Micafungin is predominantly used for managing serious fungal infections caused by Candida and Aspergillus species. It belongs to the echinocandin class of antifungal medicines.
It is also used off-label for other invasive fungal infections, particularly when other antifungal medicines are not suitable or effective.
Diarrhoea
Nausea
Vomiting
Pyrexia (Fever)
Headache
Micafungin is an echinocandin antifungal medicine. It acts by inhibiting an enzyme known as 1,3-beta glucan synthase. This enzyme is vital for the synthesis of beta-1,3-glucan, a significant structural component of fungal cell walls. By disrupting the creation of glucan polymers, Micafungin damages fungal cell walls. This leads to osmotic instability and death of the fungal cells.
Doctor of Medicine
BMS, FMC, MD Resident
Micafungin is available as a sterile, lyophilized powder for reconstitution. It is administered intravenously, meaning it is given as an injection directly into a vein.
This medicine can be given to adults and children. However, for paediatric patients, the age of use starts from 4 months onwards.
Micafungin is contraindicated in patients with hypersensitivity to the active substance itself, any component of the formulation, or other echinocandins.
Micafungin may interact with immunosuppressants (such as sirolimus), calcium channel blockers (such as nifedipine) and other antifungal medicines (like itraconazole).
Overdose of Micafungin could potentially lead to severe adverse reactions. If you suspect an overdose has occurred, consult your doctor immediately.
If you happen to miss getting a dose of the medication, contact your doctor immediately.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drink plenty of fluids to manage side effects such as diarrhoea and vomiting.
Resting and staying hydrated can help manage symptoms like headache and pyrexia.
This medicine does not directly affect the ability to drive or operate machinery. However, some of its side effects, like headache or nausea, might indirectly impair your ability to focus.
Use of Micafungin during pregnancy and lactation should be done under the advice of a doctor, as potential risks need to be carefully weighed against the benefits.
Caution should be exercised in patients with moderate hepatic impairment. It is not recommended for use in patients with severe hepatic impairment.
Maintaining a balanced diet, rich in nutrients can support your body's immune system and enhance its ability to fight off infections.
Ensure good personal hygiene to reduce the risk of fungal infections.
Try to avoid places or situations that might expose you to fungal spores, particularly if you have a weakened immune system.
Regular hand washing and keeping your living and workspaces clean can also help prevent fungal infections.
Frequently asked questions
Yes, Micafungin can also be used off-label to manage other invasive fungal infections, particularly when other antifungal medicines are not suitable or effective.
Micafungin is an injectable medicine that is usually administered in a hospital or clinic setting by a doctor. The timing of the injection will be determined by your healthcare team based on your specific needs and conditions.
Micafungin starts working immediately once administered into the body. However, it may take a few days before the symptoms of the infection improve. The full course of treatment should be completed for complete recovery.
Yes, it is safe to administer Micafungin as prescribed by your doctor. The dosage and duration of treatment depend on the type and severity of the infection.
Micafungin is not directly associated with affecting fertility. If you have concerns about this, please consult your doctor for advice.
Micafungin is not associated with affecting sleep. However, individual reactions to medicine can vary, so if you experience any changes in your sleep pattern while using this medicine, please consult your doctor.
No, Micafungin is not a steroid. It belongs to a class of medicines known as echinocandins, which are antifungal agents.
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