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Metformin + Teneligliptin

ANTIDIABETIC

Uses of Metformin + Teneligliptin

  • Metformin + Teneligliptin Hydrochloride are used together to treat type 2 diabetes mellitus, also known as non-insulin-dependent diabetes or adult-onset diabetes. 
  • Teneligliptin helps regulate blood sugar by enhancing the body's natural insulin production, while Metformin improves insulin sensitivity and reduces glucose production in the liver. 
  • This combination helps control blood sugar levels effectively, especially when combined with diet and exercise.

Side effects of Metformin + Teneligliptin

  • Hypoglycemia 
  • Constipation
  • Fatigue 
  • Headache
  • Dizziness
  • Bloating
  • Abdominal discomfort
  • Nausea
  • Vomiting
  • Loss of appetite

How Metformin + Teneligliptin works

  • Metformin and Teneligliptin are oral antihyperglycemic medicines.
  • Metformin, a biguanide, reduces glucose production in the liver, enhances insulin sensitivity in muscle cells, and slows glucose absorption in the intestines, helping to lower blood sugar levels in type 2 diabetes.
  • Teneligliptin inhibits DPP-4, prolonging incretin hormones' action, which increases insulin secretion and lowers glucagon levels, resulting in better blood sugar control.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Metformin and Teneligliptin can be combined orally (tablet).

Age And Dose Restrictions 

  • This combination is not intended to be used by children. 

Contraindications 

  • This combination is contraindicated in patients with a history of hypersensitivity to Metformin and Teneligliptin.

Medications To Avoid With This Drug

  • Avoid taking antifungals (ketoconazole), antidepressants, antihypertensives, steroids, diuretics, thyroid medications, corticosteroids, phenothiazines, estrogens, oral contraceptives, anticonvulsants (phenytoin), and antiepileptics (ranolazine). These medications may alter the safety and effectiveness of Metformin and Teneligliptin.

Overdose And Missed Dose

  • Overdose can cause hypoglycaemia and lactic acidosis. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of Metformin and Teneligliptin, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • Take this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. To combat hypoglycemia, eat or drink a source of sugar such as fruit juice, candy, crackers, raisins, or non-diet soda. Once your blood sugar stabilises, have a balanced snack or meal to prevent another drop. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • Metformin and Teneligliptin can make you feel dizzy. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination till you know how the combination affects you.

Use In Pregnancy And Lactation

  • Caution is advised while taking this combination during pregnancy. This combination is not recommended for breastfeeding.

Caution In Other Conditions

  • Caution is advised in older adults and patients with diabetic ketoacidosis, pancreatitis, joint pain, irregular heartbeat, hypoglycaemia (low blood sugar), vitamin B12 deficiency and kidney and liver impairment.

Special Dietary And Lifestyle Recommendation

  • Incorporate foods with low glycemic index, such as green leafy vegetables, whole grains, berries, citrus fruits, chia seeds, bitter gourd and extra virgin olive oil.
  • Engage in regular physical activity, which can help improve insulin sensitivity and blood sugar control.
  • Watch your sodium intake and not exceed 5g daily to avoid heart conditions with diabetes.
  • Monitor your blood sugar levels regularly and stay connected with your doctor to adjust your treatment plan.

Frequently asked questions

Metformin and Teneligliptin typically show their effects within a few hours after ingestion. However, individual responses may vary. 

The combination of Metformin and Teneligliptin is not habit-forming and is generally safe when used as directed.

The use of this combination is not known to impair female fertility.

The combination of Metformin and Teneligliptin usually requires a prescription and is not available over the counter.

The best time to take this combination is typically with your meal to reduce the risk of stomach upset. However, always follow your doctor’s specific instructions while prescribing this tablet.

This combination is generally considered safe when used as prescribed and monitored by a doctor. However, individuals with diabetic ketoacidosis, pancreatitis, joint pain, irregular heartbeat, and hypoglycaemia (low blood sugar) should consult a doctor before taking this tablet.

This combination may lead to modest weight loss in some individuals. Consult your doctor if you have any concerns.

This combination may cause constipation as a side effect. However, individual responses may vary. If you have persistent constipation while taking this combination, consult your doctor.

This combination is not recommended to manage type 1 diabetes. It is used only for type 2 diabetes.

The combination of Metformin and Teneligliptin typically has a low risk of causing hypoglycemia (low blood sugar) when used alone. However, the risk may increase if taken with other antidiabetic medications, insulin, or if meals are skipped.

Yes, Metformin, when combined with Teneligliptin, can potentially cause lactic acidosis, a rare but serious condition. This risk is higher in patients with kidney problems, liver disease, or excessive alcohol consumption.

Yes, long-term use of Metformin, including in combination with Teneligliptin, can lead to Vitamin B12 deficiency. Regular monitoring and supplementation, if necessary, may be recommended by your healthcare provider.

Terms & Conditions


Available medicines for METFORMIN + TENELIGLIPTIN
Dynaglipt M Tablet 10
Dynaglipt M Tablet 10
Mankind Pharmaceuticals Ltd.
Pack of 10 Units
₹108.15
MRP ₹131.89
18.00% OFF
Tenepla M 1000 Tablet 10
Tenepla M 1000 Tablet 10
Cipla Ltd.
Pack of 10 Units
₹79.59
MRP ₹159.50
50.10% OFF
Tenlimac M 500 Tablet 15
Tenlimac M 500 Tablet 15
Macleods Pharmaceuticals Pvt.ltd
Pack of 15 Units
₹156.21
MRP ₹190.50
18.00% OFF
Tendia M Tablet 15
Tendia M Tablet 15
Eris Lifesciences Ltd
Pack of 15 Units
₹213.21
MRP ₹260.01
18.00% OFF
Tenepla M 500 Tablet 10
Tenepla M 500 Tablet 10
Cipla Ltd.
Pack of 10 Units
₹76.85
MRP ₹154.00
50.10% OFF
Zita Met Plus 20mg/500mg Tablet 15
Zita Met Plus 20mg/500mg Tablet 15
Glenmark Pharmaceuticals Ltd.
Pack of 15 Units
₹236.16
MRP ₹288.00
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Axegliptin M 500 Tablet 10
Axegliptin M 500 Tablet 10
Ajanta Pharma Ltd
Pack of 10 Units
₹74.35
MRP ₹149.00
50.10% OFF
Tenefit M Tablet 15
Tenefit M Tablet 15
Systopic Laboratories Ltd-mem
Pack of 15 Units
₹124.23
MRP ₹151.50
18.00% OFF

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