Eszopiclone
Uses of Eszopiclone
Eszopiclone is primarily used in the management of insomnia, a sleep disorder characterized by difficulties in falling asleep or maintaining sleep. It belongs to the group of non-benzodiazepine hypnotic agents.
Side effects of Eszopiclone
Unpleasant taste
Headache
Drowsiness
Dizziness
Dry mouth
How Eszopiclone works
Eszopiclone is a non-benzodiazepine hypnotic agent.
It works by interacting with certain chemical receptors in the brain known as GABA-receptor complexes. By enhancing the activity of a neurotransmitter called GABA, it slows down the central nervous system. This produces a calming effect that induces sleep, helping to manage insomnia. The exact way in which Eszopiclone works to manage insomnia is not fully understood.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Eszopiclone is available in the form of oral tablets.
Age and Dose Restrictions
This medicine is meant for adults only. It is not recommended for use by children and adolescents under the age of 18 years.
Contraindications
Eszopiclone is contraindicated in patients with a known hypersensitivity to Eszopiclone or any of the inactive ingredients in the formulation.
It is also contraindicated in patients with severe hepatic impairment due to the potential for increased medicine exposure.
Other Medications to Avoid
Eszopiclone may interact with CNS depressants (such as benzodiazepines, opioids, and tricyclic antidepressants) and strong CYP3A4 inhibitors (such as ketoconazole and ritonavir).
Overdose and Missed Dose
An overdose of Eszopiclone can lead to serious complications ranging from somnolence to coma, respiratory depression, and even death. If you suspect that you have taken an excessive dose of this medicine, seek immediate medical attention.
If you miss a dose of Eszopiclone, take it as soon as you remember, provided you have at least 7 to 8 hours to dedicate to sleep. If it is close to your next dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to compensate for a missed one.
Management of Side Effects
Most side effects of Eszopiclone are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drink plenty of water to manage dry mouth.
Rest and avoid quick movements if you experience dizziness.
Suck on sugar-free candy or chew sugar-free gum to manage dry mouth.
Use in Driving and Operating Machinery
Eszopiclone may impair your ability to drive or operate machinery due to its sedative effects. Avoid undertaking these activities if you feel drowsy or less alert after taking this medicine.
Use in Pregnancy and Lactation
The use of Eszopiclone during pregnancy and lactation should only be considered if the potential benefit justifies the potential risk to the fetus or nursing infant. Always consult your doctor for advice on this matter.
Caution in Other Conditions
Patients with respiratory diseases such as COPD or obstructive sleep apnea should exercise caution when taking Eszopiclone due to its potential to depress respiratory function.
Elderly patients should be started on a low dose of Eszopiclone and monitored closely due to their increased risk of cognitive and motor impairment.
Special Dietary and Lifestyle Recommendations
Maintain a regular sleep schedule even on weekends.
Create a peaceful sleep environment with comfortable bedding, temperature control, and minimal noise and light.
Frequently asked questions
Are there vegetarian or vegan versions of Eszopiclone available?
The composition of Eszopiclone tablets would vary by manufacturer. If you require a vegetarian or vegan version, you should consult your pharmacist or doctor for suitable options.
Is there a potential for Eszopiclone to be habit-forming?
Yes, Eszopiclone does have the potential to cause tolerance, physical dependence, and abuse, especially if used over an extended period.
Can Eszopiclone cause any abnormal thoughts or behaviours?
Rarely, some people may experience abnormal thoughts and behaviours such as aggressiveness, confusion or hallucinations after taking Eszopiclone.
How quickly does Eszopiclone start working?
Eszopiclone is known to work quite quickly. Most patients tend to fall asleep within approximately 30 minutes of taking the medicine.
Are there any natural alternatives to Eszopiclone for managing insomnia?
While there may be various natural methods to help manage insomnia, such as maintaining a regular sleep schedule or practising relaxation techniques, these should not be considered replacements for prescribed medication like Eszopiclone. Always consult your doctor before discontinuing any prescribed treatment.
Can Eszopiclone help improve my sleep quality?
Yes, Eszopiclone is designed to help you fall asleep faster and stay asleep longer during the night. It also helps reduce the number of times you wake up in the night, thus improving your overall sleep quality.
Is Eszopiclone an over-the-counter medicine?
No, usually Eszopiclone is not available over the counter and requires a prescription from a doctor.
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