Losartan + S-amlodipine
Uses of Losartan + S-amlodipine
Losartan + S-Amlodipine is primarily used to manage hypertension, or high blood pressure. It belongs to the group of angiotensin II receptor blockers (ARBs) and calcium channel blockers (CCBs).
It also helps in reducing the risk of stroke in hypertensive patients with left ventricular hypertrophy
Side effects of Losartan + S-amlodipine
Dizziness
Headache
Oedema
Fatigue
Nausea
How Losartan + S-amlodipine works
Losartan + S-Amlodipine is a combination medication that helps manage high blood pressure.
Losartan is an angiotensin II receptor blocker. It works by blocking the action of a natural substance called angiotensin II in the body, which causes blood vessels to tighten and narrow. By preventing this action, Losartan helps relax and widen the blood vessels, resulting in reduced blood pressure.
S-Amlodipine is a calcium channel blocker. It operates by inhibiting the movement of calcium into the muscle cells of the heart and blood vessels. As muscle cells need calcium to contract, S-Amlodipine's action results in these cells relaxing, leading to wider blood vessels and decreased blood pressure.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Losartan + S-Amlodipine is available in the form of tablets for oral administration.
Age and Dose Restrictions
This medication is meant for adult use. It is not recommended for children or adolescents under 18 years of age.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to either Losartan or S-Amlodipine.
It is also contraindicated in patients with severe hepatic impairment and biliary cirrhosis.
Other Medications to Avoid
Losartan + S-Amlodipine may interact with NSAIDs (such as ibuprofen and celecoxib), potassium-sparing diuretics (such as spironolactone and amiloride), and medications that inhibit CYP3A4 and P-glycoprotein, such as antifungal agents (e.g., ketoconazole, itraconazole), antibiotics (e.g., erythromycin, clarithromycin), and protease inhibitors (e.g., ritonavir, indinavir).
Overdose and Missed Dose
Overdosing on Losartan + S-Amlodipine may cause lowered blood pressure, dizziness, or fainting. If you suspect an overdose, contact your doctor immediately.
In case of a missed dose, take the medication as soon as you remember. However, if it is almost time for the next dose, skip the missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage some of the side effects like dry mouth or headaches.
Resting or lying down can help manage dizziness.
Use in Driving and Operating Machinery
This medication may cause dizziness or lightheadedness. Avoid driving or operating heavy machinery if you experience these side effects.
Use in Pregnancy and Lactation
The use of Losartan + S-Amlodipine during pregnancy or lactation should be avoided unless advised by a doctor.
Caution in Other Conditions
Patients with renal impairment or aortic and mitral stenosis should exercise caution when taking this medicine.
Special Dietary and Lifestyle Recommendations
It is recommended to follow a heart-friendly diet low in sodium and saturated fats.
Regular physical activity, such as walking or cycling, can help control blood pressure.
Limiting alcohol consumption and quitting smoking are also recommended for patients with hypertension.
Frequently asked questions
Is Losartan + S-Amlodipine a steroid?
No, Losartan + S-Amlodipine is not a steroid. It is a combination medicine that belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers (CCBs).
Does Losartan + S-Amlodipine have any effect on sleep?
Losartan + S-Amlodipine is not known to impact sleep. However, some people may experience dizziness or fatigue, which could potentially impact sleep patterns.
Will Losartan + S-Amlodipine affect fertility?
Losartan + S-Amlodipine is not known to have any adverse impact on fertility. However, if you are planning to conceive, it is recommended to consult your doctor before taking this medicine.
Are there any particular diet restrictions while taking Losartan + S-Amlodipine?
No specific diet restrictions are required. However, a healthy diet can contribute to better management of hypertension.
Is it safe to take Losartan + S-Amlodipine daily?
Yes, it is safe to take Losartan + S-Amlodipine daily as long as it is prescribed by your doctor and you adhere strictly to the prescribed dosage and timing.
How much time does Losartan + S-Amlodipine take to work?
There is no specific timeline mentioned in the literature regarding how quickly this medicine starts working. However, it is known to provide a 24-hour control of hypertension with once-daily dosing.
What is the best time to take Losartan + S-Amlodipine?
This medicine can be taken at any time of the day, with or without food. However, it is important to take it at the same time each day for optimal benefit.
Losartan + S-amlodipine in other salts
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