Furazolidone + Metronidazole
Uses of Furazolidone + Metronidazole
Furazolidone + Metronidazole is primarily used to manage diarrhoea, dysentery, stomach and intestinal infections coupled with food poisoning. It belongs to the class of antibiotics known as nitrofuran antibacterial agent and nitroimidazole's.
Side effects of Furazolidone + Metronidazole
Nausea
Vomiting
Stomach upset
Diarrhoea or constipation
Headache
Dizziness
Dry mouth
Unpleasant metallic taste
How Furazolidone + Metronidazole works
Furazolidone is a nitrofuran antibacterial agent and monoamine oxidase inhibitor It works by interfering with the enzymes and proteins that bacteria need to survive in the human body. By doing this, it disrupts the formation of the bacterial cell wall, which leads to the bacterial cells breaking down and dying.
Metronidazole is another type of antibiotic known as nitroimidazole. It acts on the DNA of bacteria and parasites. This damages their DNA and kills these microorganisms.
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Expert Advice
Dosage Forms Available
The combination of Furazolidone + Metronidazole is available for oral administration (tablets and suspensions).
Age and Dose Restrictions
This medicine is intended for use by adults and children.
Contraindications
Furazolidone + Metronidazole is contraindicated in patients with known allergies to either of these medicines. Patients with Cockayne syndrome, a rare genetic disorder, should not take this combination. It is also contraindicated in anyone who has consumed alcohol in the past three days or taken disulfiram in the past two weeks.
Other Medications to Avoid
This combination may interact with disulfiram (such as chloramphenicol), anticoagulants (like warfarin), certain HIV medications (such as protease inhibitors like ritonavir, lopinavir, and atazanavir), antimanic agents (like lithium), H2 antagonists (like cimetidine), barbiturates (such as phenobarbital), and anticonvulsants (like phenytoin).
Overdose and Missed Dose
An overdose of Furazolidone + Metronidazole may lead to severe nausea, vomiting, dizziness, and neurological symptoms. If an overdose is suspected, seek emergency medical attention immediately.
If a dose is missed, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.
Taking this medication with food can help minimise gastrointestinal side effects like nausea and vomiting.
Staying well-hydrated can help manage side effects like dry mouth.
Use in Driving and Operating Machinery
Furazolidone + Metronidazole may cause dizziness. If you feel dizzy or lightheaded after taking this medication, avoid driving or operating heavy machinery until you know how it affects you.
Use in Pregnancy and Lactation
Furazolidone + Metronidazole should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing mothers should discard breast milk during treatment and for 24-48 hours after the last dose to avoid exposing infants to the medication.
Caution in Other Conditions
Patients with liver disease, kidney disease, blood disorders, or neurological conditions should exercise caution when taking Furazolidone + Metronidazole.
Special Dietary and Lifestyle Recommendations
Stay well-hydrated and maintain a balanced diet to support overall health while taking this medicine.
Regularly monitor your health while taking this medication, particularly if you have a pre-existing liver or kidney condition.
Frequently asked questions
Does Furazolidone + Metronidazole have any effect on sleep?
Some people may experience dizziness as a side effect which could potentially impact sleep. If you experience persistent sleep issues while taking this medicine, consult your doctor.
Will Furazolidone + Metronidazole affect fertility?
If you are planning to conceive or are facing fertility issues, it is advisable to discuss this with your doctor.
Is it safe to take Furazolidone + Metronidazole daily?
Yes, it is safe to take Furazolidone + Metronidazole daily as directed by your doctor. Do not self-medicate or alter the dosage without consulting your doctor.
What is the best time to take Furazolidone + Metronidazole?
The best time to take Furazolidone + Metronidazole is as directed by your doctor. The medication should be taken with food to minimise gastrointestinal side effects.
Is Furazolidone + Metronidazole available over the counter, or do I need a prescription?
Furazolidone + Metronidazole is a prescription medicine. You should only use it under the guidance of a doctor who will determine the appropriate dosage and duration for your condition.
What is the duration of treatment with Furazolidone + Metronidazole?
The duration of treatment with Furazolidone + Metronidazole depends on the specific infection being managed and individual patient factors. Your doctor will provide a recommended course length based on these considerations.
How much time does Furazolidone + Metronidazole take to show its effect?
The time taken by Furazolidone + Metronidazole to show its effect may vary depending on the individual and the type and severity of infection being managed.
Furazolidone + Metronidazole in other salts
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