Folic Acid + Methylcobalamin + Niacinamide
Uses of Folic Acid + Methylcobalamin + Niacinamide
The primary use of Folic Acid + Methylcobalamin + Niacinamide is to manage and prevent deficiencies of these essential B vitamins. The combination belongs to the class of vitamin supplements.
Secondary uses include support in healthy cell growth and function, neural tube defect prevention during pregnancy, and aiding in the proper functioning of the brain and nervous system.
Side effects of Folic Acid + Methylcobalamin + Niacinamide
Stomach upset
Diarrhoea
Rash
Sleep disorders
Mild burning or itching (topical niacinamide)
How Folic Acid + Methylcobalamin + Niacinamide works
Folic Acid + Methylcobalamin + Niacinamide is a combination of vitamins.
Folic Acid is a form of Vitamin B9. It is converted in the body to tetrahydrofolate, which acts as a coenzyme in DNA, RNA, and amino acid synthesis. This helps in cell division and replication, supporting healthy cell growth and function.
Methylcobalamin is an active form of Vitamin B12. It functions as a coenzyme for key metabolic processes like DNA synthesis, red blood cell formation, and nervous system maintenance. It also helps metabolise homocysteine, an amino acid that can be harmful at high levels.
Niacinamide or Vitamin B3, is required for the proper function of fats and sugars in the body and to maintain healthy cells. It is converted into nicotinamide adenine dinucleotide (NAD) in the body. NAD is crucial for cellular metabolism, DNA repair, and cell signalling.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
The Folic Acid + Methylcobalamin + Niacinamide combination is available in tablet, capsule, and liquid formulations that are taken orally.
Age and Dose Restrictions
This combination is usually recommended for adults and children above the age of 12 years.
Contraindications
This combination is contraindicated in individuals who have known allergies to either folic acid, methylcobalamin, or niacinamide. Additionally, people with vitamin B12 deficiency should exercise caution when taking folic acid as it can mask B12 deficiency symptoms.
Other Medications to Avoid
This combination may interact with certain medications including antiepileptics (such as phenobarbital and phenytoin), anticancer medicines (like methotrexate), antimalarials (such as pyrimethamine) and certain antibiotics (including dapsone).
Overdose and Missed Dose
Overdosing on Folic Acid + Methylcobalamin + Niacinamide may lead to symptoms such as abdominal cramps, diarrhoea, rash, sleep disorders, irritability, confusion, nausea, stomach upset, behaviour changes, skin reactions, seizures, gas and excitability. If you suspect an overdose, immediately seek medical attention.
If a dose is missed, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the one that was missed.
Management of Side Effects
Most side effects are temporary and will subside once you stop taking this medicine. However, here are some tips to manage common side effects:
If you experience stomach discomfort, try taking the medication with meals.
If you feel dizzy, ensure to get up slowly from a sitting or lying position.
Use in Driving and Operating Machinery
This combination may cause dizziness or sleepiness in some individuals. It is advised to refrain from driving or operating heavy machinery until you know how this medicine affects you.
Use in Pregnancy and Lactation
It is essential to consult your doctor before using this combination if you are pregnant or breastfeeding. Your doctor will evaluate the benefits and risks before prescribing this medication.
Caution in Other Conditions
Individuals with kidney disease, liver disease, and malabsorption syndromes should use this combination with caution. Regular monitoring of vitamin B12 levels is recommended for those on long-term treatment with this combination.
Special Dietary and Lifestyle Recommendations
Maintain a balanced diet rich in leafy greens, lean proteins, and whole grains. These foods are rich in B vitamins and can supplement the effects of the medication.
Regular moderate physical activity can help maintain overall health and wellness.
Frequently asked questions
Is Folic Acid + Methylcobalamin + Niacinamide a vegetarian source of vitamins?
Yes, Folic Acid + Methylcobalamin + Niacinamide is a combination of essential B vitamins derived synthetically and not from animal sources, hence is suitable for vegetarians.
Will Folic Acid + Methylcobalamin + Niacinamide help improve my mood?
The combination of these essential B vitamins aids in the proper functioning of the brain and nervous system, potentially impacting mood positively. However, it is important to consult your doctor about this.
Is Folic Acid + Methylcobalamin + Niacinamide addictive?
No, Folic Acid + Methylcobalamin + Niacinamide is not known to cause addiction or dependency as they are essential B vitamins.
Is it normal for urine to turn yellow after taking Folic Acid + Methylcobalamin + Niacinamide?
Some B vitamins like riboflavin (not present in this particular combination) can turn urine a bright yellow colour. However, Niacinamide (Vitamin B3) can still cause mild changes in urine colour, though it typically doesn't produce the bright yellow effect associated with Riboflavin. If you're noticing a change in urine colour, it's likely due to how your body metabolizes and excretes these vitamins, and it's generally harmless. If you're concerned, consulting your doctor is a good idea.
Is Folic Acid + Methylcobalamin + Niacinamide a steroid?
No, Folic Acid + Methylcobalamin + Niacinamide is not a steroid. It is a combination of essential B vitamins needed for various physiological functions.
What is the best time to take Folic Acid + Methylcobalamin + Niacinamide?
The best time to take these supplements would be as advised by your doctor. Some people may find them easier to digest when taken with meals.
How much time does Folic Acid + Methylcobalamin + Niacinamide take to work?
The time taken for these nutrients to work varies between individuals and depends on factors such as the body's absorption and metabolism rate.
Folic Acid + Methylcobalamin + Niacinamide in other salts
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