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Insulin Isophane/nph

Uses of Insulin Isophane/nph

  • Insulin Isophane/NPH is primarily used to manage blood sugar levels in individuals with diabetes mellitus. It belongs to the group of medicines known as intermediate-acting human insulins.

Side effects of Insulin Isophane/nph

  • Hypoglycaemia

  • Weight gain

  • Edema

  • Injection site reactions

How Insulin Isophane/nph works

  • Insulin Isophane/ Neutral Protamine Hagedorn Insulin (NPH) is a type of human insulin used for managing diabetes. It works by mimicking the functions of naturally produced insulin in our bodies. It binds to insulin receptors found in the liver, muscle, and fat cells, activating processes inside these cells.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Divya Chauhan
Dr. Divya Chauhan Medical Writer & Reviewer| 6 years

BAMS, APG, PG

Expert Advice

Dosage Forms Available

  • Insulin Isophane/NPH is a subcutaneous injection available in vials and prefilled pens for easy administration.

Age and Dose Restrictions

  • Insulin Isophane/NPH is typically used to manage diabetes in both adults and children. However, the exact age at which it is initiated can depend on individual clinical situations and the doctor's discretion.

Contraindications

  • Patients who have known hypersensitivity or an allergy to Insulin Isophane/NPH or any of its components should not use this medication.

  • It is also contraindicated in patients experiencing episodes of hypoglycemia, a condition where blood sugar levels are abnormally low.

Other Medications to Avoid

  • Insulin Isophane/NPH may interact with certain types of medications such as sulfonylureas (e.g., glimepiride, gliclazide), ACE inhibitors (e.g., lisinopril, ramipril), and monoamine oxidase inhibitors (MAOIs) (e.g., phenelzine, tranylcypromine).

Overdose and Missed Dose

  • An overdose of Insulin Isophane/NPH could lead to severe hypoglycemia, which may present as confusion, tremors, sweating, or even unconsciousness. In such situations, seek immediate medical attention.

  • If you miss a dose of Insulin Isophane/NPH, administer it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Never administer extra doses to compensate for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • In case of hypoglycemia, keep quick sources of sugar like candy or fruit juice handy.

  • Rotate your injection sites to prevent skin changes at the site of injection.

Use in Driving and Operating Machinery

  • Insulin Isophane/NPH may cause dizziness or blurred vision, especially if your blood sugar levels fall too low. Do not drive or operate heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

  • If you are pregnant or breastfeeding, consult your doctor before using Insulin Isophane/NPH. It should be used only when needed and when the potential benefits outweigh the potential risks.

Caution in Other Conditions

  • Patients with renal (kidney) or hepatic (liver) impairment should use Insulin Isophane/NPH with caution as these conditions can affect insulin metabolism.

  • Individuals with heart disease should also exercise caution as Insulin Isophane/NPH might cause fluid retention and lead to heart failure in some cases.

Special Dietary and Lifestyle Recommendations

  • Regular physical activity can help maintain healthy blood sugar levels but make sure to monitor your glucose levels before and after exercise.

  • Regular self-monitoring of blood glucose is recommended.

Frequently asked questions

No, Insulin Isophane/NPH is not a steroid. It is a type of human insulin used to manage blood sugar levels in people with diabetes.

Insulin Isophane/NPH is not addictive and does not lead to dependency. However, it is essential for managing blood sugar levels in people with diabetes, who may need to take it for an extended period.

Insulin Isophane/NPH has no known effects on the menstrual cycle. If you notice any changes in your menstrual cycle while using this medication, please consult your doctor.

While certain lifestyle changes and natural remedies might help in managing blood sugar levels, they are not substitutes for insulin therapy in people with diabetes. Always consult your doctor before trying any natural alternatives.

One possible side effect of Insulin Isophane/NPH use can be weight gain. If you experience significant weight changes while on this medication, consult your doctor for advice.

If you develop symptoms of an allergic reaction, such as rash, itching or swelling, severe dizziness, or trouble breathing after using Insulin Isophane/NPH, seek immediate medical attention.

While Insulin Isophane/NPH does not typically affect sleep directly, poorly managed blood sugar levels might indirectly affect your sleep pattern. If you notice unusual changes in your sleeping habits after starting this medication, consult your doctor for advice.

Terms & Conditions


Insulin Isophane/nph in other salts

Available medicines for INSULIN ISOPHANE/NPH
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Insugen N 100iu Injection 10ml
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Humanext N 40 IU Injection 10 ML
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