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Dehydroepiandrosterone

Uses of Dehydroepiandrosterone

  • Dehydroepiandrosterone is primarily used for the management of female infertility. It belongs to the group of endogenous steroid hormones.

Side effects of Dehydroepiandrosterone

  • Acne

  • Oily skin

  • Hair loss

  • Excessive hair growth

  • Mood changes like irritability and aggressiveness

How Dehydroepiandrosterone works

  • Dehydroepiandrosterone is an endogenous steroid hormone.

  • It serves as a precursor for the production of other vital hormones in the body. After ingesting Dehydroepiandrosterone, the body converts it into more potent hormones like testosterone and estradiol. This conversion is facilitated by specific enzymes present in the body, such as 3β-hydroxysteroid dehydrogenase. These increased hormone levels are responsible for the fertility-enhancing effects seen in women who take Dehydroepiandrosterone. At higher doses, Dehydroepiandrosterone can also independently interact with androgen and oestrogen receptors, potentially contributing to its effects.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Dehydroepiandrosterone is available in an oral formulation, which is taken as tablets.

Age and Dose Restrictions

  • Dehydroepiandrosterone is intended for adult use only. It is not recommended for children or teenagers under the age of 18 years.

Contraindications

  • Individuals with hormone-sensitive cancers, like breast, ovarian, and prostate cancer should avoid this medicine.

  • It is also contraindicated in people with liver disease and mood disorders like depression and anxiety.

Other Medications to Avoid

  • Dehydroepiandrosterone can interact with antidepressants (such as fluoxetine), antiplatelet medicines (like aspirin), seizure medications (like lamotrigine) and certain HIV medications (like ritonavir).

Overdose and Missed Dose

  • An overdose of Dehydroepiandrosterone could lead to hormonal imbalances resulting in various side effects, including acne, hair loss, weight gain, mood changes and menstrual irregularities. If you suspect an overdose, seek medical help immediately.

  • If you miss a dose of Dehydroepiandrosterone, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage side effects such as dry skin and constipation.

  • Try taking the medicine with food if it causes stomach upset.

Use in Driving and Operating Machinery

  • Dehydroepiandrosterone may affect your ability to drive or operate heavy machinery due to potential mood changes. It is advisable to avoid such activities until you know how this medication affects you.

Use in Pregnancy and Lactation

  • Dehydroepiandrosterone is not recommended for use during pregnancy and breastfeeding. Always consult your doctor before taking this medication if you are pregnant, planning a pregnancy, or breastfeeding.

Caution in Other Conditions

  • Patients with liver disease should take caution when using Dehydroepiandrosterone due to the potential for liver damage.

  • Individuals with mood disorders such as depression and anxiety should also exercise caution due to the potential for mood changes.

Special Dietary and Lifestyle Recommendations

  • Dietary habits are key to maintaining a hormonal balance. Consuming a balanced diet rich in fruits, vegetables, whole grains, lean proteins and healthy fats can help support overall health while taking Dehydroepiandrosterone.

  • Regular physical activity is important for overall health and particularly beneficial for managing hormonal imbalances. Incorporate moderate aerobic activities into your daily routine.

Frequently asked questions

Yes, Dehydroepiandrosterone is a type of steroid hormone that is produced naturally by the body's adrenal glands. It acts as a precursor for the synthesis of other hormones like androgens and estrogens.

Yes, Dehydroepiandrosterone can potentially influence mood. Some people report improvements in their mood and memory after taking it, but these benefits are not consistently supported by scientific evidence.

Yes, Dehydroepiandrosterone is often used medically to help manage female infertility. It aids in the production of estrogen and testosterone, which are key hormones in egg development and fertility.

The safety of daily Dehydroepiandrosterone usage depends on the dose and duration of treatment, along with individual health factors. It is vital to follow the dose prescribed by your doctor.

Dehydroepiandrosterone gets rapidly absorbed in the body with peak levels occurring about an hour after ingestion. The timeframe for experiencing effects can vary depending on the individual and the condition being managed.

The best time to take Dehydroepiandrosterone should be decided in consultation with your doctor, as it can depend on various factors including the condition being managed and individual health factors.

Dehydroepiandrosterone can interact with many medications such as antidepressants, diabetes medications, and blood thinners, among others. Therefore, it should only be used under medical supervision.

Terms & Conditions


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