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Desoximetasone

Uses of Desoximetasone

  • Desoximetasone is primarily used to manage inflammatory and pruritic (itchy) manifestations of corticosteroid-responsive dermatoses. These skin conditions include atopic dermatitis (eczema), contact dermatitis, psoriasis, seborrheic dermatitis, neurodermatitis, lichen simplex chronicus, discoid lupus erythematosus, and certain types of rashes and skin irritation. It belongs to a group of medications known as topical corticosteroids.

Side effects of Desoximetasone

  • Burning sensation

  • Itching

  • Skin irritation

  • Dryness of skin

  • Folliculitis

How Desoximetasone works

  • Desoximetasone is a synthetic corticosteroid.

  • It works by binding to receptors in the skin cells, activating natural substances that reduce inflammation and allergic reactions. This results in decreased swelling, redness, and itching of the skin.

  • The combined actions of Desoximetasone provide vasoconstrictive, anti-inflammatory, immunosuppressive and antiproliferative effects which help manage various corticosteroid-responsive skin conditions.

Certified content

Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • Desoximetasone is available in two different dosage forms for topical application (cream and gel).

Age and Dose Restrictions

  • Desoximetasone is generally prescribed for adults and children aged 12 years and above.

Contraindications

  • Desoximetasone is contraindicated in patients who have a known hypersensitivity to Desoximetasone or any component of its formulation.

  • It is also contraindicated for patients suffering from viral skin infections (like herpes simplex and chickenpox), fungal or bacterial skin infections, tuberculosis of the skin, syphilitic skin infections, and vaccinia and varicella.

Other Medications to Avoid

  • Desoximetasone can interact with immunostimulants (such as aldesleukin), corticosteroid antagonists (like mifepristone), topical calcineurin inhibitors (for example pimecrolimus) and systemic corticosteroids (such as tacrolimus).

Overdose and Missed Dose

  • An overdose of Desoximetasone could cause side effects like irritation, dryness, folliculitis, hypopigmentation, etc. If you notice excessive side effects, please inform your doctor immediately.

  • If you miss a dose of Desoximetasone, apply it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects of Desoximetasone are temporary and generally harmless. They usually resolve once the medicine is discontinued.

  • However, if you experience a burning sensation at the site of application, apply a cold compress to soothe the area.

  • For dryness caused by Desoximetasone, moisturising your skin regularly can help.

  • If you have persistent itching despite using Desoximetasone, taking cool showers and wearing loose clothing can help manage this symptom.

Use in Driving and Operating Machinery

  • As a topical medicine, Desoximetasone does not affect your ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • Use of Desoximetasone during pregnancy should be done only if the potential benefit justifies the potential risk to the foetus.

  • Caution should be exercised while using Desoximetasone during breastfeeding. Always consult your doctor before use.

Caution in Other Conditions

  • Systemic absorption of topical corticosteroids like Desoximetasone can occur, especially under occlusive dressings, in large quantities, or with prolonged use. This could lead to hypothalamic-pituitary-adrenal (HPA) axis suppression. Therefore, caution should be exercised in such conditions.

Special Dietary and Lifestyle Recommendations

  • Keeping your skin clean and moisturised can help manage many skin conditions that Desoximetasone is used to treat.

  • Try to avoid scratching affected areas, as this can exacerbate symptoms and potentially lead to infection.

  • Always protect your skin from excessive exposure to the sun and harsh weather conditions as this could aggravate your skin condition.

  • Maintaining a balanced diet rich in vitamins and minerals can promote healthy skin and aid in the management of skin conditions.

Frequently asked questions

Yes, Desoximetasone is a synthetic corticosteroid. Corticosteroids are a group of medicines that are used to reduce inflammation in the body, especially in the skin.

Yes, Desoximetasone has immunosuppressive effects. This means it can reduce the body's immune response, which is why it helps reduce swelling and redness in inflammatory skin conditions.

Abrupt discontinuation of Desoximetasone may result in a flare-up of the skin condition. It is recommended that you gradually reduce the use of Desoximetasone as per your doctor's advice.

Desoximetasone is not directly associated with impacting mood or sleep. However, if you experience any unusual symptoms while using this medication, consult your doctor immediately.

Desoximetasone is a prescription medication and is not typically available over the counter.

Prolonged use of Desoximetasone, especially under occlusive dressings or in large quantities, can lead to systemic absorption and potential HPA axis suppression.

Desoximetasone is not associated with affecting fertility. If you have concerns about fertility and the use of this medication, consult your doctor for more information.

Terms & Conditions

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