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Diloxanide + Simethicone + Tinidazole

Uses of Diloxanide + Simethicone + Tinidazole

  • Diloxanide + Simethicone + Tinidazole is used to manage intestinal amoebiasis. This medicine belongs to the group of antibiotics and antiprotozoal medications.

  • Additionally, it is also used to provide relief from excess gas, bloating, and stomach cramps that are often associated with this condition.

Side effects of Diloxanide + Simethicone + Tinidazole

  • Nausea

  • Vomiting

  • Headache

  • Diarrhoea

  • Skin rash

How Diloxanide + Simethicone + Tinidazole works

  • Diloxanide + Simethicone + Tinidazole is an antiprotozoal and antibiotic combination.

  • Diloxanide is an antiprotozoal. It works against Entamoeba histolytica, a parasite that causes infections in the intestines.

  • Simethicone is an anti-foaming agent. It changes the surface tension of gas bubbles in the stomach and intestines, causing them to merge and disperse. This enables you to eliminate gas more easily, providing relief from bloating and discomfort.

  • Tinidazole is an antibiotic. It interferes with the DNA of bacteria and other microorganisms, preventing them from reproducing and growing. This helps manage various infections caused by bacteria and parasites.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Diloxanide + Simethicone + Tinidazole is available in oral form as tablets.

  • This allows for the convenient administration of the combination through the mouth, ensuring that the active ingredients are delivered directly to the gastrointestinal tract where they are needed.

Age and Dose Restrictions

  • This medicine is intended for use in adults and children over the age of three years.

Contraindications

  • This combination is contraindicated in patients with known hypersensitivity to any of the ingredients.

  • It is also contraindicated in patients with liver disease, neurological disorders, or blood dyscrasias.

Other Medications to Avoid

  • Diloxanide + Simethicone + Tinidazole can interact with blood-thinning medications (such as warfarin, heparin), antibiotics (such as ciprofloxacin, metronidazole), antifungal medicines (such as fluconazole, itraconazole), and alcohol. It may also interact with antacids (such as aluminium hydroxide, magnesium hydroxide) and seizure medications (such as phenytoin, carbamazepine).

Overdose and Missed Dose

  • An overdose of Diloxanide + Simethicone + Tinidazole may lead to symptoms such as nausea, vomiting, rapid heartbeat, and dizziness. If you suspect an overdose, it is crucial to seek medical attention promptly.

  • If you miss a dose of Diloxanide + Simethicone + Tinidazole, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea, try taking this medicine with food.

  • If you experience dizziness, ensure you sit or lie down until the feeling passes.

Use in Driving and Operating Machinery

  • Diloxanide + Simethicone + Tinidazole may cause dizziness or drowsiness. It is advisable to avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • Diloxanide + Simethicone + Tinidazole is not advised during pregnancy and while breastfeeding unless deemed necessary by a doctor.

  • Always consult your doctor before taking any medication during pregnancy or lactation.

Caution in Other Conditions

  • Caution is advised when administering Diloxanide + Simethicone + Tinidazole to patients with kidney disease or liver impairment.

  • Patients with a history of blood disorders should also use this medicine with care.

Special Dietary and Lifestyle Recommendations

  • Ensure adequate hydration to help manage diarrhoea if present.

  • Consider eating smaller, more frequent meals if bloating or gas is a problem.

  • Include probiotic-rich foods like yoghurt in your diet to help restore natural gut flora balance after completion of treatment with this medicine.

  • Avoid foods that can exacerbate bloating and gas, such as carbonated drinks certain legumes and cruciferous vegetables.

Frequently asked questions

No, Diloxanide + Simethicone + Tinidazole does not have any addictive properties. It is a combination of medication used primarily for the management of intestinal amoebiasis and related gastrointestinal symptoms.

While it is uncommon, some individuals may experience mood changes while taking this combination. If you notice any significant mood changes or related concerns, it would be best to consult your doctor.

There is no known direct impact of this medication on menstruation. However, if you notice any changes in your menstrual cycle or related symptoms, please consult your doctor.

The composition of the medicine depends on the manufacturer. If you prefer to use medicines free from animal products, it's recommended to consult your doctor or pharmacist, who can guide you to the most appropriate choice.

While some natural remedies may offer relief from symptoms like bloating or gas, they may not have the necessary antiprotozoal and antibiotic properties as found in this medication. It is always wise to consult your doctor before starting any natural alternatives.

This medicine combination is primarily aimed at managing amoebiasis and related symptoms. While it is not harmful for a healthy person to take, it is unnecessary and may cause unnecessary side effects. Always consult your doctor before taking any new medication.

Certain foods do not typically interact with this medication. However, you should always follow your doctor's advice about any specific food restrictions or guidelines when taking medication.

Terms & Conditions


Diloxanide + Simethicone + Tinidazole in other salts

ALUMINIUM HYDROXIDE + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + SIMETHICONENORFLOXACIN + TINIDAZOLEALUMINIUM HYDROXIDE + MAGNESIUM ALUMINIUM SILICATE HYDRATE + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + SIMETHICONESIMETHICONEFLUCONAZOLE + TINIDAZOLECLINDAMYCIN + CLOTRIMAZOLE + TINIDAZOLEALPHA AMYLASE + PAPAIN + SIMETHICONETINIDAZOLEDIASTASE + PEPSIN + SIMETHICONEAMOXICILLIN + OMEPRAZOLE + TINIDAZOLEPOVIDONE IODINE + TINIDAZOLEPOVIDONE IODINE + SUCRALFATE + TINIDAZOLEDICYCLOMINE + SIMETHICONEDILL OIL + FENNEL OIL + SIMETHICONEMAGALDRATE + OXETACAINE + SIMETHICONEMAGALDRATE + SIMETHICONEALUMINIUM HYDROXIDE + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + SIMETHICONE + SODIUM CARBOXYMETHYL CELLULOSEALUMINIUM HYDROXIDE + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + OXETACAINE + SIMETHICONEALUMINIUM HYDROXIDE + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + SIMETHICONE + SORBITOLALUMINIUM HYDROXIDE + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + SIMETHICONE + SODIUM ALGINATECIPROFLOXACIN + TINIDAZOLECLARITHROMYCIN + LANSOPRAZOLE + TINIDAZOLEMETRONIDAZOLE + OFLOXACIN + SIMETHICONEDOMPERIDONE + MAGALDRATE + SIMETHICONEALUMINIUM HYDROXIDE + LIQUORICE EXTRACT + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + SIMETHICONECLOTRIMAZOLE + TINIDAZOLEALGINIC ACID + ALUMINIUM HYDROXIDE + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + SIMETHICONEOFLOXACIN + TINIDAZOLEDILOXANIDE + METRONIDAZOLEDOMPERIDONE + RANITIDINE + SIMETHICONEDICYCLOMINE + MAGALDRATE + OXETACAINE + SIMETHICONEDILOXANIDE + TINIDAZOLEDILOXANIDECISAPRIDE + SIMETHICONECLOTRIMAZOLE + LACTOBACILLUS + TINIDAZOLEBILE CONSTITUENTS + PANCREATIN + SIMETHICONEDOXYCYCLINE + TINIDAZOLELACTOBACILLUS + NORFLOXACIN + TINIDAZOLEACTIVATED CHARCOAL + SIMETHICONEDICYCLOMINE + MEFENAMIC ACID + SIMETHICONE
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