Drotaverine
ANTISPASMODICUses of Drotaverine
- Drotaverine is an antispasmodic drug used to relieve pain associated with smooth muscle spasms, such as those caused by intestinal, bile, and kidney stones, uterine spasms, and irritable bowel syndrome.
- It is also effective for managing menstrual pain, abdominal pain, and gastrointestinal colicky pain.
Side effects of Drotaverine
- Nausea
- Constipation
- Indigestion
- Headache
- Dizziness
- Flushing
How Drotaverine works
- Drotaverine is an antispasmodic agent. It relaxes smooth muscles in blood vessels and the gastrointestinal tract. By inhibiting phosphodiesterase enzymes, it increases cyclic adenosine monophosphate (cAMP), leading to muscle relaxation. This activity makes it effective in relieving spasms, particularly in conditions involving smooth muscle hyperactivity, such as abdominal pain and menstrual cramps.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Drotaverine can be taken orally (tablet and suspension) and intravenously (injection).
Age and Dose Restrictions
- It can be used by adults and children above 1 year of age.
Contraindications
- This medicine is contraindicated in patients with a history of hypersensitivity to Drotaverine.
Medications to Avoid with This Drug
- Avoid taking muscarinic antagonists (atropine), antiparkinson agents (levodopa), and antidepressants such as diazepam. These medications may alter the safety and effectiveness of this medicine.
Overdose and Missed Dose
- Overdose can cause weakness, discomfort, dizziness, headache, a drop in blood pressure and sleepiness. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
- If you miss a dose of this medicine, take it as soon as you remember, but if the next dose is near, skip the missed dose and resume the regular dosing regime.
Management of Side Effects
- Take this medicine with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- This medicine can cause dizziness. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination after taking it.
Use in Pregnancy and Lactation
- Caution is advised during pregnancy. It is not recommended during breastfeeding.
Caution in Other Conditions
- Caution is advised in older adults and patients with heart conditions, hypotension, and kidney and liver impairment.
Special Dietary & Lifestyle Recommendation
- Avoid alcohol consumption, as it may increase the risk of gastrointestinal irritation and other adverse effects.
- Take Drotaverine only for the prescribed duration.
- Engage in regular, low-impact exercises such as walking, swimming, or cycling to improve flexibility and strengthen muscles.
- Consider incorporating probiotics into your diet to promote a healthy balance of gut bacteria and potentially reduce symptoms.
- Reduce consumption of caffeine, as these can exacerbate IBS symptoms.
Frequently asked questions
1. Is Drotaverine a painkiller?
No, this medicine is not specifically a painkiller. It is an antispasmodic medication primarily used to relieve smooth muscle spasms, particularly in the gastrointestinal tract and blood vessels.
2. How much time do Drotaverine take to work?
This medicine typically shows its effects within 30 minutes to an hour after ingestion. However, individual responses may vary.
3. Is Drotaverine a habit-forming medicine?
No, this medicine is not habit-forming and is generally safe when used as directed.
4. Is Drotaverine available over the counter, or do I need a prescription?
Yes, this medicine usually requires a prescription and is not available over the counter.
5. How long does the effect of Drotaverine last?
This medicine may provide relief for up to a few hours. However, the duration of effect of this medication can vary with the individual and the severity of the condition being treated.
6. Can Drotaverine be taken for stomach pain?
Yes, this medicine is effective in reducing stomach pain associated with irritable bowel syndrome. However, its use for stomach pain should only be done when a doctor advises.
7. Does Drotaverine cause sleepiness?
Yes, this medicine may cause sleepiness when the dosage is exceeded.
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