The primary use of Doxazosin is to manage high blood pressure and symptoms of an enlarged prostate gland, a condition known as benign prostatic hyperplasia (BPH). Doxazosin is part of the alpha-blockers class of medicines.
In addition, Doxazosin can also be used to manage other health conditions as determined by your doctor.
Dizziness or fainting
Headache
Fatigue or tiredness
Swelling in hands, feet, ankles, or lower legs
Shortness of breath
Doxazosin is an alpha-blocker.
It works by blocking the alpha-1 adrenergic receptors in the body. This action helps to relax and widen blood vessels, which reduces blood pressure in the prostate and bladder neck, Doxazosin's blocking of alpha-1 adrenergic receptors leads to the relaxation of muscles. This aids in improving urine flow and helps reduce symptoms associated with an enlarged prostate gland.
Doctor of Medicine
BMS, FMC, MD Resident
Doxazosin is available in the form of immediate-release tablets designed for oral administration.
It's also available as extended-release tablets for oral use.
This medication is intended for use by adults of age above 18 years.
Doxazosin is contraindicated in patients with known hypersensitivity to quinazolines (the class of medicines to which Doxazosin belongs).
It's also contraindicated in patients with a history of orthostatic hypotension (sudden fall in blood pressure when standing).
Doxazosin can interact with antihypertensive agents (such as diuretics and beta-blockers), phosphodiesterase 5 inhibitors (such as sildenafil and tadalafil), antifungals (like ketoconazole) and antivirals (ritonavir).
Overdose of Doxazosin may result in profound hypotension (very low blood pressure) which should be treated by placing the patient in a supine position (lying flat with face upward).
If a dose of Doxazosin is missed, it should be taken as soon as it is remembered. However, if it's nearly time for the next dose, skip the missed dose and continue with the regular schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of the symptoms, please consult your doctor.
Drinking plenty of water can help manage minor side effects such as dry mouth or constipation.
Standing up gradually can help manage dizziness or fainting, which may occur particularly when rising from a sitting or lying position.
Doxazosin may cause dizziness or fainting, especially when you first start taking the medicine. Therefore, caution is advised when driving or operating heavy machinery.
Use of Doxazosin during pregnancy and breastfeeding should only be considered if the potential benefit to the mother outweighs the possible risk to the fetus or child. Consult your doctor before using Doxazosin during these periods.
Patients with severe liver or kidney disease need to use Doxazosin with caution and under close medical supervision due to the increased risk of adverse effects.
Caution is also advised in patients with a history of gastrointestinal disorders such as oesophageal reflux or peptic ulcer disease.
Regular monitoring of blood pressure is recommended as Doxazosin is used in managing hypertension.
A diet low in salt and saturated fats, along with regular exercise, can help manage high blood pressure effectively.
Limiting caffeine and alcohol intake can also assist in managing the symptoms of benign prostatic hyperplasia (BPH), another condition that Doxazosin is used for.
Frequently asked questions
No, Doxazosin is not a steroid. It belongs to the class of medications known as alpha-blockers.
Yes, drowsiness can be a side effect of Doxazosin, which may affect sleep patterns. If you experience significant drowsiness or any other sleep disturbances while taking Doxazosin, it is important to consult your doctor for further guidance.
Doxazosin is not directly associated with affecting fertility. However, if you are planning for a baby and are taking this medication, it is advisable to discuss it with your doctor.
Doxazosin is not associated with affecting hormones. However, all medicines can have different effects on different individuals. If you notice any unusual changes while taking this medication, consult your doctor immediately.
The onset of action of Doxazosin may vary from person to person. While some people may see an effect within a few days of starting the medication, for others it may take several weeks to see the full benefits.
Doxazosin can be taken at any time of the day, with or without food based on your doctor's recommendations. However, the extended-release version should be taken with breakfast to ensure proper absorption.
Yes, weight gain is a possible side effect of Doxazosin. However, everyone does not experience this and if you notice an unusual weight gain while taking this medication, it is advised to consult your doctor.
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