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Cisplatin

Uses of Cisplatin

  • Cisplatin is primarily used in the management of various types of cancer including metastatic testicular tumours, advanced ovarian tumours, cervical cancer, bladder cancer, head and neck cancer, and small cell lung cancer. It belongs to the group of chemotherapeutic agents.

Side effects of Cisplatin

  • Nausea and vomiting

  • Diarrhoea

  • Fatigue

  • Hair loss

  • Numbness or tingling in hands and feet

How Cisplatin works

  • Cisplatin is a chemotherapeutic agent.

  • It functions by forming bonds with the DNA in cancer cells. This disrupts DNA replication and transcription, which are vital processes for cell growth and multiplication. The resulting interference causes cancer cells to undergo apoptosis, which is a form of programmed cell death. By triggering cell death in this way, Cisplatin effectively hampers the growth and spread of certain types of cancer. pointer.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Divya Chauhan
Dr. Divya Chauhan Medical Writer & Reviewer| 6 years

BAMS, APG, PG

Expert Advice

Dosage Forms Available

  • Cisplatin is available for intravenous use only (injection).

Age and Dose Restrictions

  • Cisplatin is mainly used for adults.

Contraindications

  • Cisplatin is contraindicated in patients with known hypersensitivity to Cisplatin or other platinum-containing compounds. It should not be used in patients with severe renal impairment or severe bone marrow depression.

Other Medications to Avoid

  • Cisplatin may interact with aminoglycoside antibiotics (e.g., gentamicin, amikacin), loop diuretics (e.g., furosemide, torsemide), and anticonvulsants (e.g., phenytoin, phenobarbital).

Overdose and Missed Dose

  • An overdose of Cisplatin can potentially lead to severe side effects such as kidney damage and hearing loss. If you suspect an overdose, consult your doctor immediately.

  • If you miss a dose of Cisplatin, contact your doctor for further instructions. Do not double up on doses to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing Cisplatin. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of fluids can help manage nausea and vomiting.

  • Resting and limiting physical activity can help manage fatigue.

  • Wearing comfortable footwear and clothing can help manage numbness or tingling in hands and feet.

Use in Driving and Operating Machinery

  • Cisplatin may cause side effects such as fatigue and dizziness. Therefore, driving or operating heavy machinery should be avoided after taking Cisplatin.

Use in Pregnancy and Lactation

  • Cisplatin is not recommended during pregnancy and lactation unless prescribed by the doctor after assessing the risks involved. Consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with pre-existing renal impairment should exercise caution when receiving Cisplatin. It is also necessary to monitor renal function closely during treatment with Cisplatin.

Special Dietary and Lifestyle Recommendations

  • Add ginger and turmeric to meals, as they have anti-nausea properties and may help alleviate chemotherapy-induced nausea and inflammation.

  • Avoid extremely cold foods or drinks, as some patients may develop cold sensitivity during Cisplatin treatment.

  • Incorporate electrolyte-rich beverages, like coconut water or oral rehydration solutions, to balance the body's electrolytes, which can be affected by Cisplatin.

  • Regular hearing checks are recommended as Cisplatin may cause hearing loss.

Frequently asked questions

Cisplatin does not directly affect sleep. However, some side effects like fatigue and nausea might indirectly influence your sleep pattern. However, if you have concerns, consult your doctor.

Yes, Cisplatin can potentially affect fertility in both men and women. It is advisable to discuss this with your doctor before starting therapy.

The frequency of taking Cisplatin would depend on your doctor's prescription considering your medical condition and response to treatment.

Cisplatin starts to work soon after administration but the extent of its effect varies for each individual and type of cancer.

The timing of Cisplatin administration will be determined by your healthcare professional according to your treatment plan.

The duration of treatment with Cisplatin varies depending on the type of cancer being managed and the individual patient's response to treatment. This should be discussed with your doctor.

Cisplatin is a potent chemotherapeutic agent and is not available over the counter. It must be prescribed by a doctor and administered under medical supervision.

Terms & Conditions

Available medicines for CISPLATIN
Cistero 10mg Injection 10ml
Cistero 10mg Injection 10ml
Hetero Healthcare Ltd
Pack of 10 ML
₹106.60
MRP ₹130.00
18.00% OFF
Cisplan 50 MG Injection 1
Cisplan 50 MG Injection 1
Natco Pharma Ltd
Pack of 1 UNIT
₹299.14
MRP ₹364.80
18.00% OFF
Platinex 10 MG Injection 10 ML
Platinex 10 MG Injection 10 ML
Khandelwal Laboratories Ltd
Pack of 10 ML
₹52.71
MRP ₹64.28
18.00% OFF
Cisget 50 MG Injection 1
Cisget 50 MG Injection 1
Getwell Pharmaceutical Pvt Ltd
Pack of 1 UNIT
₹348.50
MRP ₹425.00
18.00% OFF
Celplat 50 MG Injection 1
Celplat 50 MG Injection 1
Celon Labs
Pack of 1 Units
₹273.06
MRP ₹333.00
18.00% OFF
Platin 10 MG Injection 20 ML
Platin 10 MG Injection 20 ML
Cadila Pharmaceuticals Ltd
Pack of 20 ML
₹64.14
MRP ₹78.22
18.00% OFF
Ciswel 50 MG Injection 50 ML
Ciswel 50 MG Injection 50 ML
Getwell Oncology Pvt Ltd
Pack of 50 ML
₹309.14
MRP ₹377.00
18.00% OFF

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