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Ciprofloxacin + Metronidazole

Uses of Ciprofloxacin + Metronidazole

  • The primary use of Ciprofloxacin + Metronidazole is for managing infections caused by bacteria. This medicine belongs to the group of antibiotics specifically, the fluoroquinolone class (Ciprofloxacin) and nitroimidazole group (Metronidazole).

  • Secondary uses include the management of a variety of infections like intra-abdominal infections (e.g., peritonitis, appendicitis, diverticulitis), pelvic inflammatory disease, endocarditis, bone and joint infections, pneumonia and lung abscesses, skin and soft tissue infections, and for surgical prophylaxis.

Side effects of Ciprofloxacin + Metronidazole

  • Nausea

  • Diarrhoea

  • Vomiting

  • Abdominal discomfort or pain

  • Headache

How Ciprofloxacin + Metronidazole works

  • Ciprofloxacin + Metronidazole is a combination of two antibiotics.

  • Ciprofloxacin belongs to a class of medicines called fluoroquinolones. It works by stopping the action of two enzymes, DNA gyrase and topoisomerase IV, needed by bacteria to copy and repair their DNA. This stops the bacteria from growing and multiplying.

  • Metronidazole is a nitroimidazole antibiotic. It enters bacteria and gets converted into unstable molecules by certain enzymes inside these bacteria. These unstable molecules damage the bacterial DNA, which eventually kills the bacteria.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ciprofloxacin + Metronidazole can be taken orally (tablets and oral suspensions, and intravenously (injection).

Age and Dose Restrictions

  • This medicine is meant for adults and children, though specific age recommendations may vary depending on the condition being managed.

Contraindications

  • This medicine is contraindicated in patients with a history of seizures and in individuals with myasthenia gravis due to the risk of worsening muscle weakness. It should also not be used by patients with known hypersensitivity to either ciprofloxacin or metronidazole.

Other Medications to Avoid

  • This combination may interact with muscle relaxants (such as tizanidine), respiratory medications (like theophylline), blood thinners (such as warfarin), and diabetes medications (like glyburide).

Overdose and Missed Dose

  • An overdose of Ciprofloxacin + Metronidazole may lead to severe nausea, vomiting, dizziness, or more serious neurological symptoms. If these occur, contacting a doctor immediately is crucial.

  • If you miss a dose, take it as soon as you remember unless it is nearly time for your next dose. Do not double up on doses to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Adjusting the timing of taking the medication might help manage gastrointestinal upset such as nausea or a metallic taste in the mouth.

  • Drinking plenty of water can help alleviate some side effects like dry mouth or dehydration.

Use in Driving and Operating Machinery

  • Ciprofloxacin + Metronidazole may cause dizziness or confusion in some individuals. It is advised to avoid driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

  • The use of Ciprofloxacin + Metronidazole during pregnancy and lactation should only be considered if absolutely necessary and prescribed by a doctor. Consulting a doctor before using this medicine in these conditions is crucial.

Caution in Other Conditions

  • Caution is advised for patients with liver or kidney conditions when taking Ciprofloxacin + Metronidazole due to potential alterations in medicine metabolism and excretion.

  • Individuals with a history of tendon disorders should also exercise caution due to the potential medicine-associated risk of tendon rupture.

Special Dietary and Lifestyle Recommendations

  • Ensure adequate hydration while taking this medication to help reduce the risk of crystal formation in urine and support overall kidney function.

  • Maintaining good personal hygiene can help prevent reinfection or spreading infections when managing skin and soft tissue infections.

  • A balanced diet rich in nutrients can support immune function, which is crucial when fighting infections.

Frequently asked questions

No, Ciprofloxacin + Metronidazole is not a steroid. It is a combination of antibiotics used to manage various types of bacterial infections.

Ciprofloxacin + Metronidazole may potentially affect sleep patterns, though it's not a common side effect. Ciprofloxacin can cause insomnia or restlessness in some cases, and Metronidazole can lead to dizziness or confusion. If you experience significant sleep disturbances, consult your doctor.

There is no evidence to suggest that Ciprofloxacin + Metronidazole has direct effects on fertility. Yet, if you have concerns about fertility or are trying to conceive, it is best to discuss this with your doctor.

No specific diet restrictions are necessary while taking this medicine unless advised by your doctor. However, proper nutrition can support overall health and recovery from illness.

Yes, it is usually safe if taken as per the prescribed dose and duration recommended by your doctor.

The duration for the medicine to show its effects may vary depending on the type and severity of the infection. Consult your doctor for precise information.

Ciprofloxacin + Metronidazole generally requires a doctor's prescription and is not typically available over the counter.

Terms & Conditions


Available medicines for CIPROFLOXACIN + METRONIDAZOLE
Ciprogyl 100/125 MG Syrup 30 ML
Ciprogyl 100/125 MG Syrup 30 ML
Mankind Pharmaceuticals Ltd.
Pack of 30 ML
₹33.05
MRP ₹40.30
18.00% OFF
Tropenor 125/100 MG Suspension 60 ML
Tropenor 125/100 MG Suspension 60 ML
Moraceae Pharmaceuticals Pvt Ltd
Pack of 60 ML
₹33.10
MRP ₹40.37
18.00% OFF
Tropenor 125/100 MG Suspension 30 ML
Tropenor 125/100 MG Suspension 30 ML
Moraceae Pharmaceuticals Pvt Ltd
Pack of 30 ML
₹26.24
MRP ₹32.00
18.00% OFF
Ciprogyl 100/125 MG Suspension 60 ML
Ciprogyl 100/125 MG Suspension 60 ML
Mankind Pharmaceuticals Ltd.
Pack of 60 ML
₹23.78
MRP ₹29.00
18.00% OFF

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