Dapagliflozin + Vildagliptin
Uses of Dapagliflozin + Vildagliptin
Dapagliflozin + Vildagliptin is primarily used to manage adults with type 2 diabetes mellitus. It belongs to the group of sodium-glucose co-transporter 2 (SGLT2) inhibitors and dipeptidyl peptidase-4 (DPP-4) inhibitors.
Side effects of Dapagliflozin + Vildagliptin
Female genital mycotic infections
Nasopharyngitis
Urinary tract infections
Headache
Upper respiratory tract infections
How Dapagliflozin + Vildagliptin works
Dapagliflozin + Vildagliptin is an antidiabetic combination.
Dapagliflozin belongs to a category of medicines known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by obstructing the reabsorption of glucose in the kidneys, leading to the expulsion of surplus glucose through urine. This process helps in lowering blood sugar levels.
Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It acts by slowing down the process of inactivation of certain hormones known as incretin hormones, enhancing insulin secretion from the pancreas and reducing glucagon secretion from the liver in a glucose-dependent manner. This helps in maintaining stable blood sugar levels.
Certified content
Written By
BDS, MDS
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Dapagliflozin + Vildagliptin can be taken orally (tablet).
Age and Dose Restrictions
Dapagliflozin + Vildagliptin is intended for use by adults aged 18 and older.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to dapagliflozin, vildagliptin, or any component of the formulation. It should not be used in patients with severe renal impairment, end-stage renal disease (ESRD), or those undergoing dialysis. Patients with type 1 diabetes mellitus or diabetic ketoacidosis should also refrain from using this medication.
Other Medications to Avoid
Dapagliflozin + Vildagliptin may interact with diuretics (such as furosemide and hydrochlorothiazide), insulin and insulin secretagogues (such as sulfonylureas like glipizide and glyburide).
Overdose and Missed Dose
In case of an overdose of Dapagliflozin + Vildagliptin, immediate medical assistance should be sought. Overdose symptoms may include dizziness, confusion, or fainting.
If a dose is missed, it should be taken as soon as remembered. However, if it's close to the scheduled time for the next dose, the missed dose should be skipped.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If you experience dizziness or light-headedness, sit or lie down until the symptoms pass.
Drinking plenty of water can help to manage some side effects such as dry mouth and prevent dehydration which could be a side effect due to increased urination.
Use in Driving and Operating Machinery
Dapagliflozin + Vildagliptin may cause dizziness or fatigue. If these symptoms occur, it is advised to refrain from driving or operating heavy machinery until one feels alert and safe.
Use in Pregnancy and Lactation
The use of Dapagliflozin + Vildagliptin during pregnancy and breastfeeding is generally not recommended due to potential risks to the mother and baby. Always consult your doctor before using this medicine during these periods.
Caution in Other Conditions
Patients with moderate renal impairment should exercise caution when using this medicine.
It's also advisable for patients with hepatic impairments to discuss the risks and benefits with their doctor prior to starting this medication.
Special Dietary and Lifestyle Recommendations
Regular monitoring of blood sugar levels is advised.
Frequently asked questions
Is Dapagliflozin + Vildagliptin a steroid?
No, Dapagliflozin + Vildagliptin is not a steroid. It is a combination medicine used to manage blood sugar levels in adults with type 2 diabetes mellitus.
Will taking Dapagliflozin + Vildagliptin affect my sleep?
There is no specific connection between Dapagliflozin + Vildagliptin and sleep disturbances. However, changes to your sleeping pattern or any concerns should be discussed with your doctor.
Can Dapagliflozin + Vildagliptin affect fertility?
The combination of Dapagliflozin + Vildagliptin is not known to affect fertility. However, if you are planning a pregnancy, it is always wise to consult your doctor before taking any medication.
Can I take Dapagliflozin + Vildagliptin beyond the prescribed duration?
It is not recommended to take Dapagliflozin + Vildagliptin beyond the duration prescribed by your doctor. Prolonged use may lead to potential health risks.
Will Dapagliflozin + Vildagliptin affect my mood or behaviour?
The combination of Dapagliflozin + Vildagliptin is not known to cause any mood or behavioural changes. If you notice any such changes, consult your doctor immediately.
Is Dapagliflozin + Vildagliptin available over the counter, or do I need a prescription?
Dapagliflozin + Vildagliptin is a prescription medicine and is not available over the counter.
Does Dapagliflozin + Vildagliptin increase weight?
Dapagliflozin + Vildagliptin is generally not associated with weight gain. Dapagliflozin often leads to weight loss, while vildagliptin typically has a neutral effect on weight.
Dapagliflozin + Vildagliptin in other salts
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