Cisatracurium is primarily used to relax skeletal muscles during surgery and to facilitate mechanical ventilation in intensive care settings. It belongs to the group of medicines known as skeletal muscle relaxants.
Secondary uses include facilitating tracheal intubation and aiding mechanical ventilation in intensive care units (ICUs).
Bradycardia or slow heart rate
Hypotension or low blood pressure
Facial flushing
Bronchospasm or tightening of airways
Cisatracurium is a non-depolarising neuromuscular blocker (skeletal muscle relaxant).
It works by competitively binding to nicotinic acetylcholine receptors at the neuromuscular junction, blocking the action of acetylcholine. This prevents the muscle cell membrane from depolarizing, leading to muscle paralysis and enabling controlled muscle relaxation during surgical procedures.
BDS, MDS
BMS, FMC, MD Resident
Cisatracurium is available as an injectable solution.
It is administered through the intravenous route.
This medicine is meant for use in adults and adolescents in surgical settings or intensive care units.
Cisatracurium is contraindicated in patients with known hypersensitivity to it or other neuromuscular blockers.
It is also contraindicated in patients with a personal or family history of malignant hyperthermia.
This medicine can interact with inhalational anaesthetics (e.g., Isoflurane), antibiotics (e.g., Gentamicin), local anaesthetics (e.g., Lidocaine), magnesium salts (e.g., Magnesium sulfate), antiarrhythmics (e.g., Procainamide, Quinidine), and anticonvulsants (e.g., Phenytoin, Carbamazepine). These interactions may potentiate or prolong the neuromuscular blockade effect, requiring careful monitoring.
Chances for overdose are less as it is administered to you by a healthcare professional. However, an overdose of Cisatracurium may lead to excessive muscle paralysis, respiratory depression, and hemodynamic instability. Immediate medical intervention is required to support breathing and circulatory functions.
If a scheduled dose of Cisatracurium is missed during continuous infusion in a clinical setting, it should be administered as soon as possible under the oversight of medical staff. Ensure that dosing schedules are strictly monitored to avoid missing doses.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If experiencing mild flushing or slight hypotension, ensure adequate hydration by drinking water.
Adjust the timing of subsequent doses under your doctor’s advice if initial side effects occur.
Cisatracurium is used under controlled medical settings such as surgeries or ICU environments; it does not directly apply to driving or operating machinery contexts.
The safety of Cisatracurium for use during pregnancy and lactation has not been established. It should only be used if clearly needed and prescribed by a doctor.
Caution is advised when using Cisatracurium in patients with neuromuscular disorders like myasthenia gravis, as well as those with underlying cardiac conditions.
Patients with respiratory diseases such as asthma should be closely monitored due to the risk of bronchospasm.
Patients undergoing treatment requiring Cisatracurium should follow specific preoperative fasting guidelines as advised by their doctor.
Post-treatment, it may be recommended to consume easily digestible foods and increase fluid intake to aid recovery.
Avoid activities requiring complete muscular function until the effects of Cisatracurium have fully worn off, as guided by healthcare professionals.
Maintain regular follow-ups with your doctor to monitor recovery from anaesthesia or sedation involving the use of Cisatracurium.
Frequently asked questions
No, Cisatracurium is not a steroid. It is a non-depolarizing neuromuscular blocker used to induce muscle relaxation during surgery. It works by blocking the action of acetylcholine at the neuromuscular junction, which prevents muscle contraction.
Cisatracurium has no significant direct effect on mood or emotions. However, it is important to note that individual responses to medications can vary.
There is no reported effect of Cisatracurium on appetite. However, if you notice any significant changes in your eating habits while on this medication, it is advisable to consult your doctor.
Cisatracurium does not have any known addictive potential. It is a neuromuscular blocking agent and its effects are reversible once the medicine is discontinued.
Prescription regulations may vary depending on the country and state you live in. Some places may have services that allow online consultations with a doctor who can provide a prescription, given they deem it necessary. Always consult a doctor for appropriate medical advice.
Cisatracurium starts working within 2-4 minutes after being administered as a bolus injection, with maximum paralysis occurring in 4-10 minutes.
If you have had allergic reactions to certain medications in the past, you should inform your doctor before starting any new treatment, including Cisatracurium. Although it is rare, some patients may have an allergic reaction to this medication.
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