Loteprednol + Moxifloxacin is primarily used to manage bacterial eye infections with associated inflammation. It belongs to the group of corticosteroids and fluoroquinolone antibiotics.
Secondary uses of this combination include its prophylactic use in eye surgery to prevent postoperative bacterial infections and manage ocular inflammatory conditions such as blepharitis, episcleritis, scleritis, keratitis, iritis, and cyclitis.
Ocular discomfort (e.g., burning or stinging)
Photophobia (sensitivity to light)
Conjunctival hyperaemia (redness of the white part of the eye)
Dry eye
Loteprednol + Moxifloxacin is an ophthalmic medication combination.
Loteprednol is a corticosteroid. It reduces swelling and inflammation in the eyes by suppressing the body's immune response and inhibiting pro-inflammatory signals, thus reducing redness and pain that can occur with eye infections.
Moxifloxacin, a fluoroquinolone antibiotic, kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops DNA replication and repair in bacterial cells, thus causing them to die.
Doctor of Medicine
BMS, FMC, MD Resident
Loteprednol + Moxifloxacin is available as an ophthalmic suspension to be used via the topical route. It is instilled in the form of eye drops directly into the affected eye(s).
Loteprednol + Moxifloxacin is meant for adult patients and children who are above two years of age.
Loteprednol + Moxifloxacin is contraindicated in patients with known hypersensitivity to either Loteprednol, Moxifloxacin, or other quinolones.
Additionally, it is contraindicated in most viral infections of the cornea and conjunctiva, mycobacterial infections of the eye, and fungal diseases of ocular structures.
Loteprednol + Moxifloxacin may interact with other topical ophthalmic medications, such as eye drops or ointments containing different active ingredients. The combination may also interact with P-glycoprotein efflux transporter inhibitors (such as ketoconazole, itraconazole, erythromycin, and verapamil).
In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
If you miss a dose of this medicine, use it as soon as you remember. However, avoid doubling the dose to make up for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help manage headaches and dry mouth.
Resting or closing your eyes for a few moments could help manage burning/stinging/irritation in the eyes.
Loteprednol + Moxifloxacin may cause blurred vision or other visual disturbances. It is advised not to drive a vehicle or operate heavy machinery unless you know how this medicine affects you.
Please consult your doctor before using this medicine if you are pregnant or breastfeeding.
Caution is advised for patients with glaucoma, as prolonged use of corticosteroids like loteprednol may result in increased intraocular pressure.
Maintain good eye hygiene to prevent bacterial infections; clean your hands regularly and avoid touching your eyes unnecessarily.
Wear protective eyewear outdoors to prevent dust particles or other foreign bodies from entering the eyes.
Loteprednol + Moxifloxacin in other salts
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