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Lornoxicam is a part of the non-steroidal anti-inflammatory drugs (NSAIDs) group. It works by inhibiting cyclooxygenase (COX) enzymes, mainly COX-2. This blockage decreases the production of chemicals called prostaglandins, which are responsible for pain, swelling, and fever.
Paracetamol/Acetaminophen is an analgesic and antipyretic. It impacts the central nervous system, altering the way the body feels and responds to pain. It might also block the production of prostaglandins in the central nervous system and peripheral tissues.
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Dosage Forms Available
Lornoxicam + Paracetamol/Acetaminophen is taken orally in the form of tablets and effervescent sachets.
Age and Dose Restrictions
This medicine is not recommended for use in children and adolescents below 18 years of age.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to Lornoxicam or Paracetamol/acetaminophen. It is also contraindicated for individuals with a history of asthma, urticaria, or allergic reactions triggered by aspirin or other NSAIDs. Patients with active or recurrent peptic ulcer/hemorrhage should not use this medicine. It is contraindicated for those with severe heart failure, hepatic failure, or renal failure.
Other Medications to Avoid
This combination may interact with anticoagulants (such as dabigatran and warfarin), antiplatelets (like clopidogrel and aspirin), diuretics (including furosemide and hydrochlorothiazide), lithium, methotrexate, antihypertensives (ACE inhibitors like lisinopril, ARBs like losartan, beta-blockers such as propranolol), and corticosteroids (such as betamethasone and prednisone).
Overdose and Missed Dose
An overdose of Lornoxicam + Paracetamol/Acetaminophen may lead to symptoms such as nausea, vomiting, abdominal pain, drowsiness, dizziness, and in severe cases, hepatic necrosis. Immediate medical intervention is crucial.
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If experiencing mild nausea or gastrointestinal discomfort, try taking the medication with food or a glass of milk.
For headaches or dizziness, ensure adequate hydration by drinking plenty of water.
Use in Driving and Operating Machinery
Lornoxicam + Paracetamol/Acetaminophen can cause visual disturbances and dizziness affecting your ability to drive or operate machinery. It is advised not to engage in these activities if these symptoms are experienced.
Use in Pregnancy and Lactation
Lornoxicam + Paracetamol/Acetaminophen is contraindicated during the third trimester of pregnancy. The safety of this medicine during the first two trimesters of pregnancy and during breastfeeding has not been established. Consult your doctor before using this medication if you are pregnant or breastfeeding.
Caution in Other Conditions
Caution is advised when using this medication in elderly patients due to an increased risk of adverse effects. Patients with known hepatic or renal impairment should use this medication with caution; dose adjustments may be necessary.
Special Dietary and Lifestyle Recommendations
Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to help reduce inflammation.
Stay hydrated by drinking plenty of water throughout the day.
Engage in regular physical activity appropriate to your condition to help improve mobility and reduce pain. Gentle exercises such as walking or swimming can be beneficial.
Ensure adequate rest and sleep, which are essential for the recovery of the body.
Avoid activities that exacerbate pain; listen to your body's signals and adjust activities accordingly.
Frequently asked questions
No, Lornoxicam + Paracetamol/Acetaminophen does not belong to the group of steroids. It is a combination of two different types of pain-relieving medicines.
Yes, Lornoxicam + Paracetamol/Acetaminophen can potentially cause insomnia or drowsiness in some individuals. If you experience such symptoms, please consult your doctor.
The available research data does not mention any effects of this medication on fertility. However, if you are planning to conceive, it is advised to consult your doctor before starting any new medication.
There are no specific dietary restrictions with this medication. However, it might be better to take it with meals to minimise the risk of gastrointestinal side effects.
The safety of daily usage of this medication depends on individual health conditions and the severity of pain. It should only be taken as per your doctor's advice.
The medicine generally starts working within an hour of oral administration. However, the exact time may vary depending on individual response and the type of pain being managed.
This medicine is usually not available over the counter. A valid prescription from a registered doctor is generally required to purchase this medication.
Lornoxicam + Paracetamol/acetaminophen in other salts
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