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Fluphenazine

Uses of Fluphenazine

  • The primary use of Fluphenazine is for managing schizophrenia and other psychotic disorders and belongs to antipsychotic medications.

  • It is also used for the management of manic episodes in bipolar disorder, severe anxiety, and severe nausea and vomiting.

Side effects of Fluphenazine

  • Drowsiness

  • Dizziness

  • Dry mouth

  • Constipation

  • Nausea and vomiting

How Fluphenazine works

  • Fluphenazine is an antipsychotic medication belonging to the phenothiazine class. It works by inhibiting the action of dopamine, a chemical that transmits messages in the brain. Dopamine is involved in regulating mood, thinking, and behaviour. By blocking dopamine receptors known as D2 receptors, Fluphenazine helps to adjust the balance of this substance in the brain.

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Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Fluphenazine can be taken orally (tablet, liquid (elixir and concentrate)), and intramuscular (infusion) routes.

Age and Dose Restrictions

  • This medicine is meant for adults.

Contraindications

  • Fluphenazine is contraindicated in patients with known hypersensitivity to Fluphenazine or other phenothiazines.

  • It is also contraindicated in patients with comatose states, severe central nervous system depression, blood dyscrasias or bone marrow suppression.

Other Medications to Avoid

  • Fluphenazine may interact with other antipsychotics and neuroleptics (eg., haloperidol, pimozide), antidepressants (eg., amitriptyline, imipramine ) SSRIs (eg., fluoxetine, escitalopram), anticonvulsants and barbiturates (eg., carbamazepine, phenobarbital)and anticholinergic agents (eg., atropine, benztropine).

Overdose and Missed Dose

  • An overdose of Fluphenazine may cause severe drowsiness, loss of consciousness, high body temperature, irregular heartbeat or seizures. If you suspect an overdose, contact your doctor immediately.

  • If you miss a dose of Fluphenazine, take it as soon as you remember. But if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water could help to manage the side effects of dry mouth.

  • Standing up slowly from a seated or lying position can help manage dizziness and lightheadedness.

Use in Driving and Operating Machinery

  • This medicine can affect your ability to drive or operate heavy machines. Avoid these activities if you experience drowsiness, sedation or impaired concentration after taking this medicine.

Use in Pregnancy and Lactation

  • Fluphenazine should only be used during pregnancy if the potential benefits outweigh the risks. It is not recommended for use during breastfeeding as it can pass into breast milk and may affect the nursing infant. Always consult your doctor before using this medicine during pregnancy or lactation.

Caution in Other Conditions

  • Patients with a history of seizures or epilepsy, cardiovascular diseases, liver or kidney impairment, glaucoma, urinary retention or Parkinson's disease should exercise caution when taking Fluphenazine.

  • Elderly patients with dementia are also advised to exercise caution due to an increased risk of mortality.

Special Dietary and Lifestyle Recommendations

  • A balanced diet, including plenty of fruits and vegetables, lean proteins, whole grains, and healthy fats can support overall health and well-being.

  • Adequate sleep is essential for physical health and mental well-being. Trying to maintain a regular sleep schedule can be beneficial.

Frequently asked questions

No, Fluphenazine is not a steroid. It is an antipsychotic medicine belonging to the phenothiazine class.

Yes, one of the common side effects of Fluphenazine can be drowsiness and insomnia. Therefore, it might affect sleep patterns in some individuals.

Fluphenazine may affect fertility in some individuals. As an antipsychotic medication, it can cause hormonal changes, such as increased prolactin levels, which might impact menstrual cycles and fertility. If you have concerns about fertility while taking fluphenazine, consult your doctor.

Yes, it is safe to take Fluphenazine daily as prescribed by your doctor. The medication should be taken according to your doctor's instructions for the best results.

The onset of action for Fluphenazine depends on the route of administration. Oral and short-acting injectable forms may begin working within a few days, while long-acting forms may take several weeks.

The best time to take Fluphenazine is as directed by your doctor, which would typically be based on the specific indication for which it has been prescribed.

No, it's not advisable to stop taking Fluphenazine abruptly without consulting your doctor as it may lead to withdrawal symptoms or a relapse of the condition being managed. Always follow your doctor's instructions about how to safely stop taking this medicine.

Terms & Conditions

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