Chlorthalidone + Losartan
Uses of Chlorthalidone + Losartan
The primary use of Chlorthalidone + Losartan is to manage high blood pressure (hypertension). This combination medication belongs to the classes of medicines known as thiazide-like diuretics and angiotensin II receptor blockers (ARBs).
In addition, Chlorthalidone + Losartan may also be used to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy (enlargement of the heart). It also aids in protecting the kidneys from damage in patients with type 2 diabetes and hypertension.
Side effects of Chlorthalidone + Losartan
Dizziness
Upper respiratory tract infections
Cough
Fatigue
Electrolyte disturbances (hypokalemia, hyponatremia)
How Chlorthalidone + Losartan works
Chlorthalidone + Losartan is a combination of a diuretic and an angiotensin II receptor blocker, used to manage high blood pressure.
Chlorthalidone is a thiazide-like diuretic. It works on the kidneys to increase the removal of excess salt and water from your body. This reduces the blood volume that needs to be pumped, lowering blood pressure.
Losartan is an angiotensin II receptor blocker (ARB). This reduces the blood volume that needs to be pumped, lowering blood pressure. By blocking this action, Losartan allows blood vessels to relax and widen, reducing their pressure.
As a result of these combined actions, Chlorthalidone + Losartan effectively manages high blood pressure.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage forms available
Chlorthalidone + Losartan is available for use in the form of oral tablets.
Age and dose restrictions
This medicine is intended for use by adults above 18 years of age.
Contraindications
Chlorthalidone + Losartan is contraindicated in patients with known allergies to either component of this combination.
It is also contraindicated in patients with anuria, a condition where the kidneys do not produce urine.
Other medications to avoid
This combination may interact with diuretics (such as furosemide and hydrochlorothiazide), NSAIDs (like ibuprofen, naproxen) and Potassium supplements/potassium-sparing diuretics (like spironolactone).
Overdose and missed dose
An overdose of Chlorthalidone + Losartan may cause dizziness and fainting, and could potentially harm the kidneys. If you observe these symptoms, inform your doctor immediately.
If you forget to take this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.
Management of side effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage side effects like dizziness or lightheadedness.
Try taking this medication with food if it causes stomach upset.
Use in driving and operating machinery
Chlorthalidone + Losartan may cause dizziness and lightheadedness. If this happens, avoid driving or operating heavy machinery.
Use in pregnancy and lactation
This medicine is not recommended during pregnancy and breastfeeding unless deemed necessary by your doctor.
Caution in other conditions
Patients with severe kidney disease or severe liver disease need to be cautious while taking Chlorthalidone + Losartan.
Special dietary and lifestyle recommendations
Limiting salt intake can help manage high blood pressure.
Regularly monitoring your blood pressure can help keep track of the effectiveness of the medicine.
Regular physical exercise can help in managing high blood pressure effectively.
Frequently asked questions
Can Chlorthalidone + Losartan be used for weight loss?
No, Chlorthalidone + Losartan is not indicated for weight loss. This combination is used for managing high blood pressure (hypertension). It is not advisable to use medications for purposes other than their intended use. Always consult your doctor before starting any new medication.
Can Chlorthalidone + Losartan cause mood changes?
Chlorthalidone + Losartan is not directly associated with affecting mood change. If you experience unexplained changes in mood while taking this medication, it is important to discuss it with your doctor.
Can taking Chlorthalidone + Losartan cause hair loss?
Hair loss is not a common side effect of Chlorthalidone + Losartan. However, if you notice sudden or excessive hair loss, you should consult your doctor.
Is it safe to take Chlorthalidone + Losartan for a long time?
Chlorthalidone + Losartan is usually prescribed for long-term management of hypertension. The duration of the treatment should be determined by your doctor based on your condition and response to the treatment.
Are there any natural alternatives to Chlorthalidone + Losartan?
While certain lifestyle modifications like a low-sodium diet, exercise, and stress management can help manage blood pressure, but they cannot replace the need for medication in patients with hypertension. Always consult your doctor before making any changes to your medication regimen.
Can Chlorthalidone + Losartan cause dependency?
Chlorthalidone + Losartan does not cause physical or psychological dependency as it does not have any narcotic or addictive substances. However, stopping the medication abruptly without consulting your doctor can lead to uncontrolled blood pressure.
How long does Chlorthalidone + Losartan stay in my system?
This can vary depending on many factors, including your metabolism and kidney function. In general, the active ingredients in Chlorthalidone + Losartan reach their peak concentration in your blood within 1 to 6 hours after you take this medicine.
Chlorthalidone + Losartan in other salts
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