Empagliflozin + Metformin
Uses of Empagliflozin + Metformin
Empagliflozin + Metformin is primarily used to manage blood sugar levels in adults with type 2 diabetes. It belongs to the group of oral antidiabetic medicines.
In combination with healthy lifestyle changes, such as a balanced diet and regular exercise, it can help manage blood sugar levels more effectively.
This may also help prevent complications of diabetes, such as kidney damage, nerve problems, and heart disease.
Side effects of Empagliflozin + Metformin
Urinary tract infections
Genital fungal infections
Diarrhoea and nausea
Abdominal pain
Increased frequency of urination
How Empagliflozin + Metformin works
Empagliflozin + Metformin is a combination medicine for managing blood sugar levels in type 2 diabetes.
Empagliflozin is an SGLT2 inhibitor. It works by increasing the excretion of glucose in the urine. This happens when Empagliflozin blocks the reabsorption of glucose in the kidneys, thereby removing excess sugar from the body.
Metformin is a biguanide. It reduces the amount of sugar produced by the liver, decreases the absorption of sugar from the gut, and enhances the body's sensitivity to insulin. This improves the body's ability to use glucose effectively.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Empagliflozin + Metformin is available in the form of film-coated tablets for oral administration.
Age and Dose Restrictions
Empagliflozin + Metformin is intended for use by adults only. It may not be suitable for individuals under 18 years of age.
Contraindications
Empagliflozin + Metformin is contraindicated in patients with severe kidney disorders, end-stage renal disease, or those undergoing dialysis.
It should not be used by individuals with acute or chronic metabolic acidosis, including diabetic ketoacidosis.
Other Medications to Avoid
Empagliflozin + Metformin may interact with diuretics (such as furosemide and hydrochlorothiazide), insulin or sulfonylureas (like glipizide), and medicines that affect kidney function (including cimetidine and vandetanib). Medicines that affect blood sugar control (such as corticosteroids and phenytoin) can also interact with this combination medicine.
It is crucial to consult your doctor before starting any new prescription or over-the-counter medications while taking Empagliflozin + Metformin.
Overdose and Missed Dose
An overdose of Empagliflozin + Metformin could result in severe symptoms such as lactic acidosis or low blood sugar. If you suspect you have overdosed, seek medical attention immediately.
If you miss a dose of Empagliflozin + Metformin, take it as soon as you remember. However, skip the missed dose if it is almost time for your next scheduled dose. Do not double up on doses to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless, resolving themselves when the medication is discontinued. However, if you experience any severe side effects or worsening of symptoms, please consult your doctor.
Drinking plenty of fluids can help manage increased urination and reduce the risk of dehydration.
Eating small, frequent meals can help manage gastrointestinal symptoms such as nausea, indigestion, and abdominal pain.
Use in Driving and Operating Machinery
Empagliflozin + Metformin may cause dizziness or fatigue in some individuals. If you experience these side effects, avoid driving or operating heavy machinery.
Use in Pregnancy and Lactation
The use of Empagliflozin + Metformin during pregnancy or while breastfeeding should be decided in consultation with your doctor.
Caution in Other Conditions
Caution is advised when using Empagliflozin + Metformin in patients with liver problems or a history of urinary tract infections or genital yeast infections.
Individuals at risk for dehydration or low blood volume should also exercise caution when taking this medication.
Special Dietary and Lifestyle Recommendations
Maintain a balanced diet that is low in sugars and carbohydrates to help keep blood sugar levels stable.
Regular physical activity can also aid in managing blood sugar levels and maintaining overall health.
Avoid consuming excessive amounts of alcohol while taking Empagliflozin + Metformin, as it could increase the risk of lactic acidosis.
Frequently asked questions
Can Empagliflozin + Metformin be used to manage type 1 diabetes?
No, Empagliflozin + Metformin is not suitable for managing type 1 diabetes. It is primarily used to manage type 2 diabetes in adults.
Is there a risk of hypoglycemia with Empagliflozin + Metformin?
There is a minimal risk of hypoglycaemia (low blood sugar levels) when using this combination alone. However, the risk increases if it's used alongside other glucose-lowering medicines, such as insulin or sulfonylureas.
Can I consume alcohol while on Empagliflozin + Metformin?
It is generally advised to limit or avoid alcohol consumption while taking this medicine because alcohol can increase the risk of lactic acidosis, a serious side effect of metformin.
Do I need to monitor my blood sugar levels while taking Empagliflozin + Metformin?
Yes, regular monitoring of blood sugar levels is necessary as it helps track the effectiveness of the treatment and aids in the detection of any potential complications at an early stage.
Is Empagliflozin + Metformin safe for long term use?
Empagliflozin + Metformin can be used for a longer time as your doctor has advised to manage diabetes.
Is Empagliflozin + Metformin safe for people with kidney disease?
This medication should be used with caution in patients with kidney disease. The dosage may need to be adjusted based on kidney function, and monitoring of kidney function is required.
Can Empagliflozin + Metformin cause urinary tract infections (UTIs)?
Yes, one of the common side effects of this medication is urinary tract infections. This is due to the mechanism of action of empagliflozin, which increases glucose excretion in urine. If you experience symptoms like a burning sensation or pain during urination, increased frequency of urination, or lower abdominal pain, please get in touch with your doctor.
Empagliflozin + Metformin in other salts
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