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Fentanyl

Uses of Fentanyl

  • Fentanyl, a strong opioid analgesic, is primarily used for managing severe chronic pain, especially in patients with advanced cancer.
  • It is also used for post-operative pain relief and as part of anesthesia during surgical procedures, often in combination with other anesthetic agents to enhance their effectiveness.

Side effects of Fentanyl

  • Nausea

  • Vomiting

  • Drowsiness

  • Dizziness

  • Constipation

How Fentanyl works

  • Fentanyl belongs to the category of synthetic opioid analgesics.

  • Acting as an opioid agonist, Fentanyl binds primarily to the mu-opioid receptors present in the brain and spinal cord. This binding process activates these receptors, thereby reducing the perception of pain, modifying the emotional response to pain, and inducing a state of relaxation as well as euphoria.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Fentanyl is available in a variety of forms. It can be administered as a transdermal patch that is applied onto the skin and provides a controlled release of the medicine over 72 hours.

  • Some buccal tablets and lozenges are meant to be absorbed through the lining of the mouth and sublingual tablets and sprays are absorbed under the tongue.

  • Fentanyl can also be given in the form of nasal sprays that are absorbed through the nasal mucosa.

  • Injectable solutions of Fentanyl can be administered either intravenously or intramuscularly.

Age and Dose Restrictions

  • Fentanyl is intended for use by adults and children who are at least 18 years old.

Contraindications

  • Fentanyl should not be used by patients who have a known hypersensitivity to it.

  • It is also contraindicated in patients with severe, untreated bronchial asthma or paralytic ileus, a condition where there is a blockage in the intestines.

Other Medications to Avoid

  • Fentanyl can interact with other central nervous system depressants (such as benzodiazepines and sedatives), antifungals (like ketoconazole), antibiotics (like rifampin) and serotonergic medicines (like fluoxetine).

Overdose and Missed Dose

  • Overdosing on Fentanyl can lead to severe respiratory depression, which can ultimately result in hypoxia, coma, and death. Immediate medical assistance is required in case of an overdose.

  • If you forget to administer a dose of Fentanyl, you should give the dose as soon as you remember.

Management of Side Effects

Most side effects of Fentanyl are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For nausea, it may help to rest and lie down.

  • For dizziness or lightheadedness, avoid sudden changes in posture and rise slowly from a sitting or lying position.

Use in Driving and Operating Machinery

  • Fentanyl may impair your ability to drive or operate heavy machinery. You should avoid these activities if you feel drowsy or dizzy after using this medicine.

Use in Pregnancy and Lactation

  • The use of Fentanyl during pregnancy or while breastfeeding should be done only under the guidance of a doctor.

Caution in Other Conditions

  • Patients with impaired pulmonary function, head injuries, brain tumours, increased intracranial pressure, or those with liver or kidney impairment should exercise caution while using Fentanyl.

Special Dietary and Lifestyle Recommendations

  • A balanced diet with an adequate intake of vitamins can support overall well-being.

  • Adequate hydration is essential for overall health.

  • Regular relaxation techniques such as deep breathing or yoga can help manage stress levels.

  • A good sleep pattern can help in managing chronic pain conditions.

Frequently asked questions

No, Fentanyl is not a steroid. It is a potent synthetic opioid analgesic.

Yes, Fentanyl can cause drowsiness and sedation, which could potentially affect sleep.

Fentanyl is not directly associated with affecting fertility. However, if you have concerns about fertility and are using Fentanyl, it is best to consult your doctor.

Fentanyl may be taken daily if prescribed by your doctor. However, due to its potential for dependence and addiction, it should be used exactly as directed.

The onset of action of Fentanyl varies with the formulation used injectable solutions act quickly (within minutes), while transdermal patches release the medicine slowly over time (up to 72 hours).

The timing of Fentanyl administration would depend on the specific formulation and the schedule advised by your doctor.

Yes, Fentanyl has a high potential for abuse and addiction due to its potent euphoric effects. Regular use can lead to physical dependence and tolerance.

Terms & Conditions

Available medicines for FENTANYL
Fent 50 MCG Injection 10 ML
Fent 50 MCG Injection 10 ML
Neon Laboratories Ltd
Pack of 10 ML
â‚ą88.56
MRP â‚ą108.00
18.00% OFF
Trofentyl Injection 10 ML
Trofentyl Injection 10 ML
Troikaa Pharmaceuticals Ltd
Pack of 10 ML
â‚ą109.06
MRP â‚ą133.00
18.00% OFF
Fendrop 50 MCG Injection 2 ML
Fendrop 50 MCG Injection 2 ML
Sun Pharma Laboratories Ltd.
Pack of 2 ML
â‚ą36.95
MRP â‚ą45.06
18.00% OFF
Trofentyl 50 MCG Injection 2 ML
Trofentyl 50 MCG Injection 2 ML
Troikaa Pharmaceuticals Ltd
Pack of 2 ML
â‚ą37.28
MRP â‚ą45.46
18.00% OFF
Durogesic 25 MCG Patch 3
Durogesic 25 MCG Patch 3
Janssen
Pack of 3 Units
â‚ą1217.70
MRP â‚ą1485.00
18.00% OFF
Durogesic 50 MCG Patch 3
Durogesic 50 MCG Patch 3
Janssen
Pack of 3 Units
â‚ą2344.38
MRP â‚ą2859.00
18.00% OFF
Fent 50 MCG Injection 2 ML
Fent 50 MCG Injection 2 ML
Neon Laboratories Ltd
Pack of 2 ML
â‚ą41.00
MRP â‚ą50.00
18.00% OFF
Fendrop 25 MCG Patch 1
Fendrop 25 MCG Patch 1
Sun Pharma Laboratories Ltd.
Pack of 1 Units
â‚ą248.25
MRP â‚ą302.75
18.00% OFF

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