosacea.
Side effects of Micronised Purified Flavonoid Fraction
Abdominal pain
Diarrhoea
Dizziness
Headache
Rash
How Micronised Purified Flavonoid Fraction works
Micronised Purified Flavonoid Fraction is a phlebotropic medicine.
It works by enhancing the effect of norepinephrine on vein walls, which increases venous tone, meaning it strengthens the veins and helps them function better.
It also augments the frequency and intensity of lymphatic contractions, thus improving lymphatic drainage. This means it helps excess fluid move out of your tissues more efficiently.
Furthermore, it reduces capillary hyperpermeability, which decreases fluid leakage into tissues. This action helps to reduce tissue swelling.
In addition, it inhibits inflammatory mediators like prostaglandins and free radicals, reducing inflammation in affected areas.
It also provides antioxidant protection to blood vessels and valves, shielding them from damage by harmful substances in the body.
Together, these actions provide relief from venous hypertension, improve microcirculatory flow (the flow of blood through small blood vessels), and manage trophic disorders (conditions affecting nourishment to parts of your body), as seen in conditions like chronic venous disease.
Certified content
Written By
BDS, MDS
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Micronised Purified Flavonoid Fraction is available for oral consumption in the form of tablets, capsules, and sachets, which provide an alternative method of administering the medicine in a dissolvable form.
Age and Dose Restrictions
This medicine is designed for use in the adult population.
Contraindications
Micronised Purified Flavonoid Fraction is contraindicated in individuals with hypersensitivity to any of its components.
Other Medications to Avoid
This medicine may interact with anticoagulants (such as warfarin and heparin) and antiplatelet agents (like aspirin and clopidogrel).
Overdose and Missed Dose
An overdose of Micronised Purified Flavonoid Fraction may lead to increased severity of side effects such as gastrointestinal discomfort or headache. If suspected, seek immediate medical attention.
If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage mild gastrointestinal upset, consider taking the medication with meals.
If experiencing dizziness or headaches, ensure adequate hydration by drinking plenty of water.
Use in Driving and Operating Machinery
Micronised Purified Flavonoid Fraction may cause dizziness in some individuals. It is advised to avoid driving or operating heavy machinery if you experience such symptoms after taking this medicine.
Use in Pregnancy and Lactation
The safety of Micronised Purified Flavonoid Fraction during pregnancy or lactation has not been established. It is advised to consult your doctor before using this medication if you are pregnant or breastfeeding.
Caution in Other Conditions
Individuals with kidney or liver conditions should use Micronised Purified Flavonoid Fraction with caution. No dose adjustment is required specifically, but monitoring for side effects may be prudent.
Special Dietary and Lifestyle Recommendations
Incorporate a diet high in fibre to help manage symptoms like leg heaviness and swelling associated with venous diseases. Foods like whole grains, fruits, and vegetables can be beneficial.
Regular gentle exercise, such as walking, can improve circulation and help manage symptoms of chronic venous insufficiency.
Elevate your legs when possible to reduce leg swelling and discomfort associated with venous diseases.
Avoid wearing tight clothing that could restrict blood flow around your waist or legs.
Frequently asked questions
Is Micronised Purified Flavonoid Fraction a steroid?
No, it is not a steroid. It belongs to the group of phlebotropic medications and is mainly used for managing venous diseases.
Do I need a prescription to take Micronised Purified Flavonoid Fraction?
Yes, it is a medication that you need a prescription for. It is not typically available over the counter.
Is Micronised Purified Flavonoid Fraction safe for long-term use?
Yes, it is generally safe for long-term use. However, the duration of treatment should be determined by your doctor based on your specific condition and response to the medication.
Can Micronised Purified Flavonoid Fraction affect my mood or emotions?
There is no evidence suggesting that this medicine directly affects mood or emotions. However, it is always recommended to consult your doctor if you experience any unusual changes in mood while taking this medicine.
How soon can I expect to see results from taking Micronised Purified Flavonoid Fraction?
Symptom relief usually begins within 2-4 weeks of starting treatment with this medicine. Maximum benefits are seen after 2-6 months of consistent use.
Are there any diet restrictions while taking Micronised Purified Flavonoid Fraction?
No specific diet restrictions are mentioned in relation to taking this medicine. However, it is advisable to maintain a healthy, balanced diet while on medication.
Can people with diabetes take Micronised Purified Flavonoid Fraction?
Yes, it can be safely used in diabetic patients with venous disorders. It may even contribute to the management of diabetic retinopathy and neuropathy.
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