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Diclofenac + Serratiopeptidase + Tizanidine

Uses of Diclofenac + Serratiopeptidase + Tizanidine

  • Primarily, Diclofenac + Serratiopeptidase + Tizanidine is prescribed for managing acute musculoskeletal pain and inflammation such as back pain, neck pain, sprains and strains. It belongs to the group of NSAIDs, proteolytic enzymes, and muscle relaxants.

  • It is also used in chronic inflammatory conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, in managing post-operative pain and swelling, as well as in dysmenorrhea (painful menstrual cramps).

Side effects of Diclofenac + Serratiopeptidase + Tizanidine

  • Abdominal pain

  • Dyspepsia (indigestion)

  • Nausea

  • Diarrhoea

  • Headache

  • Dizziness

  • Somnolence (drowsiness)

  • Vertigo

  • Rash

  • Pruritus (itching)

  • Edema (swelling)

How Diclofenac + Serratiopeptidase + Tizanidine works

  • Diclofenac + Serratiopeptidase + Tizanidine is a combination medicine providing analgesic, anti-inflammatory, and muscle relaxant effects.

  • Diclofenac is an NSAID that works by inhibiting enzymes known as COX-1 and COX-2. This reduces the production of prostaglandins, which are chemicals that cause pain and inflammation in the body.

  • Serratiopeptidase is an enzyme. It aids in reducing inflammation and swelling by breaking down proteins that contribute to these conditions. This promotes healing and provides relief from discomfort.

  • Tizanidine is a muscle relaxant. It works on the central nervous system, acting on α2-adrenergic receptors to enhance presynaptic inhibition of motor neurons. This decreases muscle spasms and tightness, helping to alleviate pain caused by muscle-related discomfort.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Diclofenac + Serratiopeptidase + Tizanidine is available for oral administration in the form of tablets.

  • This medication should be swallowed whole with water.

Age and Dose Restrictions

  • This medicine is meant for adults and should not be given to children or adolescents below 18 years of age.

Contraindications

  • This combination is contraindicated in patients allergic to any of its components.

  • It is also contraindicated for those with a history of asthma, urticaria, or other allergic-type reactions following the use of aspirin or other NSAIDs.

  • Patients with active or historical peptic ulcer disease, gastrointestinal bleeding, or perforation should avoid this medicine.

  • It is not suitable for individuals with severe heart failure, or hepatic or renal impairment.

Other Medications to Avoid

  • This combination may interact with other nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen or naproxen), muscle relaxants (like cyclobenzaprine), and anticoagulants (such as warfarin). These interactions can lead to an increased risk of gastrointestinal bleeding, enhanced sedation, or potential alterations in muscle relaxation and pain relief effects.

Overdose and Missed Dose

  • Overdose of Diclofenac + Serratiopeptidase + Tizanidine may lead to severe gastrointestinal issues, increased blood pressure, respiratory depression, or acute renal failure. In such cases, immediate medical attention is crucial.

  • If you miss a dose of this medicine, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage mild gastrointestinal upset from NSAIDs like diclofenac in this combination, consider taking the medicine with food or milk.

  • Drink plenty of water to help reduce the risk of kidney-related side effects from NSAIDs.

Use in Driving and Operating Machinery

  • This medicine may impair your ability to drive or operate heavy machinery due to potential side effects like dizziness or drowsiness caused by tizanidine. Avoid engaging in such activities if you feel affected.

Use in Pregnancy and Lactation

  • Diclofenac + Serratiopeptidase + Tizanidine is not recommended during pregnancy or while breastfeeding. The risks associated with NSAIDs and muscle relaxants in these conditions are significant. Before using this medication during pregnancy or lactation, it is important to consult your doctor.

Caution in Other Conditions

  • Caution is advised when using this medicine in patients with pre-existing liver conditions due to the potential hepatotoxic effects of diclofenac.

  • Individuals with kidney diseases need to be cautious due to the potential nephrotoxic effects of NSAIDs like diclofenac contained in this combination.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet rich in fruits, vegetables, and whole grains to help manage inflammation naturally along with using Diclofenac + Serratiopeptidase + Tizanidine for musculoskeletal conditions.

  • Regular gentle exercises such as walking or swimming can help improve mobility and muscle strength without overstraining the affected areas.

  • Weight management can be crucial in reducing stress on weight-bearing joints, potentially alleviating symptoms of conditions like osteoarthritis.

Frequently asked questions

No, Diclofenac + Serratiopeptidase + Tizanidine is not a steroid. It is a combination of an NSAID, an enzyme, and a muscle relaxant.

Yes, one of the components of this combination, tizanidine, can cause somnolence (drowsiness) or sedation. This could potentially affect your sleep pattern.

No specific data suggests that Diclofenac + Serratiopeptidase + Tizanidine directly affects fertility. However, if you have concerns about this issue, please consult your doctor.

There are no specific dietary restrictions for this medicine, but it is usually recommended to be taken with or after meals to prevent gastric distress.

It is generally safe to take this medication as prescribed by your doctor for the recommended duration. Long-term use should be under the supervision of a doctor due to the risk of side effects.

The exact time for this medication to work can vary between individuals and depends on the condition being managed. However, pain relief is usually seen within a few hours of administration.

This medicine must be taken at times as directed by your doctor.

Terms & Conditions


Diclofenac + Serratiopeptidase + Tizanidine in other salts

ACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENACDICLOFENAC DIETHYLAMINE + LINSEED OIL + MENTHOL + METHYL SALICYLATEDICLOFENAC + PARACETAMOL/ACETAMINOPHENCHLORZOXAZONE + DICLOFENAC + PARACETAMOLDICLOFENAC + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL + SERRATIOPEPTIDASETRYPSIN + BROMELAIN + RUTOSIDE + DICLOFENACSERRATIOPEPTIDASEACECLOFENAC + SERRATIOPEPTIDASEDICLOFENAC + RABEPRAZOLEAMOXICILLIN + CLOXACILLIN + SERRATIOPEPTIDASENIMESULIDE + TIZANIDINEDICLOFENAC + THIOCOLCHICOSIDEDICLOFENAC + NIMESULIDEDICLOFENAC + OMEPRAZOLEDICLOFENAC + EPERISONEAMOXICILLIN + CLOXACILLIN + LACTOBACILLUS + SERRATIOPEPTIDASENIMESULIDE + SERRATIOPEPTIDASENIMESULIDE + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + THIOCOLCHICOSIDEIBUPROFEN + TIZANIDINECAPSAICIN + DICLOFENAC DIETHYLAMINE + LINSEED OIL + MENTHOL + METHYL SALICYLATEDICLOFENAC DIETHYLAMINEDICLOFENAC + LINSEED OIL + MENTHOL + METHYL SALICYLATEDICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATEDICLOFENAC + DICYCLOMINEDICLOFENAC SODIUMDICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATE + OLEUM LINICAPSAICIN + DICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATEDICLOFENAC DIETHYLAMINE + LINSEED OIL + MENTHOL + METHYL SALICYLATE + THIOCOLCHICOSIDEDICLOFENAC SODIUM + MENTHOL + METHYL SALICYLATECAPSAICIN + DICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATE + PREGABALINABSOLUTE ALCOHOL + DICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATECAMPHOR + CAPSAICIN + DICLOFENAC DIETHYLAMINE + EUCALYPTUS OIL + MENTHOL + METHYL SALICYLATEDICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATE + VIRGIN LINSEED OILCAMYLOFIN + DICLOFENACDICLOFENAC + MENTHOL + METHYL SALICYLATEABSOLUTE ALCOHOL + DICLOFENAC SODIUMACECLOFENAC + TIZANIDINEACECLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINEPARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEBROMELAIN + DICLOFENAC + RUTOSIDE + TRYPSIN-CHYMOTRYPSINIBUPROFEN + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + METHOCARBAMOL + PARACETAMOL/ACETAMINOPHENDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TRYPSIN-CHYMOTRYPSINDICLOFENAC + TRYPSIN-CHYMOTRYPSINDICLOFENAC + DICYCLOMINE + PARACETAMOL/ACETAMINOPHENDICLOFENAC + TRAMADOLDICLOFENAC + FAMOTIDINEDICLOFENAC + TIZANIDINEDICLOFENAC + METAXALONELORNOXICAM + PARACETAMOL/ACETAMINOPHEN + SERRATIOPEPTIDASEDICLOFENAC + PARACETAMOL/ACETAMINOPHEN + TIZANIDINECHLORZOXAZONE + DICLOFENAC SODIUM + PARACETAMOL/ACETAMINOPHENROXITHROMYCIN + SERRATIOPEPTIDASEDICLOFENAC + MISOPROSTOLDICLOFENAC + TOLPERISONETIZANIDINEDICLOFENAC + DROTAVERINEDEXTROPROPOXYPHENE + DICLOFENAC + PARACETAMOL/ACETAMINOPHENETORICOXIB + SERRATIOPEPTIDASE
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