Methylcobalamin
VITAMINUses of Methylcobalamin
- Methylcobalamin is used to treat vitamin B12 deficiency, which can cause megaloblastic anemia and nerve damage.
- It helps manage peripheral neuropathy, especially in diabetes, supports brain health, and alleviates symptoms in neurological disorders like Alzheimer's and multiple sclerosis.
- It aids in proper brain and nerve function and red blood cell production.
Side effects of Methylcobalamin
- Nausea
- Diarrhoea
- Loss of appetite
- Vomiting
- Headache
How Methylcobalamin works
- Methylcobalamin is a form of vitamin B12 that helps support the normal functioning of the nervous system. It plays a role in the regeneration and repair of damaged nerves. It helps alleviate neuropathic pain by aiding in the healing and restoration of affected nerves. It is considered the active form of vitamin B12 because it can be directly used by the body without any further modification.
- It is also essential for synthesising DNA and RNA, facilitating the maturation of red blood cells. By supporting the formation of healthy blood cells, Methylcobalamin effectively treats megaloblastic anaemia, ensuring the normalisation of blood cell production.
- Methylcobalamin is essential for the production of myelin, a substance that sheaths nerve fibers and helps them transmit signals properly. A deficiency of methylcobalamin can lead to nerve damage and symptoms such as numbness, tingling, and pain.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available for Methylcobalamin
- Methylcobalamin can be taken orally (tablet), intramuscularly, or intravenously (injection).
Age And Dosage Restrictions for Methylcobalamin
- It can be used by adults and children.
Contraindications of Methylcobalamin
- It is contraindicated in patients with a history of hypersensitivity to Methylcobalamin or Vitamin B12.
Other Medications To Avoid With This Medicine
- Avoid taking antibiotics (neomycin), antituberculosis agents (aminosalicylic acid), stomach acid reducers (cimetidine), antigout medication (colchicine), and oral contraceptives with Methylcobalamin. These medications may alter the safety and effectiveness of Methylcobalamin.
Medications To Avoid With Methylcobalamin
- If you take an overdose of this medication by accident and experience worsening of any of the symptoms, please consult your doctor. It is advised to adhere to the prescribed dose.
- If you miss a dose of this medication, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.
Management Of Side Effects
- Take it with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- This medication is unlikely to impair the mental alertness or coordination required while driving.
Use In Pregnancy And Lactation
- Caution is advised in pregnant and breastfeeding women.
Special Dietary And Lifestyle Recommendation
- Include foods high in B vitamins (such as leafy greens, legumes, and fortified cereals) as they support nerve health.
- For those with neuropathy, manage blood sugar levels through a balanced diet, regular exercise, and adherence to prescribed medications. Stable blood sugar helps prevent further nerve damage.
- Consume foods high in folate, such as leafy green vegetables, legumes, and fortified grains, to complement vitamin B12 in supporting red blood cell production and preventing megaloblastic anaemia.
- Avoid smoking and limit alcohol consumption. It can impair circulation and potentially worsen nerve damage.
Frequently asked questions
1. Does Methylcobalamin increase blood sugar levels?
No, it does not increase blood sugar levels.
2. Is Methylcobalamin a habit-forming medicine?
No, it is not habit-forming and is generally safe when used as directed.
3. Is Methylcobalamin available over the counter, or do I need a prescription?
This medication usually requires a prescription and is unavailable over the counter.
4. Does Methylcobalamin affect fertility?
This medication is not known to impact fertility.
5. Does Methylcobalamin cause dry mouth?
No, this medication is not commonly associated with causing dry mouth.
6. Is it safe to drink alcohol while having Methylcobalamin?
It is generally advisable to avoid alcohol while taking this medication, as alcohol may affect its absorption and aggravate the side effects
7. Does Methylcobalamin cause sleep?
No, this medication does not directly cause sleep-related effects, but addressing vitamin B12 deficiency may indirectly improve sleep quality.
8. What is the best time to take Methylcobalamin?
The best time to take this medicine is typically as your doctor prescribes, often recommended as part of a regular dosing schedule.
9. How often is Methylcobalamin injection taken?
This injection is typically administered intramuscularly one to three times a week. The frequency may change based on individual needs, and the doctor may adjust the injection schedule during treatment.
10. Does Methylcobalamin improve weakness?
This medication can help improve weakness, especially when related to conditions like peripheral neuropathies or megaloblastic anaemia. Its role in nerve health and red blood cell formation contributes to addressing underlying deficiencies, potentially alleviating weakness over time.
11. Is Methylcobalamin used for nerve pain?
Yes, this medication is commonly used for nerve pain, particularly in conditions like peripheral neuropathies.
12. Is Methylcobalamin a painkiller?
This medication is not classified as a painkiller or analgesic in the traditional sense. However, its primary purpose is to help keep nerve cells healthy and work appropriately, but it is not specifically a pain killer.
13. Does Methylcobalamin consumption cause weight gain?
Methylcobalamin consumption typically does not cause weight gain. It is a form of vitamin B12, primarily used to treat vitamin B12 deficiency and support nerve health, without commonly affecting body weight.
14. How long does Methylcobalamin stay in your system?
Methylcobalamin stays in your system for about 48 hours. However, this duration can vary depending on factors such as your metabolic rate and overall health.
15. Why can’t I get sufficient vitamin B12 from my diet?
You may not get sufficient vitamin B12 from your diet if you follow a vegan or vegetarian diet, as B12 is mostly found in animal products. Additionally, certain medical conditions and medications can interfere with B12 absorption from food.
16. Why might vegetarians or vegans struggle to get sufficient vitamin B12 from their diet?
Vegetarians and vegans might struggle to get sufficient vitamin B12 because this vitamin is primarily found in animal products like meat, dairy, and eggs. Plant-based foods do not naturally contain vitamin B12, so those following a vegetarian or vegan diet need to rely on fortified foods or supplements to meet their nutritional needs.
17. How does methylcobalamin affect the brain?
Methylcobalamin, a form of vitamin B12, supports brain health by aiding in the production of myelin, the protective covering of nerve fibers. It helps maintain proper neurological function and may improve symptoms of neurological disorders, cognitive function, and mood by supporting neurotransmitter synthesis and reducing homocysteine levels.
Methylcobalamin in other salts
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