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Dexrabeprazole + Levosulpiride

Uses of Dexrabeprazole + Levosulpiride

  • Dexrabeprazole + Levosulpiride is primarily used for treating acid-related and motility disorders of the upper digestive tract. This combination belongs to the group of proton pump inhibitors and prokinetic medicines.

  • It is also indicated for conditions like Gastroesophageal reflux disease (GERD), Peptic ulcers, Functional dyspepsia, and Zollinger-Ellison syndrome.

Side effects of Dexrabeprazole + Levosulpiride

  • Headache

  • Dizziness

  • Diarrhoea

  • Nausea

  • Abdominal pain

How Dexrabeprazole + Levosulpiride works

  • Dexrabeprazole belongs to a group of medicines called proton pump inhibitors. It works by blocking an enzyme system in the stomach, known as the H+/K+ ATPase system. This action decreases the production of stomach acid, giving ulcers a better chance to heal and reducing symptoms of gastroesophageal reflux disease.

  • Levosulpiride is a prokinetic agent. It improves the movement of the upper digestive tract by acting on certain receptors in the gut. This results in increased contractions in the stomach and intestines, speeding up the emptying process.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Dexrabeprazole + Levosulpiride is available in capsule form for oral administration.

Age and Dose Restrictions

  • This medicine is meant for adult use only and is not recommended for children under 18 years of age.

Contraindications

  • Dexrabeprazole + Levosulpiride is contraindicated in patients with known hypersensitivity to either component or substituted benzimidazoles.

  • Additionally, it is contraindicated in cases of gastrointestinal haemorrhage, mechanical obstruction, or perforation.

Other Medications to Avoid

  • This combination may interact with antiretrovirals (eg., atazanavir and nelfinavir), antiplatelets (eg., clopidogrel), antifungals (eg., ketoconazole and itraconazole), iron supplements (such as ferrous sulphate), and cardiac glycosides (eg., digoxin).

Overdose and Missed Dose

  • An overdose of this medication may cause symptoms like confusion, excessive drowsiness, agitation, increased heart rate, and severe stomach pain. If these occur, it is crucial to seek medical attention promptly.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • In case of mild gastrointestinal disturbances like nausea or abdominal pain, consider taking the capsule with food.

  • For symptoms like dry mouth or a metallic taste, sipping water frequently can be helpful.

Use in Driving and Operating Machinery

  • Dexrabeprazole + Levosulpiride can cause side effects such as dizziness or drowsiness. Therefore, avoid driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

  • The safety of Dexrabeprazole + Levosulpiride during pregnancy and lactation has not been fully established. It is essential to consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with severe liver or kidney impairment should use Dexrabeprazole + Levosulpiride with caution. Adjustments to the dosage might be necessary in these cases due to the potential accumulation of the medicine in the body.

  • Additionally, caution is advised in elderly patients as they may be more susceptible to side effects such as increased prolactin levels or bone fractures.

Special Dietary and Lifestyle Recommendations

  • Eat smaller, more frequent meals instead of three large meals a day.

  • Avoid spicy, fatty, and acidic foods that can trigger digestive discomfort.

  • Reduce caffeine intake which can increase stomach acid.

  • Avoid lying down immediately after meals; wait at least three hours.

  • Elevate the head of your bed by around 6-8 inches to help prevent acid reflux during sleep.

  • Maintain a healthy weight; excess weight can increase abdominal pressure and exacerbate GERD symptoms.

  • Manage stress through relaxation techniques like meditation or yoga; stress can worsen symptoms of dyspepsia and GERD.

Frequently asked questions

No, Dexrabeprazole + Levosulpiride is not a steroid. It is a combination of two medicines: Dexrabeprazole, which is a proton pump inhibitor and Levosulpiride, which is a prokinetic agent.

Dexrabeprazole + Levosulpiride may cause drowsiness in some people. If you experience drowsiness or sleepiness after taking this medication, it is advised to speak to your doctor about it.

There are no known impacts of Dexrabeprazole + Levosulpiride on fertility. However, if you plan to conceive or are experiencing difficulty in conceiving, please consult your doctor.

There are no specific dietary restrictions when taking Dexrabeprazole + Levosulpiride. However, to avoid gastrointestinal disturbances, it is advised to take the medicine with meals.

You should take Dexrabeprazole + Levosulpiride as recommended by your doctor. The need for long-term use should be periodically reassessed.

Acid suppression begins within a few hours of the first dose of Dexrabeprazole + Levosulpiride and symptom relief may be noticed within 2-3 days for GERD and dyspepsia.

Dexrabeprazole + Levosulpiride is not available over the counter. A prescription from a doctor is required to obtain this medication.

Terms & Conditions


Available medicines for DEXRABEPRAZOLE + LEVOSULPIRIDE
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