Home/Drugs By Ailments / Isosorbide-5-mononitrate / Isosorbide Mononitrate + Metoprolol Succinate

Isosorbide-5-mononitrate / Isosorbide Mononitrate + Metoprolol Succinate

Uses of Isosorbide-5-mononitrate / Isosorbide Mononitrate + Metoprolol Succinate

  • Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate is primarily used for managing angina pectoris (chest pain) and high blood pressure in patients with coronary artery disease. This medicine belongs to the group of nitrates and beta-blockers.

  • It is also used to reduce the risk of heart attacks and strokes in patients with coronary artery disease.

Side effects of Isosorbide-5-mononitrate / Isosorbide Mononitrate + Metoprolol Succinate

  • Headache

  • Dizziness or lightheadedness

  • Fatigue or weakness

  • Nausea or vomiting

  • Slow heartbeat

How Isosorbide-5-mononitrate / Isosorbide Mononitrate + Metoprolol Succinate works

  • Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate is a combination medication used for managing heart conditions.

  • Isosorbide mononitrate is a nitrate-based medicine. It works by transforming into nitric oxide in the body. This nitric oxide then helps to relax the smooth muscles within blood vessels, leading to an expanded, or vasodilated, state. This widens the arteries, increasing blood flow and oxygen supply to the heart muscle. It also lowers the heart's workload by decreasing the pressure against which the heart pumps blood.

  • Metoprolol succinate is a beta-blocker. It inhibits the action of certain natural chemicals in your body, such as adrenaline, on the heart and blood vessels. This causes a slower heartbeat and reduced blood vessel contraction. Consequently, your heart beats more slowly and with less force, lowering blood pressure and reducing the heart's oxygen demand.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate is available for oral administration in the form of extended-release tablets.

Age and Dose Restrictions

  • This medication is typically prescribed for adults of age above 18 years. It is not recommended for children or adolescents.

Contraindications

  • This combination is contraindicated for patients with severe liver or kidney disease, patients with severe heart failure, very low blood pressure, and individuals with a history of serious allergic reactions to either medicine.

Other Medications to Avoid

  • Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate may interact with other beta-blockers (like atenolol), calcium channel blockers (such as verapamil, diltiazem), certain antidepressants (such as fluoxetine), some antihypertensives (like enalapril, losartan) and diuretics (like furosemide, hydrochlorothiazide), and cardiac glycosides (such as digoxin).

Overdose and Missed Dose

  • An overdose of this combination can lead to severe hypotension and bradycardia. If you suspect an overdose, consult your doctor immediately.

  • If you miss a dose of this medication, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and resume your normal dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of fluids may help manage side effects like headache or dizziness.

  • Resting and avoiding sudden changes in posture can also help manage symptoms of lightheadedness or fatigue.

Use in Driving and Operating Machinery

  • This combination may cause dizziness or lightheadedness, affecting your ability to drive or operate machinery. Avoid these activities if you experience these symptoms.

Use in Pregnancy and Lactation

  • This medication should only be used during pregnancy or while breastfeeding if the potential benefits justify the risks. Always consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Caution is advised for patients with asthma or severe lung disease as this combination can exacerbate these conditions.

Special Dietary and Lifestyle Recommendations

  • Regularly monitoring your blood pressure and heart rate can help manage the conditions this medication is used for.

  • Reducing intake of high-sodium foods can help manage high blood pressure.

  • Regular cardiovascular exercise, as approved by your doctor, can improve overall heart health.

Frequently asked questions

No, Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate is not a steroid. Instead, it is a combination of two different types of heart medications: isosorbide mononitrate, which is a nitrate, and metoprolol succinate, which is a beta-blocker.

This combination may affect sleep in some individuals. Metoprolol, a beta blocker, can cause side effects like insomnia or vivid dreams. Isosorbide Mononitrate, used for heart-related conditions, typically doesn't affect sleep but may cause headaches, which could indirectly disturb rest. If you notice any changes in your sleep pattern, it's best to consult your doctor.

Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate is not directly associated with impacting fertility. However, if you have concerns about this issue, it is best to consult your doctor.

Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate is not associated with impacting mood. However, everyone responds differently to medications, and if you observe any changes in your mood after starting this medication, consult your doctor.

The best time to take Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate is usually determined by your doctor, based on your medical condition.

It is not advisable to suddenly stop taking this medicine without consulting your doctor, as it may worsen your angina symptoms.

The medication Isosorbide-5-Mononitrate / Isosorbide Mononitrate + Metoprolol Succinate itself does not contain any animal products. However, it is recommended to check with the manufacturer for details about the tablet coating or other excipients, which may vary.

Terms & Conditions


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