Clobetasol Propionate + Iodochlorhydroxyquinoline + Ketoconazole + Neomycin + Tolnaftate is primarily used to manage various skin infections caused by bacteria and fungi. It belongs to a group of medicines which includes a corticosteroid, antibacterial and antifungal agents.
Additionally, it also manages conditions like inflamed, itchy and infected eczema or dermatitis, ringworm and other tinea fungal infections of the skin, secondary bacterial infections complicating fungal skin infections and inflamed seborrheic dermatitis with secondary infection.
Local skin reactions like burning
Stinging sensation on application
Itching at the site of application
Skin irritation
Redness at the application site
Clobetasol Propionate + Iodochlorhydroxyquinoline + Ketoconazole + Neomycin + Tolnaftate is a combination medicine that has anti-inflammatory, antifungal and antibacterial properties.
Clobetasol Propionate is a topical corticosteroid. It reduces inflammation and itching by suppressing immune system processes that cause inflammation.
Ketoconazole inhibits the synthesis of ergosterol, a key component of fungal cell membranes. This results in the leakage of cellular contents, disrupting fungal growth.
Tolnaftate interferes with squalene epoxidase, an enzyme vital for fungal cell membrane synthesis. Consequently, it disrupts the integrity of the fungal cell wall.
Neomycin binds to the 30S ribosomal subunit in susceptible bacteria, interrupting protein synthesis. This causes bacterial death.
Iodochlorhydroxyquinoline disrupts bacterial DNA synthesis and cell membranes, effectively combating bacterial infections.
Doctor of Medicine
BMS, FMC, MD Resident
Clobetasol Propionate + Iodochlorhydroxyquinoline + Ketoconazole + Neomycin + Tolnaftate is available for use via topical route in the form of cream, ointment, lotion, and gel.
This combination medicine is suitable for adults and children above 2 years of age.
This medicine is contraindicated in patients with known hypersensitivity to any of the ingredients
It is also contraindicated for viral skin infections like herpes simplex, vaccinia, varicella, tuberculous or syphilitic skin infections, and fungal infections not susceptible to ketoconazole or tolnaftate.
Clobetasol Propionate + Iodochlorhydroxyquinoline + Ketoconazole + Neomycin + Tolnaftate can interact with oral corticosteroids (like prednisone, dexamethasone) and immunosuppressants (such as cyclosporine, tacrolimus).
It is also important to inform your doctor about any other medications you are taking.
Overuse or accidental oral consumption of this medicine may lead to excessive absorption of active ingredients leading to systemic side effects. If such a situation occurs, consult your doctor immediately.
In case you miss a dose, apply the missed dose as soon as you remember. If it is near the time for your next dose, skip the missed dose and continue with your regular schedule.
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Use a mild, fragrance-free moisturiser to relieve dryness or irritation caused by the medicine.
Ensure that you do not apply more medicine than recommended to avoid local skin reactions.
This medicine does not affect your ability to drive or operate machinery. However, if you experience any local reactions or allergic symptoms, avoid such tasks until they resolve.
Consult your doctor before using this medicine during pregnancy or while breastfeeding.
Patients with thinning of the skin (atrophy) at the treatment site should use this combination with caution.
Also, patients with adrenal gland problems should be monitored closely by their doctor while using this medication.
Maintain good skin hygiene to prevent reinfection and spread of infection.
Avoid scratching or touching the affected area to prevent irritation and secondary infection.
Wear clean, breathable clothing to avoid moisture build-up that can worsen fungal infections.
Frequently asked questions
Yes, although rare, an allergic reaction can be caused by this medicine. Signs of an allergic reaction include rash, itching, swelling or severe dizziness. If you notice such symptoms, stop using the medicine and consult your doctor immediately.
This medication should be used with caution on the face as the risk of adverse effects is higher. It should not be used for a prolonged period, and always under the supervision of a doctor.
Yes, skin discoloration is a possible side effect of this medication. It can cause either lightening or darkening of the skin depending on your skin type and the duration of usage.
Children are more prone to side effects of this medication. Hence, it should be used with caution in children and only under the supervision of a doctor.
Pregnant women should use this medication only if the benefits outweigh the risks. It is advisable to consult your doctor before using this medication during pregnancy.
Yes. It is recommended to cleanse and dry the skin before applying the medication to increase its effectiveness and prevent the spread of infection.
No, this combination medicine is not used for treating viral skin infections like herpes simplex, vaccinia, varicella. Consult your doctor if you have a viral skin infection.
Clobetasol Propionate + Iodochlorhydroxyquinoline + Ketoconazole + Neomycin + Tolnaftate in other salts
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