Home/Drugs By Ailments / Cyanocobalamin / Vitamin B12 + Folic Acid + Iron

Cyanocobalamin / Vitamin B12 + Folic Acid + Iron

Uses of Cyanocobalamin / Vitamin B12 + Folic Acid + Iron

  • Cyanocobalamin / Vitamin B12 + Folic Acid + Iron is primarily used to manage and prevent anaemias and other conditions caused by deficiencies in these nutrients. It is an essential nutrient supplement.

  • Additionally, this combination is also often prescribed to pregnant women to support healthy fetal development and prevent birth defects like neural tube defects.

Side effects of Cyanocobalamin / Vitamin B12 + Folic Acid + Iron

  • Nausea

  • Vomiting

  • Diarrhoea

  • Headache

  • Dark stools

How Cyanocobalamin / Vitamin B12 + Folic Acid + Iron works

  • Cyanocobalamin, the synthetic form of Vitamin B12, converts into active forms in the body. It plays a key role in the formation of red blood cells, DNA synthesis, metabolism of fatty acids, and proper nerve function.

  • Folic Acid, also known as Vitamin B9, transforms in the body to become active tetrahydrofolate. It acts as a crucial coenzyme in DNA and RNA synthesis, maturation of red blood cells, and metabolism of the amino acid homocysteine.

  • Iron is integrated into haeme in red blood cells and muscle cells. It acts as a vital cofactor for enzymes involved in oxidative metabolism and many other functions. In unison, these nutrients work to prevent or correct deficiencies that can cause various types of anaemia and other health issues.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • The combination of Cyanocobalamin / Vitamin B12 + Folic Acid + Iron is available for use via oral route in the form of tablets, capsules, and liquids. This combination is also available as an injection for intravenous or intramuscular administration.

Age and Dose Restrictions

  • This supplement combination is intended for use in adults and children above the age of 12 years.

Contraindications

  • Cyanocobalamin / Vitamin B12 + Folic Acid + Iron is contraindicated in patients with known allergies to any of the components.

  • It is also contraindicated in patients with conditions like hemosiderosis or hemochromatosis, which are iron overload disorders.

Other Medications to Avoid

  • This combination may interact with proton pump inhibitors (such as omeprazole and lansoprazole), antacids (like aluminium hydroxide, Magnesium Hydroxide), levothyroxine, tetracyclines (like doxycycline, minocycline), fluoroquinolones (such as ciprofloxacin, ofloxacin), and H2 blockers (like famotidine, ranitidine).

Overdose and Missed Dose

  • An overdose of this medication may cause symptoms like nausea, vomiting, diarrhoea, headache and dizziness. If such symptoms occur, consult your doctor immediately.

  • If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Nausea or upset stomach due to iron can be managed by taking the medicine with food.

  • If constipation occurs due to iron intake, increasing fluid and fibre intake can help.

Use in Driving and Operating Machinery

  • Cyanocobalamin / Vitamin B12 + Folic Acid + Iron does not usually affect the ability to drive or operate machinery. However, if you feel dizzy or sleepy after taking this medicine, avoid these activities.

Use in Pregnancy and Lactation

  • Pregnant and breastfeeding women should use this combination supplement only if prescribed by a doctor.

Caution in Other Conditions

  • Patients with malabsorption syndromes should exercise caution when taking this supplement as oral absorption may be impaired.

Special Dietary and Lifestyle Recommendations

  • Avoid consuming foods rich in phytates, tannins and phosphates at the same time as iron as they may decrease absorption.

  • Consider having vitamin C-rich foods with your meals to enhance iron absorption.

Frequently asked questions

No, Cyanocobalamin / Vitamin B12 + Folic Acid + Iron is not a steroid. It is a combination of essential nutrients used to manage deficiencies and prevent anaemias.

Cyanocobalamin (Vitamin B12) + folic acid + iron generally don’t directly affect sleep. However, if you experience unusual changes in sleep patterns, consult your healthcare provider.

Cyanocobalamin (Vitamin B12) + folic acid + iron generally support overall reproductive health and is not known to negatively affect fertility. If you have specific concerns, it's best to consult with your healthcare provider.

Yes, it is safe to take Cyanocobalamin / Vitamin B12 + Folic Acid + Iron daily as per your doctor's recommendation. However, excessive intake over time can lead to certain adverse effects such as iron overload.

The time it takes to see improvement after starting this medication can vary from a few days to weeks depending on the severity of the deficiency. Complete repletion of body stores may take several months.

There are no specific timing requirements for taking this combination. However, it is generally advised to follow the regimen prescribed by your doctor. Iron is often better absorbed when taken with food.

Cyanocobalamin (Vitamin B12) + folic acid + iron typically don’t cause changes in menstruation. However, if you notice any unusual changes, consult your healthcare provider for personalised advice.

Terms & Conditions


Cyanocobalamin / Vitamin B12 + Folic Acid + Iron in other salts

ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE) + VITAMIN D3 (CHOLECALCIFEROL)ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEASCORBIC ACID + BIOTIN + CALCIUM PANTOTHENATE + FOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + RIBOFLAVIN + THIAMINE MONONITRATE + ZINC SULPHATEASCORBIC ACID + ELEMENTAL MANGANESE + ELEMENTAL SELENIUM + ELEMENTAL ZINC + FOLIC ACID + NIACINAMIDE + PYRIDOXINE HYDROCHLORIDE + RIBOFLAVIN / VITAMIN B2 + VITAMIN A + VITAMIN EBIOTIN + CALCIUM PANTOTHENATE + COPPER SULPHATE + COPPER SULPHATE PENTAHYDRATE + CYANOCOBALAMIN / VITAMIN B12 + FERROUS SULPHATE + MAGNESIUM OXIDE + MAGNESIUM SULPHATE MONOHYDRATE + NICOTINAMIDE + PYRIDOXINE HYDROCHLORIDE + RIBOFLAVIN / VITAMIN B2 + SODIUM BORATE + SODIUM MOLYBDATE DIHYDRATE + THIAMINE MONONITRATE + TOCOPHERYL ACETATE + TOTAL PHOSPHOROUS + TRIBASIC CALCIUM PHOSPHATE + VITAMIN A / RETINOL + VITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + ZINC SULPHATEBIOTIN + CYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL CHROMIUM + ELEMENTAL COPPER + ELEMENTAL MANGANESE + FOLIC ACID + GRAPE SEED EXTRACT + IODINE + MAGNESIUM + RIBOFLAVIN / VITAMIN B2 + SELENIUM + THIAMINE / VITAMIN B1 + VITAMIN A / RETINOL + VITAMIN B3 / NIACIN + VITAMIN B5 / PANTOTHENIC ACID + VITAMIN B6 / PYRIDOXINE + VITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + VITAMIN E + ZINCCALCIUM PHOSPHATE + COPPER SULPHATE PENTAHYDRATE + CYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + FOLIC ACID + LIGHT MAGNESIUM OXIDE + NICOTINAMIDE + POTASSIUM IODIDE + VITAMIN A + VITAMIN B1 + VITAMIN B2 + VITAMIN D3 (CHOLECALCIFEROL) + ZINC SULPHATE MONOHYDRATECHROMIUM PICOLINATE + CYANOCOBALAMIN + ELEMENTAL SELENIUM + FOLIC ACID + NICOTINAMIDE + PYRIDOXINE HYDROCHLORIDE + ZINC SULPHATE MONOHYDRATEFERROUS ASCORBATE + FOLIC ACIDFOLIC ACIDRIBOFLAVIN + PYRIDOXINE + VITAMIN B12 + NIACINAMIDE + CALCIUM + FOLIC ACID + BIOTIN + ASCORBIC ACIDFRUSEMIDE + SPIRONOLACTONESPIRONOLACTONE + TORSEMIDEBIOTIN + FOLIC ACIDALFACALCIDOL + DOCOSAHEXAENOIC ACID + EICOSAPENTAENOIC ACID + ELEMENTAL BORON + ELEMENTAL CALCIUM + FOLIC ACID + METHYLCOBALAMINCARBONYL IRON + FOLIC ACID + ZINC SULPHATEALPHA LIPOIC ACID + BENFOTIAMINE + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEBORON + CALCITRIOL/ CHOLECALCIFEROL + CALCIUM CARBONATE + DOCOSAHEXAENOIC ACID + EICOSAPENTAENOIC ACID + FOLIC ACID + METHYLCOBALAMINFOLIC ACID + IRON + ZINCDOCOSAHEXAENOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)DHA + FOLIC ACIDALPHA LIPOIC ACID + BENFOTIAMINE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)FERROUS FUMARATE + FOLIC ACID + ZINC SULPHATEALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 / PYRIDOXINECARBONYL IRON + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + ZINC SULPHATEIRONFOLIC ACID + IRONCYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL IRON + FOLIC ACID + VITAMIN C / ASCORBIC ACID + ZINCDOCOSAHEXAENOIC ACID + FOLIC ACIDCYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + VITAMIN B6 / PYRIDOXINECYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACIDFOLIC ACID + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2BENFOTIAMINE + FOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 / PYRIDOXINEFOLIC ACID + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEFOLIC ACID + MYO INOSITOLELEMENTAL IRON + FOLIC ACID + VITAMIN C / ASCORBIC ACIDELEMENTAL IRONCARBONYL IRON + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + VITAMIN C / ASCORBIC ACID + ZINC SULPHATEALPHA LIPOIC ACID + BENFOTIAMINE + BIOTIN + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)ELEMENTAL IRON + FOLIC ACID + GLYCINEALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + THIAMINE MONONITRATE + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + BIOTIN + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + BENFOTIAMINE + BIOTIN + ELEMENTAL CHROMIUM + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + CHROMIUM PICOLINATE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + SELENOMETHIONINE + ZINC MONOMETHIONINECYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + IRON + ZINCELEMENTAL IRON + FOLIC ACIDALPHA LIPOIC ACID + BENFOTIAMINE + CHROMIUM PICOLINATE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINECYANOCOBALAMIN / VITAMIN B12 + PREGABALINALPHA LIPOIC ACID + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + BENFOTIAMINE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINE + VITAMIN D3 (CHOLECALCIFEROL)BIOTIN + CALCIUM PANTOTHENATE + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINE + VITAMIN C / ASCORBIC ACIDCYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + SODIUM FEREDETATECYANOCOBALAMIN / VITAMIN B12 + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + BENFOTIAMINE + CHROMIUM POLYNICOTINATE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + SELENIUM DIOXIDECYANOCOBALAMIN / VITAMIN B12 + FERROUS FUMARATE + FOLIC ACID + ZINC SULPHATEELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACIDFOLIC ACID + METHYLCOBALAMINADENOSYLCOBALAMIN + CARBONYL IRON + FOLIC ACID + ZINC SULPHATEFERROUS FUMARATE + FOLIC ACIDALPHA LIPOIC ACID + BENFOTIAMINE + BIOTIN + CHROMIUM PICOLINATE + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + LACTIC ACID BACILLUSALPHA LIPOIC ACID + BENFOTIAMINE + CHROMIUM PICOLINATE + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + BENFOTIAMINE + CHROMIUM PICOLINATE + FOLIC ACID + METHYLCOBALAMIN + MYO INOSITOL + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINE + VITAMIN D3 (CHOLECALCIFEROL)IRON POLYMALTOSE COMPLEXFOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE) + VITAMIN D3 (CHOLECALCIFEROL)CYANOCOBALAMIN + ELEMENTAL IRON + FOLIC ACID + VITAMIN C / ASCORBIC ACIDCYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL IRON + FOLIC ACID + VITAMIN C / ASCORBIC ACIDELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACID + METHYLCOBALAMINBORON + CALCITRIOL/ CHOLECALCIFEROL + CALCIUM CARBONATE + DHA / DOCOSAHEXAENOIC ACID + EPA / EICOSAPENTAENOIC ACID + FOLIC ACID + METHYLCOBALAMINALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PYRIDOXINE HYDROCHLORIDE + THIAMINE MONONITRATEBENFOTIAMINE + FOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 (PYRIDOXINE)IRON POLYSACCHARIDE COMPLEXALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PYRIDOXINE HYDROCHLORIDE + VITAMIN D3 (CHOLECALCIFEROL)FERROUS ASCORBATE + FOLIC ACID + ZINC SULPHATECYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + NICOTINAMIDECYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL IRON + FOLIC ACIDIRON FERROUSELEMENTAL IRON + FOLIC ACID + METHYLCOBALAMINCYANOCOBALAMIN / VITAMIN B12 + FERRIC AMMONIUM CITRATE + FOLIC ACIDFOLIC ACID + L ARGININE + ZINCCYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + NIACINAMIDE + VITAMIN C / ASCORBIC ACIDIRON SUCROSEFOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN C / ASCORBIC ACIDIRON ISOMALTOSIDEFOLIC ACID + METHYLCOBALAMIN + NIACINAMIDECYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINECALCIUM + CYANOCOBALAMIN / VITAMIN B12 + VITAMIN D3 (CHOLECALCIFEROL)FOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINECUPRIC SULPHATE + CYANOCOBALAMIN + FERRIC AMMONIUM CITRATE + FOLIC ACID + MANGANESE SULPHATECALCIUM + IRON + POTASSIUM + SODIUMCALCIUM + IRON + VITAMIN A / RETINOL + VITAMIN C / ASCORBIC ACIDCALCIUM + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + IRON + PHOSPHORUS + POTASSIUM + SODIUM + VITAMIN A + VITAMIN B1 + VITAMIN B2 + VITAMIN B3 + VITAMIN B5 (PANTOTHENIC ACID) + VITAMIN B6 (PYRIDOXINE) + VITAMIN C / ASCORBIC ACID + VITAMIN EELEMENTAL ZINC + FOLIC ACID + L ARGININE + PROANTHOCYANIDINFOLIC ACID + MYO INOSITOL + VITAMIN D3 (CHOLECALCIFEROL)CYANOCOBALAMIN / VITAMIN B12 + FERROUS ASCORBATE + FOLIC ACIDBETA-CAROTENE + BIOTIN + CALCITRIOL/ CHOLECALCIFEROL + CHROMIUM + CYANOCOBALAMIN / VITAMIN B12 + INOSITOL + IODINE + LYSINE + MANGANESE + MOLYBDENUM + NIACINAMIDE + SELENIUM + VITAMIN B6 / PYRIDOXINE + ZINCCYANOCOBALAMIN + ELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACIDCYANOCOBALAMIN + FERRIC AMMONIUM CITRATE + FOLIC ACIDCYANOCOBALAMIN + ELEMENTAL IRON + FOLIC ACIDCYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + L-LYSINE + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINECYANOCOBALAMIN / VITAMIN B12 + L-LYSINE + NIACINAMIDE + VITAMIN B6 / PYRIDOXINEFERROUS ASCORBATE + FOLIC ACID + METHYLCOBALAMINCYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + SODIUM FEREDETATE + ZINC SULPHATEELEMENTAL ZINC + FERROUS ASCORBATE + FOLIC ACIDCYANOCOBALAMIN / VITAMIN B12 + FOLIC ACIDSPIRONOLACTONEDOXYLAMINE + FOLIC ACID + VITAMIN B6 / PYRIDOXINEFOLIC ACID + L-CARNITINE / LEVOCARNITINE + METHYLCOBALAMINCHROMIUM PICOLINATE + CYANOCOBALAMIN + ELEMENTAL SELENIUM + FOLIC ACID + NICOTINAMIDE + VITAMIN B6 / PYRIDOXINE + ZINC SULPHATE MONOHYDRATEBUSPIRONEELEMENTAL CALCIUM + FOLIC ACID + VITAMIN D3 (CHOLECALCIFEROL)ALPHA LIPOIC ACID + BENFOTIAMINE + CALCIUM CARBONATE + CHROMIUM PICOLINATE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINE + VITAMIN D3 (CHOLECALCIFEROL)CALCITRIOL/ CHOLECALCIFEROL + CALCIUM ASPARTATE + CALCIUM OROTATE + FOLIC ACID + HYDROXOCOBALAMIN + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + ZINCALPHA LIPOIC ACID + FOLIC ACID + MECOBALAMIN + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 / PYRIDOXINEFOLIC ACID + L-ORNITHINEL-ASPARTATE + METADOXINE + SILYMARIN + VITAMIN B6 / PYRIDOXINEFERROUS ASCORBATE + FOLIC ACID + ZINCFERROUS ASCORBATE + FOLIC ACID + ZINC SULPHATE MONOHYDRATEFOLIC ACID + LACTIC ACID BACILLUS + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2FERROUS BISGLYCINATE + FOLIC ACID + METHYLCOBALAMIN + ZINC BISGLYCINATEFOLIC ACID + METHYLCOBALAMIN + PYRIDOXINE HYDROCHLORIDECYANOCOBALAMIN / VITAMIN B12 + NORTRIPTYLINE + PREGABALINCALCIUM CITRATE + FOLIC ACID + VITAMIN D3 (CHOLECALCIFEROL)CYANOCOBALAMIN + ELEMENTAL IRON + FOLIC ACID + ZINCDEHYDROEPIANDROSTERONE + FOLIC ACID + VITAMIN D3 (CHOLECALCIFEROL)ADENOSYLCOBALAMIN + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B1 + VITAMIN B2 + VITAMIN B6 (PYRIDOXINE)CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + IRON PYROPHOSPHATE LIPOSOMAL + VITAMIN C / ASCORBIC ACIDDOXYLAMINE + FOLIC ACID + VITAMIN B6 (PYRIDOXINE)BORON + CALCITRIOL/ CHOLECALCIFEROL + CALCIUM CARBONATE + FOLIC ACID + METHYLCOBALAMIN + OMEGA 3 FATTY ACIDALPHA LIPOIC ACID + BENFOTIAMINE + CALCIUM CARBONATE + CHROMIUM 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