Dextropropoxyphene + Diclofenac + Paracetamol/acetaminophen
Uses of Dextropropoxyphene + Diclofenac + Paracetamol/acetaminophen
The primary use of Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen is to manage acute moderate to severe pain. This medication belongs to the class of combination analgesics.
Besides managing post-operative pain, it also helps in relieving acute musculoskeletal pain, short-term dental pain relief, and acute arthritic pain.
Side effects of Dextropropoxyphene + Diclofenac + Paracetamol/acetaminophen
Nausea and vomiting
Constipation
Abdominal pain
Dizziness and drowsiness
Itching and rash
How Dextropropoxyphene + Diclofenac + Paracetamol/acetaminophen works
Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen is an analgesic combination.
Dextropropoxyphene, an opioid analgesic, works by binding to specific receptors in your central nervous system (your brain and spinal cord). By doing this, it blocks the transmission of pain signals, which reduces your perception of pain.
Diclofenac is a nonsteroidal anti-inflammatory medecine (NSAID). It affects substances in your body known as cyclooxygenase enzymes. When these enzymes are blocked, the production of prostaglandins (chemicals that cause pain and inflammation) is reduced, leading to decreased pain and swelling.
Paracetamol/Acetaminophen is an analgesic that also affects the central nervous system. It is thought to inhibit the action of certain enzymes involved in producing prostaglandins. By doing so, it helps to lower pain and reduce fever.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen is available for use via oral route and comes in the form of tablets.
Age and Dose Restrictions
This combination medication is suitable for adults and children aged 16 years and above.
Contraindications
The use of this medicine is contraindicated in patients with known allergies to Dextropropoxyphene, Diclofenac, Paracetamol/Acetaminophen or any of its constituents.
It should not be given to patients suffering from severe respiratory depression, active alcoholism, acute asthma or having a history of medication abuse.
Other Medications to Avoid
This combination can interact with other opioids (such as morphine), sedatives (like benzodiazepines), tranquilisers, anticoagulants (like warfarin), antiplatelet agents (like clopidogrel) and diuretics (like furosemide).
Overdose and Missed Dose
Overdose of this medication can cause severe respiratory depression, hepatotoxicity, gastrointestinal bleeding and even coma. Immediate medical attention is required in such cases.
If a dose is missed, it can be taken as soon as remembered. However, if the time for the next dose is close then the missed dose must be skipped to avoid overdosing.
Management of Side Effects
Most side effects are temporary and generally disappear once the medicine is discontinued. However, if any serious side effects are observed, consulting a doctor immediately is advised.
For managing constipation caused by this medicine, increasing fluid intake and consuming a diet high in fibre can help.
For mild nausea or vomiting, taking this medicine with or after meals can reduce these symptoms.
Use in Driving and Operating Machinery
As this combination can cause drowsiness and dizziness, driving or operating heavy machinery should be avoided after taking this medicine.
Use in Pregnancy and Lactation
The use of this combination is generally not recommended in pregnancy and lactation. It is essential to consult your doctor before using this medicine during these periods.
Caution in Other Conditions
Patients with liver or kidney disease should use this medicine with caution. Also, caution is advised in patients with a history of gastrointestinal disorders such as ulcers and bleeding.
Special Dietary and Lifestyle Recommendations
A balanced diet high in fibre can help manage some of the gastrointestinal side effects of this medication.
Regular but mild exercise can help in managing pain symptoms, which is the primary indication for this medication.
Avoid alcohol consumption while on this medication as it can increase the risk of liver damage and other side effects.
Adequate rest and sleep are crucial as this medication can cause drowsiness.
It is advisable to avoid driving or operating heavy machinery while on this medication due to its potential dizziness effect.
Frequently asked questions
Is Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen a narcotic?
Yes, Dextropropoxyphene is considered a narcotic analgesic, which means it interferes with the communication of pain signals in the nervous system. However, this does not imply that it is illegal or harmful when used as directed by a doctor.
Does Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen affect mood or mental state?
Yes, since the combination contains dextropropoxyphene, an opioid analgesic, it could potentially affect your mood and mental state. It may cause feelings of relaxation and calmness but can also lead to dizziness and drowsiness.
Is Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen safe for long-term use?
This combination is generally intended for short-term use only, specifically for managing acute moderate to severe pain. Long-term use is not recommended due to the potential risks of dependency and adverse effects.
Can I take Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen for headaches?
While this combination can relieve pain, it is typically reserved for moderate to severe pain conditions. For common headaches, over-the-counter analgesics are usually more appropriate. Always consult your doctor before taking any medication.
Can Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen cause weight gain?
There is no direct evidence that this medication causes weight gain. However, each individual may react differently to any medicine, so if you notice unusual weight changes while taking this medication, discuss this with your doctor.
Is it safe to take this medication if I have liver problems?
This medication is not recommended for use in patients with severe hepatic impairment. It is important to consult your doctor if you have liver problems before starting this medication.
Can I exercise while taking Dextropropoxyphene + Diclofenac + Paracetamol/Acetaminophen?
Yes, but keep in mind this medication can cause drowsiness and dizziness. If you experience these side effects, you should avoid activities requiring alertness such as exercise until the effects have worn off.
Dextropropoxyphene + Diclofenac + Paracetamol/acetaminophen in other salts
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