Entecavir
Uses of Entecavir
Entecavir is primarily used for managing chronic hepatitis B virus (HBV) infection in adults, and it belongs to the class of antiviral medications known as nucleoside reverse transcriptase inhibitors (NRTIs).
Side effects of Entecavir
Headaches
Fatigue
Dizziness
Nausea
Insomnia
How Entecavir works
Entecavir is a type of antiviral medicine known as a nucleoside reverse transcriptase inhibitor (NRTI).
Its main action is to block the activity of an enzyme in the hepatitis B virus called reverse transcriptase. This enzyme plays a crucial role in the reproduction of the virus. By stopping this enzyme from working, Entecavir halts the multiplication of the virus, reducing its amount in the body. This helps to minimise further damage to the liver caused by the virus. However, it is important to note that while Entecavir manages and controls hepatitis B virus, it does not completely eliminate it from the body.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Entecavir can be taken orally (tablet and oral solution).
Age and Dose Restrictions
Entecavir is meant for adults, specifically those with chronic Hepatitis B virus (HBV) infection.
Contraindications
Entecavir is contraindicated in patients with known hypersensitivity to it or to any inactive ingredients found in the tablets or oral solution.
Other Medications to Avoid
Entecavir can interact with other HBV antivirals (such as lamivudine, adefovir, and telbivudine).
Overdose and Missed Dose
If an overdose occurs, contact your doctor immediately. The symptoms of overdose are not well known but can possibly cause severe side effects.
If you miss a dose of Entecavir, take it as soon as you remember unless it is nearly time for your next dose. In that case, just skip the missed dose and continue with your regular dosage schedule.
Management of Side Effects
Most side effects of Entecavir are temporary and generally harmless and resolve when you stop taking the medicine. However, if you experience severe side effects or worsening symptoms, consult your doctor. To manage side effects:
Drinking plenty of fluids can aid in managing symptoms such as headaches and fatigue.
Try taking the medication with food if nausea is being experienced.
Resting adequately can help manage fatigue and dizziness.
Use in Driving and Operating Machinery
Entecavir can cause dizziness and therefore your ability to drive or operate heavy machinery could be affected. Avoid these activities until you know how you are affected by the medication.
Use in Pregnancy and Lactation
If you are pregnant or breastfeeding, consult your doctor before using this medicine.
Caution in Other Conditions
Entecavir should be used with caution in patients with HIV infection, kidney disease, and those who have previously been treated with HBV antivirals.
Special Dietary and Lifestyle Recommendations
Practise safe sex and use clean needles if you use medicines to help prevent the spread of HBV.
Frequently asked questions
Does Entecavir cause sleep disturbances?
No, Entecavir is not typically associated with causing sleep disturbances. However, individual reactions to any medication can vary. If you experience unexpected sleep problems while taking Entecavir, consult your doctor.
Does Entecavir affect fertility?
There is no evidence to suggest that Entecavir affects fertility in either men or women. However, if you are planning to become pregnant and are taking Entecavir, it is advisable to discuss this with your doctor.
Can I take Entecavir every day?
Yes, Entecavir is usually prescribed to be taken as advised by your doctor. The duration and dosage depend upon your medical condition and response to treatment.
How does Entecavir work in my body?
Entecavir prevents the hepatitis B virus from multiplying in the body. It achieves this by inhibiting a key enzyme called viral DNA polymerase, which is vital for the virus's replication process.
When is the best time to take Entecavir?
The best time to take Entecavir is as recommended by your doctor. It is generally advised to take this medicine at the same time each day for maximum effectiveness.
Can I buy Entecavir over the counter?
No, Entecavir is not available over the counter. This medication requires a prescription from a doctor.
Can I take Entecavir if I am vegan?
Yes, you can take Entecavir if you are vegan. There are no animal-derived ingredients in this medication.
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