Human Immunoglobulin

Expert Advice

Dosage Forms Available

• Human Immunoglobulin is available as a liquid solution and as a lyophilized powder.

• It can be administered intravenously (IVIG) directly into a vein. It can also be given under the skin, known as Subcutaneous Immunoglobulin (SCIG). Less commonly, it may be injected into a muscle, termed Intramuscular Immunoglobulin (IMIG).

Age and Dose Restrictions

• Human Immunoglobulin is meant for both adult and paediatric patients.

• The age range and exact dose are determined by the specific condition being managed, and this should always be under the supervision of a doctor.

Contraindications

• Patients who have had an anaphylactic or severe systemic reaction to Human Immunoglobulin in the past should not take this medicine.

• It is also contraindicated in patients with selective IgA deficiency with known anti-IgA antibodies due to the risk of severe hypersensitivity reactions.

Other Medications to Avoid

• Human Immunoglobulin may interact with live attenuated virus vaccines (such as MMR and varicella). The vaccines should ideally be given at least 4 weeks before or 4 to 11 months after administration of Human Immunoglobulin.

Overdose and Missed Dose

• An overdose of Human Immunoglobulin can cause severe adverse reactions such as an increase in heart rate, blood pressure, and fever. If you suspect an overdose, seek medical attention immediately.

• If you forget a dose, administer it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose. Do not double-dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• If you experience a headache or fatigue after administration, rest and hydrate yourself.

• For nausea, try taking the medicine with or after meals.

• For fever or chills, keep yourself cool and well-hydrated.

Use in Driving and Operating Machinery

• Human Immunoglobulin may cause dizziness or tiredness. If you experience these side effects, avoid driving or operating heavy machinery until you feel capable.

Use in Pregnancy and Lactation

• The use of Human Immunoglobulin during pregnancy is a Category C, which means it should be used only if clearly needed.

• It is not known whether Human Immunoglobulin is excreted in breast milk. Therefore, caution is advised when administering it to a nursing woman.

Caution in Other Conditions

• Patients with renal insufficiency should exercise caution when taking Human Immunoglobulin due to the risk of acute kidney injury.

• Diabetic patients should also be careful as some products contain sugars like glucose and maltose.

• Patients with a history of cardiovascular or thromboembolic disease, as well as those with advanced age, should also exercise caution.

Special Dietary and Lifestyle Recommendations

• Maintain a balanced diet rich in fruits, vegetables and lean protein to support your immune system.

• Regular hydration is important for general health and can help manage some side effects like fatigue and headache.

• Adequate rest is beneficial for the body's recovery process and for the management of fatigue associated with treatment.

• Regular, light physical activity can help manage fatigue and maintain overall health.

Frequently asked questions

Terms & Conditions